Synaptotagmin‐11 regulates immune functions of microglia in vivo

The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease

(2021) Katja Badanjak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synaptotagmin‐11 inhibits spontaneous neurotransmission through vti1a

(2021) Wan‐Ru Li et al.   JOURNAL OF NEUROCHEMISTRY

Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation

(2020) Xueying Tian et al.   EMBO JOURNAL

Microglia, Lifestyle Stress, and Neurodegeneration

(2020) Charlotte Madore et al.   IMMUNITY

Membrane trafficking in health and disease

(2020) Rebecca Yarwood et al.   Disease Models & Mechanisms

Similar microglial cell densities across brain structures and mammalian species: Implications for brain tissue function

(2020) Sandra E. Dos Santos et al.   JOURNAL OF NEUROSCIENCE

The diversity of synaptotagmin isoforms

(2020) Anne C Wolfes et al.   CURRENT OPINION IN NEUROBIOLOGY

Pathogenic Mutations Differentially Regulate Cell-to-Cell Transmission of α-Synuclein

(2020) Yuan Guan et al.   Frontiers in Cellular Neuroscience

Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity

(2019) Masafumi Shimojo et al.   GENES & DEVELOPMENT

Ischemic preconditioning induces cortical microglial proliferation and a transcriptomic program of robust cell cycle activation

(2019) Ashley McDonough et al.   GLIA

Synaptotagmin‐11 regulates the functions of caveolae and responds to mechanical stimuli in astrocytes

(2019) Shuxin Yan et al.   FASEB JOURNAL

Intrastriatal injection of preformed alpha-synuclein fibrils alters central and peripheral immune cell profiles in non-transgenic mice

(2019) Rachael H. Earls et al.   Journal of Neuroinflammation

Endosomal and Phagosomal SNAREs

(2018) Ilse Dingjan et al.   PHYSIOLOGICAL REVIEWS

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson’s disease-like pathology

(2018) Changhe Wang et al.   Nature Communications

Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi

(2018) Javier Emperador-Melero et al.   Nature Communications

Vti Proteins: Beyond Endolysosomal Trafficking

(2018) Javier Emperador-Melero et al.   NEUROSCIENCE

Synaptotagmin-11 inhibits cytokine secretion and phagocytosis in microglia

(2017) Cuilian Du et al.   GLIA

Microglial phenotypes in Parkinson’s disease and animal models of the disease

(2017) Valerie Joers et al.   PROGRESS IN NEUROBIOLOGY

SNARE proteins in membrane trafficking

(2017) Tuanlao Wang et al.   TRAFFIC

Synaptotagmin XI in Parkinson's disease: New evidence from an association study in Spain and Mexico

(2016) Angel Sesar et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Parkinson’s disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway

(2016) Carla F. Bento et al.   Nature Communications

Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis

(2015) S C Sreetama et al.   CELL DEATH AND DIFFERENTIATION

Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis

(2015) C. Wang et al.   EMBO REPORTS

Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic β-cells

(2014) Alexandra Milochau et al.   FEBS LETTERS

Synaptotagmin XI Regulates Phagocytosis and Cytokine Secretion in Macrophages

(2013) G. Arango Duque et al.   JOURNAL OF IMMUNOLOGY

Supportive evidence for 11 loci from genome-wide association studies in Parkinson's disease

(2012) Lasse Pihlstrøm et al.   NEUROBIOLOGY OF AGING

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development

(2011) A. J. Kunwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models

(2010) Sungho Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion

(2009) Natalia Gustavsson et al.   BIOSCIENCE REPORTS

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Differential mRNA expression patterns of the synaptotagmin gene family in the rodent brain

(2008) Tobias Mittelsteadt et al.   JOURNAL OF COMPARATIVE NEUROLOGY

SNAREing the Basis of Multicellularity: Consequences of Protein Family Expansion during Evolution

(2008) T. H. Kloepper et al.   MOLECULAR BIOLOGY AND EVOLUTION