ATF4 Protein Deficiency Protects against High Fructose-induced Hypertriglyceridemia in Mice

Central Activating Transcription Factor 4 (ATF4) Regulates Hepatic Insulin Resistance in Mice via S6K1 Signaling and the Vagus Nerve

(2013) Q. Zhang et al.   DIABETES

FoxO1 Protein Cooperates with ATF4 Protein in Osteoblasts to Control Glucose Homeostasis

(2012) Aruna Kode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATF4 deficiency protects mice from high-carbohydrate-diet-induced liver steatosis

(2011) Houkai Li et al.   BIOCHEMICAL JOURNAL

FoxO1 integrates insulin signaling to VLDL production

(2011) Adama Kamagate et al.   CELL CYCLE

FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver

(2011) Dae Hyun Kim et al.   DIABETES

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

(2011) Eva Morán-Salvador et al.   FASEB JOURNAL

Up-Regulation of PPAR-γ mRNA Expression in the Liver of Obese Patients: an Additional Reinforcing Lipogenic Mechanism to SREBP-1c Induction

(2011) Paulina Pettinelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance

(2011) Sung Hee Choi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

ATF4 regulates lipid metabolism and thermogenesis

(2010) Chunxia Wang et al.   CELL RESEARCH

Activating transcription factor 4 regulates osteoclast differentiation in mice

(2010) Huiling Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Fructose induced lipogenesis: from sugar to fat to insulin resistance

(2010) Varman T. Samuel   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes

(2009) Kim-Anne Lê et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure

(2009) J. Seo et al.   DIABETES

The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts

(2009) Tatsuya Yoshizawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

(2009) Kimber L. Stanhope et al.   JOURNAL OF CLINICAL INVESTIGATION

Critical Role of Activating Transcription Factor 4 in the Anabolic Actions of Parathyroid Hormone in Bone

(2009) Shibing Yu et al.   PLoS One

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Parathyroid Hormone Increases Activating Transcription Factor 4 Expression and Activity in Osteoblasts: Requirement forOsteocalcinGene Expression

(2008) Shibing Yu et al.   ENDOCRINOLOGY

Activating transcription factor 4 is critical for proliferation and survival in primary bone marrow stromal cells and calvarial osteoblasts

(2008) Xiaoyan Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION

The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism

(2008) Henry N. Ginsberg et al.   JOURNAL OF LIPID RESEARCH

Proteomic analysis of fructose-induced fatty liver in hamsters

(2008) Lihe Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The many intersecting pathways underlying apolipoprotein B secretion and degradation

(2008) Jeffrey L. Brodsky et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

(2007) Jie Zhou et al.   GASTROENTEROLOGY