Integrative proteomic analysis reveals the cytoskeleton regulation and mitophagy difference between ischemic cardiomyopathy and dilated cardiomyopathy

Critical Role of the cGAS-STING Pathway in Doxorubicin-Induced Cardiotoxicity

(2023) Wei Luo et al.   CIRCULATION RESEARCH

The microtubule cytoskeleton in cardiac mechanics and heart failure

(2022) Matthew A. Caporizzo et al.   Nature Reviews Cardiology

Modulating Lysine Crotonylation in Cardiomyocytes Improves Myocardial Outcomes

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Proteomic characterization of post-translational modifications in drug discovery

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BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection

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Cardiac cAMP-PKA Signaling Compartmentalization in Myocardial Infarction

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A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies

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MARK4 controls ischaemic heart failure through microtubule detyrosination

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Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury

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Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy

(2021) Sara Ranjbarvaziri et al.   CIRCULATION

Myofilament Phosphorylation in Stem Cell Treated Diastolic Heart Failure

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Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis

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Integrative Proteomic Characterization of Human Lung Adenocarcinoma

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Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy

(2020) Mengbo Li et al.   Nature Communications

Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources

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On the role of tubulin, plectin, desmin and vimentin in the regulation of mitochondrial energy fluxes in muscle cells

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Autophagy-Independent Functions of the Autophagy Machinery

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Myocardial substrate changes in advanced ischaemic and advanced dilated human heart failure

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Role of Targeted Therapy in Dilated Cardiomyopathy: The Challenging Road Toward a Personalized Approach

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Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets

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Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

(2019) Hongryeol Park et al.   Nature Communications

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

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Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure

(2018) Christina Yingxian Chen et al.   NATURE MEDICINE

Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography–mass spectrometry

(2018) Philipp Mertins et al.   Nature Protocols

Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice

(2018) Dajun Zhao et al.   Oxidative Medicine and Cellular Longevity

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(2018) Kristian Thygesen et al.   EUROPEAN HEART JOURNAL

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Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

(2018) Mary E. Sweet et al.   BMC GENOMICS

Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process

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Reverse remodelling and myocardial recovery in heart failure

(2017) Gene H. Kim et al.   Nature Reviews Cardiology

Mechanical Properties of the Cytoskeleton and Cells

(2017) Adrian F. Pegoraro et al.   Cold Spring Harbor Perspectives in Biology

Region and cell-type resolved quantitative proteomic map of the human heart

(2017) Sophia Doll et al.   Nature Communications

A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse HeartNovelty and Significance

(2016) Matthew Ackers-Johnson et al.   CIRCULATION RESEARCH

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(2016) Piotr Ponikowski et al.   EUROPEAN HEART JOURNAL

The Diagnosis and Evaluation of Dilated Cardiomyopathy

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Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes

(2016) P. Robison et al.   SCIENCE

The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

(2015) Cecilia Lindskog et al.   BMC GENOMICS

Titration of mitochondrial fusion rescuesMff-deficient cardiomyopathy

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Measuring In Vivo Mitophagy

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Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

Super-Suppression of Mitochondrial Reactive Oxygen Species Signaling Impairs Compensatory Autophagy in Primary Mitophagic Cardiomyopathy

(2014) Moshi Song et al.   CIRCULATION RESEARCH

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

(2014) S. Ounzain et al.   EUROPEAN HEART JOURNAL

Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction

(2014) Ying Peng et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial Contagion Induced by Parkin Deficiency in Drosophila Hearts and Its Containment by Suppressing Mitofusin

(2013) Poonam Bhandari et al.   CIRCULATION RESEARCH

Systematic research on the pretreatment of peptides for quantitative proteomics using a C18microcolumn

(2013) Linhui Zhai et al.   PROTEOMICS

Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells

(2012) Cuihong Zhou et al.   Autophagy

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC

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A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Phospho.ELM: a database of phosphorylation sites--update 2011

(2010) H. Dinkel et al.   NUCLEIC ACIDS RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

PhosphoPOINT: a comprehensive human kinase interactome and phospho-protein database

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