Efflux pump Rv1258c activates novel functions of the oxidative stress and via the VII secretion system ESX-3-mediated iron metabolic pathway in Mycobacterium tuberculosis

H2O2 concentration-dependent kinetics of gene expression: linking the intensity of oxidative stress and mycobacterial physiological adaptation

(2022) Mengying Wu et al.   Emerging Microbes & Infections

Rv1258c acts as a drug efflux pump and growth controlling factor in Mycobacterium tuberculosis

(2022) Hongbing Jia et al.   TUBERCULOSIS

The TbD1 Locus Mediates a Hypoxia-Induced Copper Response in Mycobacterium bovis

(2022) Ruoyao Ma et al.   Frontiers in Microbiology

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Highly accurate protein structure prediction for the human proteome

(2021) Kathryn Tunyasuvunakool et al.   NATURE

Efflux pumps in Mycobacterium tuberculosis and their inhibition to tackle antimicrobial resistance

(2021) Mark Laws et al.   TRENDS IN MICROBIOLOGY

PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis

(2020) Qinglan Wang et al.   SCIENCE

TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages

(2020) Daria Bottai et al.   Nature Communications

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis

(2020) Lei Zhang et al.   PLoS Pathogens

The ABC exporter IrtAB imports and reduces mycobacterial siderophores

(2020) Fabian M. Arnold et al.   NATURE

Evidence for expanding the role of streptomycin in the management of drug-resistant M. tuberculosis

(2020) Keira A. Cohen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

How Microbes Evolved to Tolerate Oxygen

(2020) Maryam Khademian et al.   TRENDS IN MICROBIOLOGY

Mutations in Efflux Pump Rv1258c (Tap) Cause Resistance to Pyrazinamide, Isoniazid, and Streptomycin in M. tuberculosis

(2019) Jiayun Liu et al.   Frontiers in Microbiology

Architecture of the mycobacterial type VII secretion system

(2019) Nikolaos Famelis et al.   NATURE

Membrane activity profiling of small molecule B. subtilis growth inhibitors utilizing novel duel-dye fluorescence assay

(2018) S. McAuley et al.   MedChemComm

The MmpS6-MmpL6 operon is an oxidative stress response system providing selective advantage to Mycobacterium tuberculosis in stress

(2018) Prabhakar Arumugam et al.   JOURNAL OF INFECTIOUS DISEASES

Mycobacterium tuberculosis Major Facilitator Superfamily Transporters

(2017) Ping Li et al.   JOURNAL OF MEMBRANE BIOLOGY

Improving basic and membrane protein MS detection of the culture filtrate proteins from Mycobacterium tuberculosis H37Rv by biomimetic affinity prefractionation

(2017) Guorong Ma et al.   PROTEOMICS

Transcriptional Profiling of Mycobacterium tuberculosis Exposed toIn VitroLysosomal Stress

(2016) Wenwei Lin et al.   INFECTION AND IMMUNITY

Separable roles forMycobacterium tuberculosisESX-3 effectors in iron acquisition and virulence

(2016) JoAnn M. Tufariello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein–protein binding affinity prediction from amino acid sequence

(2014) K. Yugandhar et al.   BIOINFORMATICS

Roles of the two type II NADH dehydrogenases in the survival of Mycobacterium tuberculosis in vitro

(2014) Disha Awasthy et al.   GENE

HemI: A Toolkit for Illustrating Heatmaps

(2014) Wankun Deng et al.   PLoS One

Streptomycin Resistance and Lineage-Specific Polymorphisms in Mycobacterium tuberculosisgidBGene

(2011) Fernanda S. Spies et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

Role of the Mycobacterium tuberculosis P55 Efflux Pump in Intrinsic Drug Resistance, Oxidative Stress Responses, and Growth

(2009) S. Ramon-Garcia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a Mycobacterium tuberculosis ESX-3 Conditional Mutant: Essentiality and Rescue by Iron and Zinc

(2009) A. Serafini et al.   JOURNAL OF BACTERIOLOGY

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

(2009) M. S. Siegrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relative Quantification of Proteins in Human Cerebrospinal Fluids by MS/MS Using 6-Plex Isobaric Tags

(2008) Loïc Dayon et al.   ANALYTICAL CHEMISTRY