The characteristics and the multiple functions of integrin β1 in human cancers
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The characteristics and the multiple functions of integrin β1 in human cancers
Authors
Keywords
-
Journal
Journal of Translational Medicine
Volume 21, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-11-07
DOI
10.1186/s12967-023-04696-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism
- (2023) Michele Anselmi et al. Journal of Medicinal Chemistry
- Buddlejasaponin IV induces apoptotic cell death by activating the mitochondrial‑dependent apoptotic pathway and reducing α2β1 integrin‑mediated adhesion in HT‑29 human colorectal cancer cells
- (2023) Jin-Eun Kim et al. ONCOLOGY REPORTS
- LINC01798/miR-17-5p axis regulates ITGA8 and causes changes in tumor microenvironment and stemness in lung adenocarcinoma
- (2023) Xuanguang Li et al. Frontiers in Immunology
- Endostatin 33 Peptide Is a Deintegrin α6β1 Agent That Exerts Antitumor Activity by Inhibiting the PI3K-Akt Signaling Pathway in Prostate Cancer
- (2023) Yang Liu et al. Journal of Clinical Medicine
- Combination Therapy with a Bispecific Antibody Targeting the hERG1/β1 Integrin Complex and Gemcitabine in Pancreatic Ductal Adenocarcinoma
- (2023) Tiziano Lottini et al. Cancers
- The Extracellular Matrix: Its Composition, Function, Remodeling, and Role in Tumorigenesis
- (2023) Kevin Dzobo et al. Biomimetics
- Evaluation of ITGB1 expression as a predictor of the therapeutic effects of immune checkpoint inhibitors in gastric cancer
- (2023) Chao Xu et al. BMC GASTROENTEROLOGY
- Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities
- (2023) Siyi Li et al. Cell Communication and Signaling
- Dysregulated Signalling Pathways Driving Anticancer Drug Resistance
- (2023) Nauf Bou Antoun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chenodeoxycholic acid inhibits lung adenocarcinoma progression via the integrin α5β1/FAK/p53 signaling pathway
- (2022) Dan Shen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mucin 5AC–Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate Pancreatic Cancer Stromal Heterogeneity
- (2022) Koelina Ganguly et al. GASTROENTEROLOGY
- Alternagin-C, an alpha2beta1 integrin ligand, attenuates collagen-based adhesion, stimulating the metastasis suppressor 1 expression in triple-negative breast tumor cells
- (2022) Milene Nóbrega de Oliveira Moritz et al. TOXICON
- Integrin α2 and β1 Cross-Communication with mTOR/AKT and the CDK-Cyclin Axis in Hepatocellular Carcinoma Cells
- (2022) Mazen A. Juratli et al. Cancers
- Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis
- (2022) Eunnyung Bae et al. Nature Communications
- Integrin β1 in Pancreatic Cancer: Expressions, Functions, and Clinical Implications
- (2022) Jiajia Li et al. Cancers
- Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis
- (2022) Guillermo A. Martínez-Nieto et al. Frontiers in Oncology
- αvβ1 integrin is enriched in extracellular vesicles of metastatic breast cancer cells: A mechanism mediated by galectin‐3
- (2022) Daniel Xin Zhang et al. Journal of Extracellular Vesicles
- Chemotherapy treatment induces pro-invasive changes in liver ECM composition
- (2022) Justinne R. Guarin et al. MATRIX BIOLOGY
- DNA Aptamer Selected against Esophageal Squamous Cell Carcinoma for Tissue Imaging and Targeted Therapy with Integrin β1 as a Molecular Target
- (2022) Yangyang Zhang et al. Analytical Chemistry
- Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance
- (2021) Hassan Yousefi et al. ONCOGENE
- Integrin α3β1 Promotes Invasive and Metastatic Properties of Breast Cancer Cells through Induction of the Brn-2 Transcription Factor
- (2021) Rakshitha Pandulal Miskin et al. Cancers
- Integrin α3β1 Represses Reelin Expression in Breast Cancer Cells to Promote Invasion
- (2021) Abibatou Ndoye et al. Cancers
- Integrin α10-Antibodies Reduce Glioblastoma Tumor Growth and Cell Migration
- (2021) Katarzyna Chmielarska Masoumi et al. Cancers
- Integrin α2β1 Represents a Prognostic and Predictive Biomarker in Primary Ovarian Cancer
- (2021) Katharina Dötzer et al. Biomedicines
- Interaction between Galectin-3 and Integrins Mediates Cell-Matrix Adhesion in Endothelial Cells and Mesenchymal Stem Cells
- (2021) Antonín Sedlář et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Implication of integrin α2β1 in senescence of SK-Mel-147 human melanoma cells
- (2021) Nadezhda I. Kozlova et al. Aging-US
- Characteristics of TIMP1, CD63, and β1-Integrin and the Functional Impact of Their Interaction in Cancer
- (2021) Beatriz Laís Justo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Higher Integrin Alpha 3 Beta1 Expression in Papillary Thyroid Cancer Is Associated with Worst Outcome
- (2021) Lorenza Mautone et al. Cancers
- Integrin α5 mediates cancer cell-fibroblast adhesion and peritoneal dissemination of diffuse-type gastric carcinoma
- (2021) Shingo Miyamoto et al. CANCER LETTERS
- Loss of Integrin α9β1 on Tumor Keratinocytes Enhances the Stromal Vasculature and Growth of Cutaneous Tumors
- (2021) Scott D. Varney et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- ITGB1 Drives Hepatocellular Carcinoma Progression by Modulating Cell Cycle Process Through PXN/YWHAZ/AKT Pathways
- (2021) Jinghe Xie et al. Frontiers in Cell and Developmental Biology
- Heat Shock Cognate Protein 70 Enhanced Integrin β1 Mediated Invasion in Cancer Cells
- (2020) Guan Sun et al. Cancer Management and Research
- α3β1 Integrin-Targeting Polymersomal Docetaxel as an Advanced Nanotherapeutic for Nonsmall Cell Lung Cancer Treatment
- (2020) Yan Zou et al. ACS Applied Materials & Interfaces
- β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters
- (2020) Fabian Baltes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- VLA-4 Expression and Activation in B Cell Malignancies: Functional and Clinical Aspects
- (2020) Andrea Härzschel et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Aberrantly glycosylated integrin α3β1 is a unique urinary biomarker for the diagnosis of bladder cancer
- (2020) Di Jin et al. Aging-US
- Tenascin-C Induces Phenotypic Changes in Fibroblasts to Myofibroblasts with High Contractility through the Integrin αvβ1/Transforming Growth Factor β/SMAD Signaling Axis in Human Breast Cancer
- (2020) Daisuke Katoh et al. AMERICAN JOURNAL OF PATHOLOGY
- Localization of integrin heterodimer α9β1 on the surface of uterine endometrial stromal and epithelial cells in mice
- (2020) Hye Jin Park et al. Animal Cells and Systems
- Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance
- (2020) Tomoyuki Uchihara et al. CANCER RESEARCH
- Laminins in osteogenic differentiation and pluripotency maintenance
- (2020) Chaozhen Chen et al. DIFFERENTIATION
- CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity
- (2020) Julia C. Gutjahr et al. HAEMATOLOGICA
- Upregulated expression and function of the α 4 β 1 integrin in multiple myeloma cells resistant to bortezomib
- (2020) Silvia Sevilla‐Movilla et al. JOURNAL OF PATHOLOGY
- Androgen receptor-induced integrin α6β1 and Bnip3 promote survival and resistance to PI3K inhibitors in castration-resistant prostate cancer
- (2020) Eric A. Nollet et al. ONCOGENE
- Epigenetic Input Dictates the Threshold of Targeting of the Integrin-Dependent Pathway in Non-small Cell Lung Cancer
- (2020) Yang Zhang et al. Frontiers in Cell and Developmental Biology
- Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis
- (2020) Veronika Ramovs et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Reciprocal Interplay Between Fibrillar Collagens and Collagen-Binding Integrins: Implications in Cancer Progression and Metastasis
- (2020) Isabelle Bourgot et al. Frontiers in Oncology
- β1 and β2 integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation
- (2020) Ziwei Ou et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Integrin α2β1 inhibition attenuates prostate cancer cell proliferation by cell cycle arrest, promoting apoptosis and reducing epithelial–mesenchymal transition
- (2020) Zahra Salemi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review
- (2019) Hiroshi Yasuda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Keratinocyte integrin α3β1 promotes secretion of IL-1α to effect paracrine regulation of fibroblast gene expression and differentiation
- (2019) Rui Zheng et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Integrin α9 depletion promotes β‐catenin degradation to suppress triple‐negative breast cancer tumor growth and metastasis
- (2019) Zhishan Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival
- (2019) Matilda Munksgaard Thorén et al. Cancers
- Correlation of integrin alpha 7 with clinicopathological characteristics and survival profiles, as well as its regulatory role in cell proliferation, apoptosis, and stemness in non‐small‐cell lung cancer
- (2019) Dongping Xia et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Integrin heterodimer α 9 β 1 is localized on the surface of porcine spermatogonial stem cells in the undifferentiated state
- (2019) Min Hee Park et al. REPRODUCTION IN DOMESTIC ANIMALS
- Integrin α7 correlates with worse clinical features and prognosis, and its knockdown inhibits cell proliferation and stemness in tongue squamous cell carcinoma
- (2019) Zhiyong Lv et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Integrin α7 is overexpressed and correlates with higher pathological grade, increased T stage, advanced TNM stage as well as worse survival in clear cell renal cell carcinoma patients: A retrospective study
- (2019) Yue Chen et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Prognostic value of increased integrin-beta 1 expression in solid cancers: a meta-analysis
- (2018) Quanwu Sun et al. OncoTargets and Therapy
- Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling
- (2018) Yan-Li Zhang et al. Journal of Immunology Research
- Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer
- (2017) Arman Jahangiri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by β1 integrin/JNK co-targeting
- (2017) Anne Vehlow et al. Oncotarget
- Involvement of the Integrin α1β1 in the Progression of Colorectal Cancer
- (2017) Salah Boudjadi et al. Cancers
- Inhibition of Ovarian Tumor Growth by Targeting the HU177 Cryptic Collagen Epitope
- (2016) Jennifer M. Caron et al. AMERICAN JOURNAL OF PATHOLOGY
- Molecular Basis of the Ligand Binding Specificity of αvβ8 Integrin
- (2016) Akio Ozawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Highly Expressed Integrin-α8 Induces Epithelial to Mesenchymal Transition-Like Features in Multiple Myeloma with Early Relapse
- (2016) Jiyeon Ryu et al. MOLECULES AND CELLS
- Integrin-based therapeutics: biological basis, clinical use and new drugs
- (2016) Klaus Ley et al. NATURE REVIEWS DRUG DISCOVERY
- Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
- (2016) Xiao-Yan Ming et al. Nature Communications
- Integrin- 10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma
- (2016) T. Okada et al. Cancer Discovery
- The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
- (2016) Anette M. Høye et al. Scientific Reports
- LAMC2 enhances the metastatic potential of lung adenocarcinoma
- (2015) Y W Moon et al. CELL DEATH AND DIFFERENTIATION
- hTERT promotes the invasion of gastric cancer cells by enhancing FOXO3a ubiquitination and subsequent ITGB1 upregulation
- (2015) Changjiang Hu et al. GUT
- Simultaneous β1 integrin-EGFR Targeting and Radiosensitization of Human Head and Neck Cancer
- (2015) Iris Eke et al. JNCI-Journal of the National Cancer Institute
- Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer
- (2015) R Navab et al. ONCOGENE
- Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells
- (2015) E Dickreuter et al. ONCOGENE
- Integrin α1β1 expression is controlled by c-MYC in colorectal cancer cells
- (2015) S Boudjadi et al. ONCOGENE
- Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data
- (2015) TEOW KOK-SIN et al. ONCOLOGY REPORTS
- ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients
- (2015) Xiaolin Lu et al. TUMOR BIOLOGY
- Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma
- (2015) Imran Nawaz et al. Oncotarget
- Simultaneous β1 integrin-EGFR Targeting and Radiosensitization of Human Head and Neck Cancer
- (2015) Iris Eke et al. JNCI-Journal of the National Cancer Institute
- Inhibition of α4β1 integrin increases ovarian cancer response to carboplatin
- (2014) Jennifer M. Scalici et al. GYNECOLOGIC ONCOLOGY
- Correlation between Beta1 integrin expression and prognosis in clinically localized prostate cancer
- (2014) Jose Pontes-Junior et al. International Braz J Urol
- Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis
- (2013) R A Bartolomé et al. ONCOGENE
- β1 Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy
- (2012) Iris Eke et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrin α9β1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition
- (2012) S K Gupta et al. ONCOGENE
- Increased Expression Levels of Integrin α9β1 and CD11b on Circulating Neutrophils and Elevated Serum IL-17A in Elderly Aspiration Pneumonia
- (2012) Yasuyuki Taooka et al. RESPIRATION
- α9β1 integrin engagement inhibits neutrophil spontaneous apoptosis: Involvement of Bcl-2 family members
- (2010) Roberta F. Saldanha-Gama et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Integrins as therapeutic targets: lessons and opportunities
- (2010) Dermot Cox et al. NATURE REVIEWS DRUG DISCOVERY
- TGFβ: a sleeping giant awoken by integrins
- (2010) John J. Worthington et al. TRENDS IN BIOCHEMICAL SCIENCES
- Integrins
- (2009) Malgorzata Barczyk et al. CELL AND TISSUE RESEARCH
- α9β1 Integrin in melanoma cells can signal different adhesion states for migration and anchorage
- (2009) Magnus C. Lydolph et al. EXPERIMENTAL CELL RESEARCH
- The integrin 9 1 on hematopoietic stem and progenitor cells: involvement in cell adhesion, proliferation and differentiation
- (2009) T. D. Schreiber et al. HAEMATOLOGICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now