Carcinogenicity assessment of industrial chemicals 1,2-dichlorobenzene, 2-methoxyethanol and anisol via Bhas 42 cell transformation assay

Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells

(2022) Kiyomi Ohmori et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro

(2018) Maria Grazia Mascolo et al.   CARCINOGENESIS

Marked for death: targeting epigenetic changes in cancer

(2017) Sophia Xiao Pfister et al.   NATURE REVIEWS DRUG DISCOVERY

Transformation Assay in Bhas 42 Cells: A Model Using Initiated Cells to Study Mechanisms of Carcinogenesis and Predict Carcinogenic Potential of Chemicals

(2015) Kiyoshi Sasaki et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

In vitro and in vivo testing methods of epigenomic endpoints for evaluating endocrine disruptors

(2014) John Greally   ALTEX-Alternatives to Animal Experimentation

Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation

(2013) Z. Herceg et al.   CARCINOGENESIS

Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?

(2012) Romualdo Benigni   Expert Opinion on Drug Metabolism & Toxicology

Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for Predictive Toxicology

(2011) Romualdo Benigni et al.   CHEMICAL REVIEWS

The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies

(2011) R. Benigni et al.   MUTAGENESIS

An international validation study of a Bhas 42 cell transformation assay for the prediction of chemical carcinogenicity

(2011) Ayako Sakai et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Alternatives to the carcinogenicity bioassay:in silicomethods, and thein vitroandin vivomutagenicity assays

(2010) Romualdo Benigni et al.   Expert Opinion on Drug Metabolism & Toxicology

Research on Early-Stage Carcinogenesis: Are We Approaching Paradigm Instability?

(2010) Stuart G. Baker et al.   JOURNAL OF CLINICAL ONCOLOGY

A Bhas 42 cell transformation assay on 98 chemicals: The characteristics and performance for the prediction of chemical carcinogenicity

(2010) Ayako Sakai et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods

(2010) Michael D. Waters et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Current and Future Application of Genetic Toxicity Assays: The Role and Value of In Vitro Mammalian Assays

(2009) Rosalie K. Elespuru et al.   TOXICOLOGICAL SCIENCES

A Preliminary Operational Classification System for Nonmutagenic Modes of Action for Carcinogenesis

(2008) D. Hattis et al.   CRITICAL REVIEWS IN TOXICOLOGY

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

More Toxin Tests Needed

(2008) J. Huff   SCIENCE