Insulin resistance, cardiovascular stiffening and cardiovascular disease

Insulin- and Aldosterone-Mediated Signaling in Endothelial Cells Converge on SGK1 to Promote Endothelial Sodium Channel Activation

(2021) Michael A. Hill et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Endothelial sodium channel activation promotes cardiac stiffness and diastolic dysfunction in western diet fed female mice

(2020) James R. Sowers et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Dynamic Effects of Aortic Arch Stiffening on Pulsatile Energy Transmission to Cerebral Vasculature as A Determinant of Brain-Heart Coupling

(2020) Arian Aghilinejad et al.   Scientific Reports

Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling

(2020) Ranganath Muniyappa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age, Sex, and the Vascular Contributors to Cerebral Pulsatility and Pulsatile Damping

(2020) Wesley K. Lefferts et al.   JOURNAL OF APPLIED PHYSIOLOGY

Maternal Exposure to High Fructose and Offspring Health

(2019) Guanghong Jia et al.   HYPERTENSION

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

(2019) Ramachandran S. Vasan et al.   Journal of the American Heart Association

Epithelial sodium channels in endothelial cells mediate diet-induced endothelium stiffness and impaired vascular relaxation in obese female mice

(2019) James R. Sowers et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity

(2019) Zachary J. Ward et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors

(2018) Thomas R. Kleyman et al.   Annual Review of Physiology

Diabetic Cardiomyopathy

(2018) Guanghong Jia et al.   CIRCULATION RESEARCH

Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction

(2018) Guanghong Jia et al.   HYPERTENSION

Enhanced endothelium epithelial sodium channel signaling prompts left ventricular diastolic dysfunction in obese female mice

(2018) Guanghong Jia et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ascending Aortic Strain Analysis Using 2‐Dimensional Speckle Tracking Echocardiography Improves the Diagnostics for Coronary Artery Stenosis in Patients With Suspected Stable Angina Pectoris

(2018) Zhaohui Bu et al.   Journal of the American Heart Association

The endothelial αENaC contributes to vascular endothelial function in vivo

(2017) Antoine Tarjus et al.   PLoS One

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in FemalesNovelty and Significance

(2016) Guanghong Jia et al.   CIRCULATION RESEARCH

Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

(2015) Guanghong Jia et al.   Nature Reviews Endocrinology

Vascular stiffness in insulin resistance and obesity

(2015) Guanghong Jia et al.   Frontiers in Physiology

“Smooth Muscle Cell Stiffness Syndrome”—Revisiting the Structural Basis of Arterial Stiffness

(2015) Nancy L. Sehgel et al.   Frontiers in Physiology

Nanomechanics of vascular endothelium

(2014) Johannes Fels et al.   CELL AND TISSUE RESEARCH

Collecting Duct Principal Cell Transport Processes and Their Regulation

(2014) D. Pearce et al.   Clinical Journal of the American Society of Nephrology

Arterial Stiffness as a Risk Factor for Coronary Artery Disease

(2014) Josh Liao et al.   Current Atherosclerosis Reports

Pulse Pressure Relation to Aortic and Left Ventricular Structure in the Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study

(2014) Alyssa A. Torjesen et al.   HYPERTENSION

Endothelial Dysfunction Potentially Interacts With Impaired Glucose Metabolism to Increase Cardiovascular Risk

(2014) Guanghong Jia et al.   HYPERTENSION

Vasoactive agonists exert dynamic and coordinated effects on vascular smooth muscle cell elasticity, cytoskeletal remodelling and adhesion

(2014) Zhongkui Hong et al.   JOURNAL OF PHYSIOLOGY-LONDON

SGK1 is regulated by metabolic-related factors in 3T3-L1 adipocytes and overexpressed in the adipose tissue of subjects with obesity and diabetes

(2013) Ping Li et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Obesity and Insulin Resistance Induce Early Development of Diastolic Dysfunction in Young Female Mice Fed a Western Diet

(2013) Camila Manrique et al.   ENDOCRINOLOGY

Cardiovascular disease in childhood: the role of obesity

(2013) Despina Herouvi et al.   EUROPEAN JOURNAL OF PEDIATRICS

Arterial function and anatomy in obese children with cardiovascular risk factors

(2013) Baris Guven et al.   PEDIATRICS INTERNATIONAL

The role of ENaC in vascular endothelium

(2013) Kristina Kusche-Vihrog et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Role of insulin resistance in endothelial dysfunction

(2013) Ranganath Muniyappa et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Coordination of fibronectin adhesion with contraction and relaxation in microvascular smooth muscle

(2012) Zhongkui Hong et al.   CARDIOVASCULAR RESEARCH

Endothelial Insulin and IGF-1 Receptors: When Yes Means NO

(2012) R. Muniyappa et al.   DIABETES

Insulin resistance and arterial stiffness in healthy adolescents and young adults

(2011) E. M. Urbina et al.   DIABETOLOGIA

Arterial Stiffness is Strongly Associated with Insulin Resistance in Chinese —A Population-Based Study (Taichung Community Health Study, TCHS)

(2011) Chih-Te Ho et al.   Journal of Atherosclerosis and Thrombosis

The relationship between mechanical properties of carotid artery and coronary artery disease

(2011) S.-A. Kim et al.   European Heart Journal-Cardiovascular Imaging

Arterial Stiffness and Cardiovascular Events

(2010) Gary F. Mitchell et al.   CIRCULATION

Ultrasonographic strain imaging is superior to conventional non-invasive measures of vascular stiffness in the detection of age-dependent differences in the mechanical properties of the common carotid artery

(2010) A. Bjallmark et al.   European Journal of Echocardiography

Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness

(2010) Charalambos Vlachopoulos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY