First-in-human therapy with Treg produced from thymic tissue (thyTreg) in a heart transplant infant

A Novel GMP Protocol to Produce High-Quality Treg Cells From the Pediatric Thymic Tissue to Be Employed as Cellular Therapy

(2022) Esther Bernaldo-de-Quirós et al.   Frontiers in Immunology

Untangling the Knots of Regulatory T Cell Therapy in Solid Organ Transplantation

(2022) Gabriel Orozco et al.   Frontiers in Immunology

A New Generation of Cell Therapies Employing Regulatory T Cells (Treg) to Induce Immune Tolerance in Pediatric Transplantation

(2022) Esther Bernaldo-de-Quirós et al.   Frontiers in Pediatrics

Basiliximab impairs regulatory T cell (TREG) function and could affect the short-term graft acceptance in children with heart transplantation

(2021) Jacobo López-Abente et al.   Scientific Reports

Adoptive Transfer of Regulatory Immune Cells in Organ Transplantation

(2021) Nathaniel Oberholtzer et al.   Frontiers in Immunology

Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure

(2020) Lola Jacquemont et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

(2020) Birgit Sawitzki et al.   LANCET

Infectious Tolerance as Seen With 2020 Vision: The Role of IL-35 and Extracellular Vesicles

(2020) Jeremy A. Sullivan et al.   Frontiers in Immunology

ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases

(2020) Dan-Yang Li et al.   Frontiers in Immunology

Methods to manufacture regulatory T cells for cell therapy

(2019) Katherine N. MacDonald et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Applicability, Safety And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation

(2019) Alberto Sánchez‐Fueyo et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CD45RA Distinguishes CD4+CD25+CD127−/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression

(2017) Rebeca Arroyo Hornero et al.   TRANSPLANTATION

A pilot study of operational tolerance with a regulatory T-cell-based cell therapy in living donor liver transplantation

(2016) Satoru Todo et al.   HEPATOLOGY

Discarded Human Thymus Is a Novel Source of Stable and Long-Lived Therapeutic Regulatory T Cells

(2015) I. E. Dijke et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

(2015) C. G. Brunstein et al.   BLOOD

Developing in vitro expanded CD45RA+regulatory T cells as an adoptive cell therapy for Crohn's disease

(2015) James B Canavan et al.   GUT

Markers of operational immune tolerance after pediatric liver transplantation in patients under immunosuppression

(2013) S. Schulz-Juergensen et al.   PEDIATRIC TRANSPLANTATION

Paediatric Reference Values for the Peripheral T cell Compartment

(2012) E. J. H. Schatorjé et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Suppression assays with human T regulatory cells: A technical guide

(2011) Alicia N. McMurchy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

(2011) Stephanie A. McClymont et al.   JOURNAL OF IMMUNOLOGY

Factors affecting operational tolerance after pediatric living-donor liver transplantation: impact of early post-transplant events and HLA match*

(2011) Hidenori Ohe et al.   TRANSPLANT INTERNATIONAL

Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation

(2009) Petra Hoffmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Indefinite mouse heart allograft survival in recipient treated with CD4+CD25+ regulatory T cells with indirect allospecificity and short term immunosuppression

(2009) Julia Yuen-Shan Tsang et al.   TRANSPLANT IMMUNOLOGY

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD