Mycobacterium tuberculosis Major Facilitator Superfamily Transporters

Global regulator SoxR is a negative regulator of efflux pump gene expression and affects antibiotic resistance and fitness in Acinetobacter baumannii

(2017) Henan Li et al.   MEDICINE

Antibiotic resistance mechanisms in M. tuberculosis: an update

(2016) Liem Nguyen   ARCHIVES OF TOXICOLOGY

H. pylori’s BabA Embraces Change

(2016) Emily Goers Sweeney et al.   Cell Host & Microbe

Molecular analysis of genetic mutations among cross-resistant second-line injectable drugs reveals a new resistant mutation in Mycobacterium tuberculosis

(2016) Lesibana Malinga et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Development of efflux pump inhibitors in antituberculosis therapy

(2016) Lele Song et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Sialic acid transporter NanT participates in Tannerella forsythia biofilm formation and survival on epithelial cells

(2016) Kiyonobu Honma et al.   MICROBIAL PATHOGENESIS

Multidrug resistance operon emrAB contributes for chromate and ampicillin co-resistance in a Staphylococcus strain isolated from refinery polluted river bank

(2016) He Zhang et al.   SpringerPlus

Structural Biology of the Major Facilitator Superfamily Transporters

(2015) Nieng Yan   Annual Review of Biophysics

Implications of Mycobacterium Major Facilitator Superfamily for Novel Measures against Tuberculosis

(2015) Rui Wang et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Study of efflux pump gene expression in rifampicin-monoresistant Mycobacterium tuberculosis clinical isolates

(2015) Guilian Li et al.   JOURNAL OF ANTIBIOTICS

Investigation of Mutations in Transcription Factors of Efflux Pump Genes in Fluconazole-Resistant Candida albicans Strains Overexpressing the Efflux Pumps

(2015) Kemal Turan KALKANDELEN et al.   MIKROBIYOLOJI BULTENI

The DNA-binding network of Mycobacterium tuberculosis

(2015) Kyle J. Minch et al.   Nature Communications

Efflux Pump Gene Expression in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates

(2015) Guilian Li et al.   PLoS One

Novel role of a family of major facilitator transporters in biofilm development and virulence ofCandida albicans

(2014) Abdul Haseeb Shah et al.   BIOCHEMICAL JOURNAL

Genome-wide Mycobacterium tuberculosis variation (GMTV) database: a new tool for integrating sequence variations and epidemiology

(2014) Ekaterina N Chernyaeva et al.   BMC GENOMICS

Comparative analyses of proteins from Haemophilus influenzae biofilm and planktonic populations using metabolic labeling and mass spectrometry

(2014) Deborah MB Post et al.   BMC MICROBIOLOGY

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Crystal structure of the human glucose transporter GLUT1

(2014) Dong Deng et al.   NATURE

Crystal structure of the plant dual-affinity nitrate transporter NRT1.1

(2014) Ji Sun et al.   NATURE

Structure-based mechanism for Na+/melibiose symport by MelB

(2014) Abdul S. Ethayathulla et al.   Nature Communications

Mycobacterium Tuberculosis Proteome Microarray for Global Studies of Protein Function and Immunogenicity

(2014) Jiaoyu Deng et al.   Cell Reports

Crystal structure of a eukaryotic phosphate transporter

(2013) Bjørn P. Pedersen et al.   NATURE

Crystal structure of a nitrate/nitrite exchanger

(2013) Hongjin Zheng et al.   NATURE

Crystal structure of a glucose/H+ symporter and its mechanism of action

(2013) C. V. Iancu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

(2013) J. J. Gartner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT

(2013) S. Doki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A

(2013) Daohua Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural advances for the major facilitator superfamily (MFS) transporters

(2013) Nieng Yan   TRENDS IN BIOCHEMICAL SCIENCES

Role of efflux pumps in the antibiotic resistance of bacteria embedded in a biofilm

(2013) Sara M. Soto   Virulence

Structure and Mechanism of a Nitrate Transporter

(2013) Hanchi Yan et al.   Cell Reports

Study of the Rifampin Monoresistance Mechanism in Mycobacterium tuberculosis

(2012) Y. Pang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional and Genetic Characterization of the Tap Efflux Pump in Mycobacterium bovis BCG

(2012) Santiago Ramón-García et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efflux Pumps of Mycobacterium tuberculosis Play a Significant Role in Antituberculosis Activity of Potential Drug Candidates

(2012) Meenakshi Balganesh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Alternating access mechanism in the POT family of oligopeptide transporters

(2012) Nicolae Solcan et al.   EMBO JOURNAL

Loss of or inhibition of all multidrug resistance efflux pumps of Salmonella enterica serovar Typhimurium results in impaired ability to form a biofilm

(2012) S. Baugh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Crystal structure of a bacterial homologue of glucose transporters GLUT1–4

(2012) Linfeng Sun et al.   NATURE

Basic Residues R260 and K357 Affect the Conformational Dynamics of the Major Facilitator Superfamily Multidrug Transporter LmrP

(2012) Wei Wang et al.   PLoS One

Amino Acid Transporter Genes Are Essential for FLO11-Dependent and FLO11-Independent Biofilm Formation and Invasive Growth in Saccharomyces cerevisiae

(2012) Rasmus Torbensen et al.   PLoS One

Mutational Analysis of the Respiratory Nitrate Transporter NarK2 of Mycobacterium tuberculosis

(2012) Michelle M. Giffin et al.   PLoS One

Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin-resistantMycobacterium tuberculosisthrough Efflux

(2011) Gail E. Louw et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Roles of Multidrug Efflux Pumps on the Biofilm Formation of Escherichia coli K-12

(2011) KAYO MATSUMURA et al.   BIOCONTROL SCIENCE

Synthesis and evaluation of inhibitors of bacterial drug efflux pumps of the major facilitator superfamily

(2011) Babajide O. Okandeji et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Alternating-Access Mechanism of MFS Transporters Arises from Inverted-Topology Repeats

(2011) Sebastian Radestock et al.   JOURNAL OF MOLECULAR BIOLOGY

Roles of DHA2 Family Transporters in Drug Resistance and Iron Homeostasis in Acinetobacter spp.

(2011) Karl A. Hassan et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2

(2010) Simon Newstead et al.   EMBO JOURNAL

Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis

(2010) S. Sharma et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Regulation and Function of Escherichia coli Sugar Efflux Transporter A (SetA) during Glucose-Phosphate Stress

(2010) Y. Sun et al.   JOURNAL OF BACTERIOLOGY

Structure of a fucose transporter in an outward-open conformation

(2010) Shangyu Dang et al.   NATURE

Evolution of the 12-Spanner Drug:H+ Antiporter DHA1 Family in Hemiascomycetous Yeasts

(2010) Paulo Jorge Dias et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Role of the Mycobacterium tuberculosis P55 Efflux Pump in Intrinsic Drug Resistance, Oxidative Stress Responses, and Growth

(2009) S. Ramon-Garcia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cells need safety valves

(2009) Antoine Danchin   BIOESSAYS

Identification of a novel ABC transporter required for desiccation tolerance, and biofilm formation inRhizobium leguminosarumbv.viciae3841

(2009) Elizabeth M. Vanderlinde et al.   FEMS MICROBIOLOGY ECOLOGY

Characterization of a novel sialic acid transporter of the sodium solute symporter (SSS) family and in vivo comparison with known bacterial sialic acid transporters

(2009) Emmanuele Severi et al.   FEMS MICROBIOLOGY LETTERS

Microarray Analysis of Efflux Pump Genes in Multidrug-Resistant Mycobacterium tuberculosis During Stress Induced by Common Anti-Tuberculous Drugs

(2009) Anuj Kumar Gupta et al.   Microbial Drug Resistance

The high-affinity phosphate transporter Pst in Proteus mirabilis HI4320 and its importance in biofilm formation

(2009) G. A. O'May et al.   MICROBIOLOGY-SGM

Ins and Outs of Major Facilitator Superfamily Antiporters

(2008) Christopher J. Law et al.   Annual Review of Microbiology

A Putative ABC Transporter Is Involved in Negative Regulation of Biofilm Formation by Listeria monocytogenes

(2008) X. Zhu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Inactivation of Efflux Pumps Abolishes Bacterial Biofilm Formation

(2008) M. Kvist et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mechanisms of drug efflux and strategies to combat them: Challenging the efflux pump of Gram-negative bacteria

(2008) Jean-Marie Pagès et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Characteristics of biofilm formation by Candida tropicalis and antifungal resistance

(2008) Fernando César Bizerra et al.   FEMS YEAST RESEARCH

Differentially expressed genes in Mycobacterium tuberculosis H37Rv under mild acidic and hypoxic conditions

(2008) S.-Y. Kim et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A Genomic View on Nitrogen Metabolism and Nitrogen Control in Mycobacteria

(2008) Johannes Amon et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5–MmpL5 efflux system

(2008) Anna Milano et al.   TUBERCULOSIS