Mitochondria-SR interaction and mitochondrial fusion/fission in the regulation of skeletal muscle metabolism

Endoplasmic reticulum-mitochondria miscommunication is an early and causal trigger of hepatic insulin resistance and steatosis

(2022) Agathe Beaulant et al.   JOURNAL OF HEPATOLOGY

Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle

(2022) Xue Lu et al.   Cell Death & Disease

Insulin resistance, diabetic kidney disease, and all-cause mortality in individuals with type 2 diabetes: a prospective cohort study

(2021) Giuseppe Penno et al.   BMC Medicine

Low abundance of Mfn2 protein correlates with reduced mitochondria‐SR juxtaposition and mitochondrial cristae density in human men skeletal muscle: Examining organelle measurements from TEM images

(2021) Mauricio Castro‐Sepulveda et al.   FASEB JOURNAL

Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans

(2021) Christopher L. Axelrod et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Insulin resistance, cardiovascular stiffening and cardiovascular disease

(2021) Michael A. Hill et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling

(2021) Pamela A. Kakimoto et al.   Redox Biology

The fasting‐feeding metabolic transition regulates mitochondrial dynamics

(2021) Mauricio Castro‐Sepúlveda et al.   FASEB JOURNAL

Relative lipid oxidation associates directly with mitochondrial fusion phenotype and mitochondria-sarcoplasmic reticulum interactions in human skeletal muscle

(2020) Mauricio Castro-Sepulveda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses

(2020) Yongquan Hu et al.   Autophagy

Direct Relationship Between Metabolic Flexibility Measured During Glucose Clamp and Prolonged Fast in Men

(2020) Rodrigo Fernández‐Verdejo et al.   Obesity

Swimming Differentially Affects T2DM-Induced Skeletal Muscle ER Stress and Mitochondrial Dysfunction Related to MAM

(2020) Zhe Zhang et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy

(2020) Anne Filipe et al.   CELL DEATH AND DIFFERENTIATION

Pathophysiological role of metabolic flexibility on metabolic health

(2020) Jose E. Galgani et al.   Obesity Reviews

Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production

(2020) David A. Patten et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

(2020) Alexandre Houzelle et al.   DIABETOLOGIA

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

(2019) María Isabel Hernández-Alvarez et al.   CELL

TFAM Enhances Fat Oxidation and Attenuates High Fat Diet Induced Insulin Resistance in Skeletal Muscle

(2019) Jin-Ho Koh et al.   DIABETES

Endurance exercise decreases protein synthesis and ER-mitochondria contacts in mice skeletal muscle

(2019) Audrey Merle et al.   JOURNAL OF APPLIED PHYSIOLOGY

Impaired Metabolic Flexibility to High-fat Overfeeding Predicts Future Weight Gain in Healthy Adults

(2019) Brittany Begaye et al.   DIABETES

Exercise and mitochondrial health

(2019) Jonathan M. Memme et al.   JOURNAL OF PHYSIOLOGY-LONDON

Metabolic Flexibility to Lipid Availability During Exercise is Enhanced in Individuals with High Insulin Sensitivity

(2018) Rodrigo Fernández-Verdejo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans

(2018) Emily Tubbs et al.   DIABETES

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

(2018) Verónica Eisner et al.   NATURE CELL BIOLOGY

Mitofusin 2: from functions to disease

(2018) Riccardo Filadi et al.   Cell Death & Disease

Mitochondrial dynamics in skeletal muscle insulin resistance and type 2 diabetes

(2018) CiarÁn E. Fealy et al.   Translational Research

Mitochondria-Associated Membranes Response to Nutrient Availability and Role in Metabolic Diseases

(2017) Pierre Theurey et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway

(2017) Yuehong Wang et al.   Cell Death & Disease

Power Grid Protection of the Muscle Mitochondrial Reticulum

(2017) Brian Glancy et al.   Cell Reports

Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications

(2017) Susana Rovira-Llopis et al.   Redox Biology

Metabolic regulation of mitochondrial dynamics

(2016) Prashant Mishra et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial Dynamics and Metabolic Regulation

(2016) Timothy Wai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondria-associated endoplasmic reticulum membranes allow adaptation of mitochondrial metabolism to glucose availability in the liver

(2016) Pierre Theurey et al.   Journal of Molecular Cell Biology

Mitochondrial Dynamics Is a Distinguishing Feature of Skeletal Muscle Fiber Types and Regulates Organellar Compartmentalization

(2015) Prashant Mishra et al.   Cell Metabolism

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics

(2015) Angelika S. Rambold et al.   DEVELOPMENTAL CELL

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

(2015) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance

(2014) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation

(2014) Prashant Mishra et al.   Cell Metabolism

Exercise training decreases activation of the mitochondrial fission protein dynamin-related protein-1 in insulin-resistant human skeletal muscle

(2014) Ciaran E. Fealy et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

(2013) E.P. Taddeo et al.   Molecular Metabolism

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

(2012) D. Sebastian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Mitochondria fine-tune the slow Ca2+ transients induced by electrical stimulation of skeletal myotubes

(2010) Veronica Eisner et al.   CELL CALCIUM

SR/ER–mitochondrial local communication: Calcium and ROS

(2009) György Csordás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

ATP Released by Electrical Stimuli Elicits Calcium Transients and Gene Expression in Skeletal Muscle

(2009) Sonja Buvinic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptor δ regulates mitofusin 2 expression in the heart

(2009) Yuquan Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells

(2008) Rafael Herling Lambertucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis

(2008) T. Szado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA