- Home
- Publications
- Publication Search
- Publication Details
Title
ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-08-28
DOI
10.3389/fimmu.2020.02104
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Type 2 Polarized T Cell Phenotype is Associated with Methotrexate Non‐response in Patients with Rheumatoid Arthritis
- (2020) Drew Slauenwhite et al. Arthritis & Rheumatology
- ICOS Is an Indicator of T-cell–Mediated Response to Cancer Immunotherapy
- (2020) Zunyu Xiao et al. CANCER RESEARCH
- Immune‐checkpoint molecules on regulatory T‐cells as a potential therapeutic target in head and neck squamous cell cancers
- (2020) Susumu Suzuki et al. CANCER SCIENCE
- Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
- (2020) Norihisa Mikami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cutting Edge: ICOS-Deficient Regulatory T Cells Display Normal Induction of Il10 but Readily Downregulate Expression of Foxp3
- (2019) Ashley E. Landuyt et al. JOURNAL OF IMMUNOLOGY
- IL-10 and ICOS Differentially Regulate T Cell Responses in the Brain during Chronic Toxoplasma gondii Infection
- (2019) Carleigh A. O’Brien et al. JOURNAL OF IMMUNOLOGY
- T follicular regulatory (Tfr) cells: Dissecting the complexity of Tfr‐cell compartments
- (2019) Válter R. Fonseca et al. IMMUNOLOGICAL REVIEWS
- CTLA-4–mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells
- (2019) Vitalijs Ovcinnikovs et al. Science Immunology
- Role of Inducible Co-Stimulator (ICOS) in cancer immunotherapy
- (2019) Florent Amatore et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- CD28 co-stimulation is dispensable for the steady state homeostasis of intestinal regulatory T cells
- (2018) Ei Wakamatsu et al. INTERNATIONAL IMMUNOLOGY
- ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells
- (2018) Qianmei Chen et al. International Journal of Medical Sciences
- Regulatory T cell subsets are differentially dependent on CD28 for their proliferation
- (2018) Ei Wakamatsu et al. MOLECULAR IMMUNOLOGY
- Revealing the specificity of regulatory T cells in murine autoimmune diabetes
- (2018) Allyson Spence et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brief Report: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multiple-Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis
- (2018) Laurence E. Cheng et al. Arthritis & Rheumatology
- CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production
- (2018) Lei Yu et al. Cell Death & Disease
- Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells
- (2018) Yixiang Han et al. Frontiers in Immunology
- JunB regulates homeostasis and suppressive functions of effector regulatory T cells
- (2018) Shin-ichi Koizumi et al. Nature Communications
- Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency
- (2017) Yannick Simoni et al. IMMUNITY
- The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells
- (2017) Lifan Xu et al. IMMUNITY
- An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function
- (2017) Hyunju Oh et al. IMMUNITY
- Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator–inducible T-cell costimulator ligand interaction
- (2017) Diamanda Rigas et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities
- (2017) Clélia Coutzac et al. Journal of Crohns & Colitis
- Identity and Diversity of Human Peripheral Th and T Regulatory Cells Defined by Single-Cell Mass Cytometry
- (2017) Matthew A. Kunicki et al. JOURNAL OF IMMUNOLOGY
- Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability
- (2017) Zhongmei Zhang et al. JOURNAL OF IMMUNOLOGY
- ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses
- (2017) Joseph C. Lownik et al. JOURNAL OF IMMUNOLOGY
- Regulatory T cells with superior immunosuppressive capacity emigrate from the inflamed colon to draining lymph nodes
- (2017) Y Nakanishi et al. Mucosal Immunology
- Stability and function of regulatory T cells expressing the transcription factor T-bet
- (2017) Andrew G. Levine et al. NATURE
- The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues
- (2017) Ajithkumar Vasanthakumar et al. Cell Reports
- Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
- (2016) Ana C. Anderson et al. IMMUNITY
- ICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated withHelicobacter pylori
- (2016) Hirotsugu Nagase et al. INTERNATIONAL JOURNAL OF CANCER
- Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?
- (2016) Anabelle Visperas et al. JOURNAL OF IMMUNOLOGY
- An essential role for the IL-2 receptor in Treg cell function
- (2016) Takatoshi Chinen et al. NATURE IMMUNOLOGY
- Novel Foxp3− IL-10− Regulatory T-cells Induced by B-Cells Alleviate Intestinal Inflammation in Vivo
- (2016) Tzu-Yu Shao et al. Scientific Reports
- ICOS Co-Stimulation: Friend or Foe?
- (2016) Daniel J. Wikenheiser et al. Frontiers in Immunology
- The clinical impact of ICOS signal in colorectal cancer patients
- (2016) Yan Zhang et al. OncoImmunology
- Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells - possible implications for the ICOS/ICOS-ligand axis in disease course and resolution
- (2015) P. Sakthivel et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity
- (2015) Hadi Maazi et al. IMMUNITY
- IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age
- (2015) Jana Raynor et al. JOURNAL OF IMMUNOLOGY
- Galectin-3 suppresses mucosal inflammation and reduces disease severity in experimental colitis
- (2015) Hwei-Fang Tsai et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
- (2015) B-H Yang et al. Mucosal Immunology
- Immune homeostasis enforced by co-localized effector and regulatory T cells
- (2015) Zhiduo Liu et al. NATURE
- Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses
- (2015) Sharad Shrestha et al. NATURE IMMUNOLOGY
- Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
- (2015) Alexandria Huynh et al. NATURE IMMUNOLOGY
- Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice
- (2015) Mara Kornete et al. PLoS One
- The microbiota regulates type 2 immunity through ROR t+ T cells
- (2015) C. Ohnmacht et al. SCIENCE
- Individual intestinal symbionts induce a distinct population of ROR + regulatory T cells
- (2015) E. Sefik et al. SCIENCE
- The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment
- (2015) M. D. Sharma et al. Science Advances
- Therapy of type 1 diabetes with CD4+CD25highCD127-regulatory T cells prolongs survival of pancreatic islets — Results of one year follow-up
- (2014) Natalia Marek-Trzonkowska et al. CLINICAL IMMUNOLOGY
- Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses
- (2014) Nicole Joller et al. IMMUNITY
- Down-Regulation of ICOS Ligand by Interaction with ICOS Functions as a Regulatory Mechanism for Immune Responses
- (2014) M. Watanabe et al. JOURNAL OF IMMUNOLOGY
- Expression of ICOS on Human Melanoma-Infiltrating CD4+CD25highFoxp3+ T Regulatory Cells: Implications and Impact on Tumor-Mediated Immune Suppression
- (2014) L. Strauss et al. JOURNAL OF IMMUNOLOGY
- ICOS Ligation Recruits the p50 PI3K Regulatory Subunit to the Immunological Synapse
- (2014) C. Fos et al. JOURNAL OF IMMUNOLOGY
- ICOS Controls the Pool Size of Effector-Memory and Regulatory T Cells
- (2014) Y. Burmeister et al. JOURNAL OF IMMUNOLOGY
- Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance
- (2014) Fang Yu et al. NATURE IMMUNOLOGY
- Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand
- (2014) D Nazzal et al. Cell Death & Disease
- ICOS controls Foxp3+regulatory T-cell expansion, maintenance and IL-10 production during helminth infection
- (2013) Stephen A. Redpath et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients
- (2013) Geok Choo Sim et al. JOURNAL OF CLINICAL INVESTIGATION
- TRAF3 regulates the effector function of regulatory T cells and humoral immune responses
- (2013) Jae-Hoon Chang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets
- (2013) Kate S. Smigiel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
- (2013) Koji Atarashi et al. NATURE
- mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
- (2013) Hu Zeng et al. NATURE
- Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
- (2013) Wim Pierson et al. NATURE IMMUNOLOGY
- ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner
- (2013) Jian Zheng et al. PLoS One
- CD4 T Cells Require ICOS-Mediated PI3K Signaling to Increase T-Bet Expression in the Setting of Anti-CTLA-4 Therapy
- (2013) H. Chen et al. Cancer Immunology Research
- Increased Frequency of ICOS+ CD4 T Cells as a Pharmacodynamic Biomarker for Anti-CTLA-4 Therapy
- (2013) D. Ng Tang et al. Cancer Immunology Research
- Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells
- (2012) T. Duhen et al. BLOOD
- ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells
- (2012) J. Faget et al. CANCER RESEARCH
- Administration of CD4+CD25highCD127- Regulatory T Cells Preserves -Cell Function in Type 1 Diabetes in Children
- (2012) N. Marek-Trzonkowska et al. DIABETES CARE
- Acceleration of diabetes development in CXC chemokine receptor 3 (CXCR3)-deficient NOD mice
- (2012) Y. Yamada et al. DIABETOLOGIA
- Murine Regulatory T Cells Contain Hyperproliferative and Death-Prone Subsets with Differential ICOS Expression
- (2012) Y. Chen et al. JOURNAL OF IMMUNOLOGY
- ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma
- (2012) K. H. Shalaby et al. JOURNAL OF IMMUNOLOGY
- ICOS-Dependent Homeostasis and Function of Foxp3+ Regulatory T Cells in Islets of Nonobese Diabetic Mice
- (2012) M. Kornete et al. JOURNAL OF IMMUNOLOGY
- ICOS Mediates the Generation and Function of CD4+CD25+Foxp3+ Regulatory T Cells Conveying Respiratory Tolerance
- (2012) M. Busse et al. JOURNAL OF IMMUNOLOGY
- Inducible Costimulator Controls Migration of T Cells to the Lungs via Down-Regulation of CCR7 and CD62L
- (2011) Tamson V. Moore et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- IL-2 production by dendritic cells promotes Foxp3+regulatory T-cell expansion in autoimmune-resistant NOD congenic mice
- (2011) Evridiki Sgouroudis et al. AUTOIMMUNITY
- Interleukin-12 Converts Foxp3+ Regulatory T Cells to Interferon–γ-Producing Foxp3+ T Cells That Inhibit Colitis
- (2011) Ting Feng et al. GASTROENTEROLOGY
- IL-35 production by inducible costimulator (ICOS)–positive regulatory T cells reverses established IL-17–dependent allergic airways disease
- (2011) Gregory S. Whitehead et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Foxp3+ Regulatory T Cells of Psoriasis Patients Easily Differentiate into IL-17A-Producing Cells and Are Found in Lesional Skin
- (2011) H. Jorn Bovenschen et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Elevated circulating CD4+ICOS+Foxp3+ T cells contribute to overproduction of IL-10 and are correlated with disease severity in patients with systemic lupus erythematosus
- (2011) Y Liu et al. LUPUS
- The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
- (2011) Erika Cretney et al. NATURE IMMUNOLOGY
- Preoperative CTLA-4 Blockade: Tolerability and Immune Monitoring in the Setting of a Presurgical Clinical Trial
- (2010) B. C. Carthon et al. CLINICAL CANCER RESEARCH
- Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells
- (2010) Marc Vocanson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
- (2010) Yenkel Grinberg-Bleyer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Major Role for Bim in Regulatory T Cell Homeostasis
- (2010) C. A. Chougnet et al. JOURNAL OF IMMUNOLOGY
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
- (2010) K. Atarashi et al. SCIENCE
- Flt3-L Increases CD4+CD25+Foxp3+ICOS+Cells in the Lungs of Cockroach-Sensitized and -Challenged Mice
- (2009) Halvor S. McGee et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Anti-CTLA-4 treatment induces IL-10-producing ICOS+ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitis
- (2009) C Coquerelle et al. GUT
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
- (2009) Greg M. Delgoffe et al. IMMUNITY
- Fms-like tyrosine kinase 3 ligand increases a lung DC subset with regulatory properties in allergic airway inflammation
- (2009) Zhifei Shao et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The Role of ICOS in Directing T Cell Responses: ICOS-Dependent Induction of T Cell Anergy by Tolerogenic Dendritic Cells
- (2009) A. Tuettenberg et al. JOURNAL OF IMMUNOLOGY
- Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
- (2009) Ye Zheng et al. NATURE
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
- (2009) Xuyu Zhou et al. NATURE IMMUNOLOGY
- The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
- (2009) Meghan A Koch et al. NATURE IMMUNOLOGY
- Anti-CTLA-4 therapy results in higher CD4+ICOShiT cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues
- (2009) Hong Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery
- (2008) Tomoki Ito et al. IMMUNITY
- Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
- (2008) Yuri P. Rubtsov et al. IMMUNITY
- Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction
- (2008) Qizhi Tang et al. IMMUNITY
- CTLA-4 blockade increases IFN -producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
- (2008) C. I. Liakou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CTLA-4 Control over Foxp3+ Regulatory T Cell Function
- (2008) K. Wing et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started