Identification of a melanoma susceptibility locus and somatic mutation inTET2

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

(2015) Michael Christoph Haffner et al.   Oncotarget

Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors

(2014) Allison R Larson et al.   MODERN PATHOLOGY

5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi

(2013) Ryuhei Uchiyama et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma

(2013) Thilo Gambichler et al.   MELANOMA RESEARCH

Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis

(2013) Emily F Mason et al.   MODERN PATHOLOGY

Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1

(2013) Chungang Liu et al.   PLoS One

HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis

(2013) M. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantification of the sixth DNA base 5-hydroxymethylcytosine in colorectal cancer tissue and C-26 cell line

(2013) Liang-Tao Zhang et al.   Bioanalysis

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

(2012) Christine Guo Lian et al.   CELL

Low values of 5-hydroxymethylcytosine (5hmC), the “sixth base,” are associated with anaplasia in human brain tumors

(2012) Theo F.J. Kraus et al.   INTERNATIONAL JOURNAL OF CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genome-wide association study identifies nidogen 1 ( NID1 ) as a susceptibility locus to cutaneous nevi and melanoma risk

(2011) Hongmei Nan et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma

(2011) Hongmei Nan et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma†

(2011) Christopher I. Amos et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies three new melanoma susceptibility loci

(2011) Jennifer H Barrett et al.   NATURE GENETICS

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

(2011) Stuart MacGregor et al.   NATURE GENETICS

Genetic variants in telomere-maintaining genes and skin cancer risk

(2010) Hongmei Nan et al.   HUMAN GENETICS

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Epidemiology of invasive cutaneous melanoma

(2009) R. M. MacKie et al.   ANNALS OF ONCOLOGY

Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms

(2009) C. Saint-Martin et al.   BLOOD

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

(2009) O. Abdel-Wahab et al.   BLOOD

Genetic risk factors for melanoma

(2009) Kathrine Damm Meyle et al.   HUMAN GENETICS

Multiple Pigmentation Gene Polymorphisms Account for a Substantial Proportion of Risk of Cutaneous Malignant Melanoma

(2009) David L. Duffy et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi

(2009) Mario Falchi et al.   NATURE GENETICS

Genome-wide association study identifies three loci associated with melanoma risk

(2009) D Timothy Bishop et al.   NATURE GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Moderate- to low-risk variant alleles of cutaneous malignancies and nevi: lessons from genome-wide association studies

(2009) Durga Udayakumar et al.   Genome Medicine

Genetics of melanoma predisposition

(2008) J. Lin et al.   BRITISH JOURNAL OF DERMATOLOGY

Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits

(2008) Simon N Stacey et al.   NATURE GENETICS

Common sequence variants on 20q11.22 confer melanoma susceptibility

(2008) Kevin M Brown et al.   NATURE GENETICS

ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS