Integrin α2 and β1 Cross-Communication with mTOR/AKT and the CDK-Cyclin Axis in Hepatocellular Carcinoma Cells

Clinical implications and molecular mechanisms of Cyclin-dependent kinases 4 for patients with hepatocellular carcinoma

(2022) Zhong-liu Wei et al.   BMC GASTROENTEROLOGY

Insulin-like Growth Factor-1 Influences Prostate Cancer Cell Growth and Invasion through an Integrin α3, α5, αV, and β1 Dependent Mechanism

(2022) Carolin Siech et al.   Cancers

SPC25 promotes hepatocellular carcinoma metastasis via activating the FAK/PI3K/AKT signaling pathway through ITGB4

(2022) Wen-Kai Shi et al.   ONCOLOGY REPORTS

Treatment of RB1‐intact hepatocellular carcinoma with CDK4/6 inhibitor combination therapy

(2021) Jindan Sheng et al.   HEPATOLOGY

A Starvation-Based 9-mRNA Signature Correlates With Prognosis in Patients With Hepatocellular Carcinoma

(2021) Dengliang Lei et al.   Frontiers in Oncology

The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis

(2020) Yanli Liu et al.   Aging-US

Role of the mTOR pathway in liver cancer: from molecular genetics to targeted therapies

(2020) Xinjun Lu et al.   HEPATOLOGY

ZKSCAN3 drives tumor metastasis via integrin β4/FAK/AKT mediated epithelial–mesenchymal transition in hepatocellular carcinoma

(2020) Jieqiong Li et al.   Cancer Cell International

THBS4 promotes HCC progression by regulating ITGB1 via FAK/PI3K/AKT pathway

(2020) Dan Guo et al.   FASEB JOURNAL

rAj-Tspin, a novel recombinant peptide from Apostichopus japonicus, suppresses the proliferation, migration, and invasion of BEL-7402 cells via a mechanism associated with the ITGB1-FAK-AKT pathway

(2020) Ping Yu et al.   INVESTIGATIONAL NEW DRUGS

Inhibition of p70 isoforms of S6K1 induces anoikis to prevent transformed human hepatocyte growth

(2020) Tapas Patra et al.   LIFE SCIENCES

lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinoma

(2019) Fan Wang et al.   Cancer Management and Research

Interleukin-8 promotes integrin β3 upregulation and cell invasion through PI3K/Akt pathway in hepatocellular carcinoma

(2019) Fengkai Sun et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Integrin alpha 7 correlates with poor clinical outcomes, and it regulates cell proliferation, apoptosis and stemness via PTK2-PI3K-Akt signaling pathway in hepatocellular carcinoma

(2019) Jun-Chen Ge et al.   CELLULAR SIGNALLING

Cell adhesion is regulated by CDK1 during the cell cycle

(2018) Matthew C. Jones et al.   JOURNAL OF CELL BIOLOGY

β1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway

(2018) Tao Tian et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

HDAC Inhibition Counteracts Metastatic Re-Activation of Prostate Cancer Cells Induced by Chronic mTOR Suppression

(2018) Jasmina Makarević et al.   Cells

Bioinformatics analysis of gene expression alterations in microRNA-122 knockout mice with hepatocellular carcinoma

(2017) Bosheng He et al.   Molecular Medicine Reports

Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin β1/FAK signaling pathway in nonalcoholic fatty liver

(2017) Xinglong Zheng et al.   Oncotarget

An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK–AKT pathway

(2016) Chao Leng et al.   CANCER LETTERS

Immediate early response protein 2 regulates hepatocellular carcinoma cell adhesion and motility via integrin β1-mediated signaling pathway

(2016) Zhengxin Xu et al.   ONCOLOGY REPORTS

Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

(2016) Kwong-Fai Wong et al.   Oncotarget

Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells

(2016) Yang You et al.   Oncotarget

Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin β1

(2014) Yinying Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vimentin phosphorylation by Cdc2 in Schwann cell controls axon growth via β1-integrin activation

(2012) In Ae Chang et al.   FASEB JOURNAL

Targeting integrins in hepatocellular carcinoma

(2011) Yanhua Wu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response

(2011) Y-H Lee et al.   ONCOGENE

Role of mTOR in anticancer drug resistance: Perspectives for improved drug treatment

(2008) Bing-Hua Jiang et al.   DRUG RESISTANCE UPDATES