Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy

(2019) Andreas Brodehl et al.   Translational Research

Integrin-Linked Kinase Regulates Bone Formation by Controlling Cytoskeletal Organization and Modulating BMP and Wnt Signaling in Osteoprogenitors

(2017) Marian Dejaeger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Integrin-linked kinase affects signaling pathways and migration in thyroid cancer cells and is a potential therapeutic target

(2016) Lawrence A. Shirley et al.   SURGERY

Identification of novel KIF11 mutations in patients with familial exudative vitreoretinopathy and a phenotypic analysis

(2016) Jia-Kai Li et al.   Scientific Reports

KIF11mutations are a common cause of autosomal dominant familial exudative vitreoretinopathy

(2015) Huan Hu et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Endothelial Alpha-Parvin Controls Integrity of Developing Vasculature and Is Required for Maintenance of Cell-Cell Junctions

(2015) A. Fraccaroli et al.   CIRCULATION RESEARCH

Integrin-linked kinase regulates the niche of quiescent epidermal stem cells

(2015) Jessica Morgner et al.   Nature Communications

Integrin β1 controls VE-cadherin localization and blood vessel stability

(2015) Hiroyuki Yamamoto et al.   Nature Communications

Familial exudative vitreoretinopathy and related retinopathies

(2014) D F Gilmour   EYE

Deletion of integrin linked kinase in endothelial cells results in defective RTK signaling caused by caveolin 1 mislocalization

(2013) D. Malan et al.   DEVELOPMENT

Notch controls retinal blood vessel maturation and quiescence

(2013) M. Ehling et al.   DEVELOPMENT

ILK modulates epithelial polarity and matrix formation in hair follicles

(2013) Alena Rudkouskaya et al.   MOLECULAR BIOLOGY OF THE CELL

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

ZNF408 is mutated in familial exudative vitreoretinopathy and is crucial for the development of zebrafish retinal vasculature

(2013) R. W. J. Collin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin signaling in vascular function

(2012) Nikolay L. Malinin et al.   CURRENT OPINION IN HEMATOLOGY

The Diaphragms of Fenestrated Endothelia: Gatekeepers of Vascular Permeability and Blood Composition

(2012) Radu V. Stan et al.   DEVELOPMENTAL CELL

Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice

(2012) Leonie Herrnberger et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The deletion of Math5 disrupts retinal blood vessel and glial development in mice

(2011) Malia M. Edwards et al.   EXPERIMENTAL EYE RESEARCH

Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice

(2011) Gwénola Boulday et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Focal adhesion kinase and tumour angiogenesis

(2011) Tanguy Lechertier et al.   JOURNAL OF PATHOLOGY

Role of the Cytoskeleton in Formation and Maintenance of Angiogenic Sprouts

(2011) Kayla J. Bayless et al.   JOURNAL OF VASCULAR RESEARCH

Mutations in TSPAN12 Cause Autosomal-Dominant Familial Exudative Vitreoretinopathy

(2010) James A. Poulter et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The oncogenic and growth-suppressive functions of the integrin-linked kinase are distinguished by JNK1 expression in human cancer cells

(2010) Adam David Durbin et al.   CELL CYCLE

Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP

(2010) Konstantinos Nikopoulos et al.   HUMAN MUTATION

Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice

(2010) Mara E Pitulescu et al.   Nature Protocols

The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease

(2010) Xin Ye et al.   TRENDS IN MOLECULAR MEDICINE

Integrin linked kinase (ILK) expression and function in vascular smooth muscle cells

(2010) Bernard Ho et al.   Cell Adhesion & Migration

Mechanisms of Vessel Branching

(2009) Frederik De Smet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization

(2009) Xin Ye et al.   CELL

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions

(2009) Koichi Fukuda et al.   MOLECULAR CELL

Integrin-linked kinase is an adaptor with essential functions during mouse development

(2009) Anika Lange et al.   NATURE

Plasmalemmal Vesicle Associated Protein-1 (PV-1) is a marker of blood-brain barrier disruption in rodent models

(2008) Eveline H Shue et al.   BMC NEUROSCIENCE

Cell-autonomous requirement for  1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

(2008) T. R. Carlson et al.   DEVELOPMENT

Efficient, inducible Cre-recombinase activation in vascular endothelium

(2008) Suzanne Claxton et al.   GENESIS

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY

The structural basis of integrin-linked kinase-PINCH interactions

(2008) B. P. Chiswell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA