Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling

CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4

(2019) Xiphias Ge Zhu et al.   MOLECULAR CELL

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

(2019) Manuele Piccolis et al.   MOLECULAR CELL

Distinct Metabolic Patterns During Microglial Remodeling by Oleate and Palmitate

(2019) Bruno Chausse et al.   BIOSCIENCE REPORTS

Metabolic implications of organelle–mitochondria communication

(2019) Isabel Gordaliza‐Alaguero et al.   EMBO REPORTS

Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis

(2019) Alicia J. Kowaltowski et al.   FASEB JOURNAL

Mitochondrial Dynamics and Its Involvement in Disease

(2019) David C. Chan   Annual Review of Pathology-Mechanisms of Disease

Protective effect of metformin against palmitate-induced hepatic cell death

(2019) Yana Geng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Biological Production, Detection, and Fate of Hydrogen Peroxide

(2018) Christine C. Winterbourn   ANTIOXIDANTS & REDOX SIGNALING

Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis

(2018) Ajit S. Divakaruni et al.   Cell Metabolism

Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion

(2018) Wei-Feng Cai et al.   CELL RESEARCH

Glutamate-oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux

(2018) Robert A. Egnatchik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet

(2018) Annelise Francisco et al.   JOURNAL OF NEUROCHEMISTRY

Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice

(2017) Claudia D.C. Navarro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Free fatty acids profile among lean, overweight and obese non-alcoholic fatty liver disease patients: a case – control study

(2017) Rennan Feng et al.   Lipids in Health and Disease

Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging

(2017) David Sebastián et al.   TRENDS IN MOLECULAR MEDICINE

Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells

(2017) Lin Wang et al.   Scientific Reports

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism

(2017) Aishwarya Sathyanarayan et al.   Cell Reports

Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum

(2016) Timothy Hardy et al.   Annual Review of Pathology-Mechanisms of Disease

Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

(2016) Martin D. Brand et al.   Cell Metabolism

A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice

(2016) Kelsey H. Fisher-Wellman et al.   DIABETES

Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment

(2016) Meric Erikci Ertunc et al.   JOURNAL OF LIPID RESEARCH

Mitofusins, from Mitochondria to Metabolism

(2016) Emilie Schrepfer et al.   MOLECULAR CELL

Mitochondrial Dynamics and Metabolic Regulation

(2016) Timothy Wai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of high fat diets on rodent liver bioenergetics and oxidative imbalance

(2016) Pâmela A. Kakimoto et al.   Redox Biology

Mitofusin 2 as a Driver That Controls Energy Metabolism and Insulin Signaling

(2015) Antonio Zorzano et al.   ANTIOXIDANTS & REDOX SIGNALING

The contributions of respiration and glycolysis to extracellular acid production

(2015) Shona A. Mookerjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice

(2015) Ahmed Bettaieb et al.   GASTROENTEROLOGY

Saturated phosphatidic acids mediate saturated fatty acid–induced vascular calcification and lipotoxicity

(2015) Masashi Masuda et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of mitochondrial morphology and function by stearoylation of TFR1

(2015) Deniz Senyilmaz et al.   NATURE

Suppressors of superoxide production from mitochondrial complex III

(2015) Adam L Orr et al.   Nature Chemical Biology

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

(2014) Robert A. Egnatchik et al.   Molecular Metabolism

Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake

(2013) Andrea del Campo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Palmitate-induced Activation of Mitochondrial Metabolism Promotes Oxidative Stress and Apoptosis in H4IIEC3 Rat Hepatocytes

(2013) Robert A. Egnatchik et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Pathophysiology of Human Visceral Obesity: An Update

(2013) André Tchernof et al.   PHYSIOLOGICAL REVIEWS

Diet-Sensitive Sources of Reactive Oxygen Species in Liver Mitochondria: Role of Very Long Chain Acyl-CoA Dehydrogenases

(2013) Ariel R. Cardoso et al.   PLoS One

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria

(2012) Akos A. Gerencser et al.   JOURNAL OF PHYSIOLOGY-LONDON

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Essential amino acids and glutamine regulate induction of mitochondrial elongation during autophagy

(2011) Ligia C. Gomes et al.   CELL CYCLE

Plasma Free Myristic Acid Proportion Is a Predictor of Nonalcoholic Steatohepatitis

(2011) Kengo Tomita et al.   DIGESTIVE DISEASES AND SCIENCES

Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle

(2011) H.-F. Jheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

(2010) Jianjun Bao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

(2010) Kuok Teong Ong et al.   HEPATOLOGY

Lipidomics reveals a remarkable diversity of lipids in human plasma,

(2010) Oswald Quehenberger et al.   JOURNAL OF LIPID RESEARCH

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Activation of NF-κB by Palmitate in Endothelial Cells

(2009) Ezekiel Maloney et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial Networking Protects  -Cells From Nutrient-Induced Apoptosis

(2009) A. J.A. Molina et al.   DIABETES

Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells

(2008) Rafael Herling Lambertucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY