Histone acetylation regulates ORMDL3 expression‐mediated NLRP3 inflammasome overexpression during RSV‐allergic exacerbation mice

Increased expression of ORMDL3 in allergic asthma: a case control and in vitro study

(2022) Joanna Nowakowska et al.   JOURNAL OF ASTHMA

European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years

(2021) Erol A. Gaillard et al.   EUROPEAN RESPIRATORY JOURNAL

Investigating the regulatory role of ORMDL3 in airway barrier dysfunction using in vivo and in vitro models

(2019) Ruixue Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Ormdl3 and Allergic Asthma: from Physiology to Pathology

(2019) Briana James et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ORMDL3 knockdown in the lungs alleviates airway inflammation and airway remodeling in asthmatic mice via JNK1/2-MMP-9 pathway

(2019) Huan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prevalence, risk factors, and management of asthma in China: a national cross-sectional study

(2019) Kewu Huang et al.   LANCET

p300 mediates the histone acetylation of ORMDL3 to affect airway inflammation and remodeling in asthma

(2019) Qi Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting NLRP3 Inflammasome Activation in Severe Asthma

(2019) Efthymia Theofani et al.   Journal of Clinical Medicine

Mechanisms and roles by which IRF-3 mediates the regulation of ORMDL3 transcription in respiratory syncytial virus infection

(2017) Xiao-Hua Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α–Endoplasmic Reticulum Stress–Beclin1 Autophagy Regulatory Pathway

(2017) Jie Dang et al.   JOURNAL OF IMMUNOLOGY

ORMDL3 may participate in the pathogenesis of bronchial epithelial‑mesenchymal transition in asthmatic mice with airway remodeling

(2017) Qi Cheng et al.   Molecular Medicine Reports

Sphingolipids, ORMDL3 and asthma

(2016) Tilla S. Worgall   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Gu-Ben-Fang-Xiao decoction attenuates sustained airway inflammation by suppressing ER stress response in a murine asthma remission model of respiratory syncytial virus infection

(2016) Yuan Lu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

(2015) Denise N. Bronner et al.   IMMUNITY

Viral infections and asthma: an inflammatory interface?

(2014) Brian G.G. Oliver et al.   EUROPEAN RESPIRATORY JOURNAL

Assessing the association of early life antibiotic prescription with asthma exacerbations, impaired antiviral immunity, and genetic variants in 17q21: a population-based birth cohort study

(2014) Aida Semic-Jusufagic et al.   Lancet Respiratory Medicine

Rhinovirus-Induced Calcium Flux Triggers NLRP3 and NLRC5 Activation in Bronchial Cells

(2013) Kathy Triantafilou et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways

(2013) Sena Kim et al.   Innate Immunity

Rhinovirus Wheezing Illness and Genetic Risk of Childhood-Onset Asthma

(2013) Minal Çalışkan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Promoter Characterization and Role of cAMP/PKA/CREB in the Basal Transcription of the Mouse ORMDL3 Gene

(2013) Li-Li Zhuang et al.   PLoS One

Cellular and humoral immunity of virus-induced asthma

(2013) Yoshimichi Okayama   Frontiers in Microbiology

Mechanisms elevating ORMDL3 expression in recurrent wheeze patients: Role of Ets-1, p300 and CREB

(2012) Rui Jin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6

(2012) M. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association study to identify genetic determinants of severe asthma

(2012) Y I Wan et al.   THORAX

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

(2011) M. Vareille et al.   CLINICAL MICROBIOLOGY REVIEWS

Asthma genetics and genomics 2009

(2009) Scott T Weiss et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

17q21 variants modify the association between early respiratory infections and asthma

(2009) L. A. M. Smit et al.   EUROPEAN RESPIRATORY JOURNAL

The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress

(2009) Gerard Cantero-Recasens et al.   HUMAN MOLECULAR GENETICS

Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population

(2007) Tomomitsu Hirota et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY