CRISPR screening in hematology research: from bulk to single-cell level
Published 2023 View Full Article
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Title
CRISPR screening in hematology research: from bulk to single-cell level
Authors
Keywords
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Journal
Journal of Hematology & Oncology
Volume 16, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-24
DOI
10.1186/s13045-023-01495-5
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Note: Only part of the references are listed.- A transcription factor atlas of directed differentiation
- (2023) Julia Joung et al. CELL
- Predicting cellular responses to complex perturbations in high‐throughput screens
- (2023) Mohammad Lotfollahi et al. Molecular Systems Biology
- Microfluidics-free single-cell genomics with templated emulsification
- (2023) Iain C. Clark et al. NATURE BIOTECHNOLOGY
- Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens
- (2023) John A. Morris et al. SCIENCE
- Massively parallel phenotyping of coding variants in cancer with Perturb-seq
- (2022) Oana Ursu et al. NATURE BIOTECHNOLOGY
- Pooled genetic perturbation screens with image-based phenotypes
- (2022) David Feldman et al. Nature Protocols
- Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade
- (2022) Hanying Wang et al. BLOOD
- Spatial CRISPR genomics identifies regulators of the tumor microenvironment
- (2022) Maxime Dhainaut et al. CELL
- Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
- (2022) Julia A. Belk et al. CANCER CELL
- Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
- (2022) Joseph M. Replogle et al. CELL
- Live-seq enables temporal transcriptomic recording of single cells
- (2022) Wanze Chen et al. NATURE
- Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq
- (2022) Hans-Hermann Wessels et al. NATURE METHODS
- A balanced measure shows superior performance of pseudobulk methods in single-cell RNA-sequencing analysis
- (2022) Alan E. Murphy et al. Nature Communications
- Advanced single-cell pooled CRISPR screening identifies C19orf53 required for cell proliferation based on mTORC1 regulators
- (2021) Yulong Tang et al. CELL BIOLOGY AND TOXICOLOGY
- Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens
- (2021) Efthymia Papalexi et al. NATURE GENETICS
- Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion
- (2021) Chris J. Frangieh et al. NATURE GENETICS
- Combinatorial CRISPR screen identifies fitness effects of gene paralogues
- (2021) Nicola A. Thompson et al. Nature Communications
- Evaluating Capture Sequence Performance for Single-Cell CRISPR Activation Experiments
- (2021) Xin Yi Choo et al. ACS Synthetic Biology
- Decoding Neuronal Diversification by Multiplexed Single-cell RNA-Seq
- (2021) Joachim Luginbühl et al. Stem Cell Reports
- Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens
- (2021) Noa Liscovitch-Brauer et al. NATURE BIOTECHNOLOGY
- BTK inhibition sensitizes Acute Lymphoblastic Leukemia to asparaginase by suppressing the Amino Acid Response pathway
- (2021) Miriam Butler et al. BLOOD
- Genome wide CRISPR screening reveals a role for sialylation in the tumorigenesis and chemoresistance of acute myeloid leukemia cells
- (2021) Dong-hee Lee et al. CANCER LETTERS
- Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine
- (2021) Guotong Fu et al. NATURE
- Ultra-high-throughput single-cell RNA sequencing and perturbation screening with combinatorial fluidic indexing
- (2021) Paul Datlinger et al. NATURE METHODS
- Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
- (2021) Ruilin Tian et al. NATURE NEUROSCIENCE
- In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
- (2021) Meiou Dai et al. Nature Communications
- High-resolution characterization of gene function using single-cell CRISPR tiling screen
- (2021) Lu Yang et al. Nature Communications
- High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer
- (2021) Sarah E. Pierce et al. Nature Communications
- Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in Adult T-cell leukemia/lymphoma
- (2021) Takashi Ishio et al. BLOOD
- Functional single-cell genomics of human cytomegalovirus infection
- (2021) Marco Y. Hein et al. NATURE BIOTECHNOLOGY
- Joint single-cell measurements of nuclear proteins and RNA in vivo
- (2021) Hattie Chung et al. NATURE METHODS
- KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs
- (2021) Fangxue Yan et al. Cancer Discovery
- High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells
- (2020) Hui Kwon Kim et al. Nature Biomedical Engineering
- Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
- (2020) Theodore L. Roth et al. CELL
- Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing
- (2020) Joseph M. Replogle et al. NATURE BIOTECHNOLOGY
- Targeted Perturb-seq enables genome-scale genetic screens in single cells
- (2020) Daniel Schraivogel et al. NATURE METHODS
- Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
- (2020) Yonatan Katzenelenbogen et al. CELL
- Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
- (2020) Andrew V. Anzalone et al. NATURE BIOTECHNOLOGY
- A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets
- (2020) Peng Zhou et al. Cell Reports
- A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program
- (2020) Celia Alda-Catalinas et al. Cell Systems
- CRISPR screen identifies genes that sensitize AML cells to double negative T cell therapy
- (2020) Fraser Soares et al. BLOOD
- Genome-wide CRISPR screen identifies regulators of MAPK and MTOR pathways mediating sorafenib resistance in acute myeloid leukemia
- (2020) Alisa Damnernsawad et al. HAEMATOLOGICA
- HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes
- (2020) Jamie L. Marshall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes
- (2020) Xin Jin et al. SCIENCE
- A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens
- (2019) Molly Gasperini et al. CELL
- Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
- (2019) Benjamin P. Kleinstiver et al. NATURE BIOTECHNOLOGY
- Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
- (2019) Chee-Huat Linus Eng et al. NATURE
- Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells
- (2019) Eleni P. Mimitou et al. NATURE METHODS
- The next generation of CRISPR–Cas technologies and applications
- (2019) Adrian Pickar-Oliver et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
- (2019) Ryan M.J. Genga et al. Cell Reports
- Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis
- (2019) Chunyu Liao et al. Nature Communications
- Model-based understanding of single-cell CRISPR screening
- (2019) Bin Duan et al. Nature Communications
- Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
- (2019) Romain Guièze et al. CANCER CELL
- CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
- (2019) Ruilin Tian et al. NEURON
- Exploring genetic interaction manifolds constructed from rich single-cell phenotypes
- (2019) Thomas M. Norman et al. SCIENCE
- Optical Pooled Screens in Human Cells
- (2019) David Feldman et al. CELL
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
- (2019) Lai Wei et al. Nature Communications
- Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity
- (2019) Olli Dufva et al. BLOOD
- Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
- (2019) Kira S. Makarova et al. NATURE REVIEWS MICROBIOLOGY
- Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis
- (2018) Amir Giladi et al. NATURE CELL BIOLOGY
- On the design of CRISPR-based single-cell molecular screens
- (2018) Andrew J Hill et al. NATURE METHODS
- SAVER: gene expression recovery for single-cell RNA sequencing
- (2018) Mo Huang et al. NATURE METHODS
- Three-dimensional intact-tissue sequencing of single-cell transcriptional states
- (2018) Xiao Wang et al. SCIENCE
- Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
- (2018) Eric Shifrut et al. CELL
- Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
- (2018) Aleksandra Wroblewska et al. CELL
- Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks
- (2018) Adam J. Rubin et al. CELL
- Comparative Analysis of Droplet-Based Ultra-High-Throughput Single-Cell RNA-Seq Systems
- (2018) Xiannian Zhang et al. MOLECULAR CELL
- Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells
- (2018) Mridusmita Saikia et al. NATURE METHODS
- Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells
- (2017) Shiqi Xie et al. MOLECULAR CELL
- Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
- (2017) Kyuho Han et al. NATURE BIOTECHNOLOGY
- Multiplexed quantification of proteins and transcripts in single cells
- (2017) Vanessa M Peterson et al. NATURE BIOTECHNOLOGY
- Simultaneous epitope and transcriptome measurement in single cells
- (2017) Marlon Stoeckius et al. NATURE METHODS
- Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
- (2017) John Paul Shen et al. NATURE METHODS
- Pooled CRISPR screening with single-cell transcriptome readout
- (2017) Paul Datlinger et al. NATURE METHODS
- Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
- (2017) Julia Joung et al. Nature Protocols
- Am I ready for CRISPR? A user's guide to genetic screens
- (2017) John G. Doench NATURE REVIEWS GENETICS
- RNA editing with CRISPR-Cas13
- (2017) David B. T. Cox et al. SCIENCE
- Massively parallel digital transcriptional profiling of single cells
- (2017) Grace X. Y. Zheng et al. Nature Communications
- Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq
- (2016) Diego Adhemar Jaitin et al. CELL
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
- (2016) Atray Dixit et al. CELL
- A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
- (2016) Britt Adamson et al. CELL
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM
- (2016) Alan S. L. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions
- (2016) Victoria B. Stockman et al. PLoS One
- Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
- (2015) Allon M. Klein et al. CELL
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
- (2015) Bernd Zetsche et al. CELL
- Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
- (2015) Sergey Shmakov et al. MOLECULAR CELL
- Massively parallel high-order combinatorial genetics in human cells
- (2015) Alan S L Wong et al. NATURE BIOTECHNOLOGY
- Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues
- (2015) Je Hyuk Lee et al. Nature Protocols
- Spatially resolved, highly multiplexed RNA profiling in single cells
- (2015) K. H. Chen et al. SCIENCE
- Combinatorial labeling of single cells for gene expression cytometry
- (2015) H. C. Fan et al. SCIENCE
- Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells
- (2014) W Fiskus et al. LEUKEMIA
- Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex
- (2014) Alex A Pollen et al. NATURE BIOTECHNOLOGY
- Single-cell in situ RNA profiling by sequential hybridization
- (2014) Eric Lubeck et al. NATURE METHODS
- Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types
- (2014) D. A. Jaitin et al. SCIENCE
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
- (2012) Daniel Ramsköld et al. NATURE BIOTECHNOLOGY
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq
- (2011) S. Islam et al. GENOME RESEARCH
- Genomic Screening with RNAi: Results and Challenges
- (2010) Stephanie Mohr et al. Annual Review of Biochemistry
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