Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation

Tumorigenic Activity of Merkel Cell Polyomavirus T Antigens Expressed in the Stratified Epithelium of Mice

(2015) M. E. Spurgeon et al.   CANCER RESEARCH

The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma

(2015) Paul William Harms et al.   CANCER RESEARCH

Translational Implications of Tumor Heterogeneity

(2015) M. Jamal-Hanjani et al.   CLINICAL CANCER RESEARCH

Merkel cell carcinoma: histopathologic and prognostic features according to the immunohistochemical expression of Merkel cell polyomavirus large T antigen correlated with viral load

(2015) Valérie Leroux-Kozal et al.   HUMAN PATHOLOGY

Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses

(2015) Paul W. Harms et al.   HUMAN PATHOLOGY

Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic Mice

(2015) Monique E. Verhaegen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cutaneous squamous and neuroendocrine carcinoma: genetically and immunohistochemically different from Merkel cell carcinoma

(2015) Melissa P Pulitzer et al.   MODERN PATHOLOGY

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Large T and small T antigens of Merkel cell polyomavirus

(2015) Justin A Wendzicki et al.   Current Opinion in Virology

Loss of Cytokeratin 20 and Acquisition of Thyroid Transcription Factor-1 Expression in a Merkel Cell Carcinoma Metastasis to the Brain

(2014) Sara C. Shalin et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Identification of a melanoma susceptibility locus and somatic mutation inTET2

(2014) Fengju Song et al.   CARCINOGENESIS

Merkel Cell Carcinoma Dependence on Bcl-2 Family Members for Survival

(2014) Monique E. Verhaegen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cytokeratin 20-negative Merkel cell carcinoma is infrequently associated with the Merkel cell polyomavirus

(2014) Andrew G Miner et al.   MODERN PATHOLOGY

Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma

(2014) Patrick J Cimino et al.   MODERN PATHOLOGY

EZH2: Not EZHY (Easy) to Deal

(2014) Gauri Deb et al.   MOLECULAR CANCER RESEARCH

UV Signature Mutations

(2014) Douglas E. Brash   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Tumor evolution and progression in multifocal and paired non-invasive/invasive urothelial carcinoma

(2014) Joshua I. Warrick et al.   VIRCHOWS ARCHIV

Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention

(2014) Song Poon et al.   Genome Medicine

Small cell carcinoma in the parotid harboring Merkel cell polyomavirus

(2014) Clayton A. Fisher et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

Expression of focal TTF-1 expression in a case of CK7/CK20-positive Merkel cell carcinoma

(2013) Deepti M. Reddi et al.   JOURNAL OF CUTANEOUS PATHOLOGY

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

(2013) E Solary et al.   LEUKEMIA

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Activation of PI3K Signaling in Merkel Cell Carcinoma

(2012) Valentina Nardi et al.   CLINICAL CANCER RESEARCH

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

(2012) Wenqing Fu et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

(2012) Charles M Rudin et al.   NATURE GENETICS

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

(2012) Martin Peifer et al.   NATURE GENETICS

Tumours associated with BAP1 mutations

(2012) Rajmohan Murali et al.   PATHOLOGY

Merkel Cell Carcinoma: A Virus-Induced Human Cancer

(2011) Yuan Chang et al.   Annual Review of Pathology-Mechanisms of Disease

Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma

(2011) H. Sihto et al.   CLINICAL CANCER RESEARCH

Immunohistochemistry for Merkel cell polyomavirus is highly specific but not sensitive for the diagnosis of Merkel cell carcinoma in the Australian population

(2011) Julie Y. Paik et al.   HUMAN PATHOLOGY

The spectrum of Merkel cell polyomavirus expression in Merkel cell carcinoma, in a variety of cutaneous neoplasms, and in neuroendocrine carcinomas from different anatomical sites

(2011) Thai Yen Ly et al.   HUMAN PATHOLOGY

Merkel cell carcinoma with cytokeratin 20-negative and thyroid transcription factor-1-positive immunostaining admixed with squamous cell carcinoma

(2011) Shinichi Koba et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Germline mutations in BAP1 predispose to melanocytic tumors

(2011) Thomas Wiesner et al.   NATURE GENETICS

Germline BAP1 mutations predispose to malignant mesothelioma

(2011) Joseph R Testa et al.   NATURE GENETICS

EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas

(2011) Russell J. H. Ryan et al.   PLoS One

Merkel Cell Carcinoma

(2009) Melissa P. Pulitzer et al.   ADVANCES IN ANATOMIC PATHOLOGY

Merkel Cell Polyomavirus Expression in Merkel Cell Carcinomas and Its Absence in Combined Tumors and Pulmonary Neuroendocrine Carcinomas

(2009) Klaus J. Busam et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Array-CGH Reveals Recurrent Genomic Changes in Merkel Cell Carcinoma Including Amplification of L-Myc

(2008) Kelly G. Paulson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

(2008) M. Shuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma

(2008) H. Feng et al.   SCIENCE