ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α–Endoplasmic Reticulum Stress–Beclin1 Autophagy Regulatory Pathway

The role of ORMDL proteins, guardians of cellular sphingolipids, in asthma

(2016) T. Paulenda et al.   ALLERGY

Quinocetone triggered ER stress-induced autophagy via ATF6/DAPK1-modulated mAtg9a trafficking

(2016) Yan Zhou et al.   CELL BIOLOGY AND TOXICOLOGY

Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses

(2015) J Arnold et al.   CELL DEATH AND DIFFERENTIATION

Correlation between the genetic polymorphism of ORMDL3 gene and asthma risk: a meta-analysis

(2015) W.H. Zhai et al.   GENETICS AND MOLECULAR RESEARCH

Autophagy in autoimmune disease

(2015) Zhen Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

ORMDL3 contributes to the risk of atherosclerosis in Chinese Han population and mediates oxidized low-density lipoprotein-induced autophagy in endothelial cells

(2015) Xiaochun Ma et al.   Scientific Reports

The autophagy geneATG5plays an essential role in B lymphocyte development

(2014) Brian C. Miller et al.   Autophagy

Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression

(2014) Ji Wang et al.   Autophagy

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells

(2014) XIU CHENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Coordinated Regulation of the Orosomucoid-like Gene Family Expression Controlsde NovoCeramide Synthesis in Mammalian Cells

(2014) Kerstin Kiefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma

(2014) M. Miller et al.   JOURNAL OF IMMUNOLOGY

Genetic variants of 17q21 are associated with childhood-onset asthma and related phenotypes in a northeastern Han Chinese population: a case-control study

(2014) X. Yu et al.   TISSUE ANTIGENS

Recent insights on the putative role of autophagy in autoimmune diseases

(2013) Elena Gianchecchi et al.   AUTOIMMUNITY REVIEWS

ATG5 regulates plasma cell differentiation

(2013) Kara L. Conway et al.   Autophagy

PERK-ing up autophagy during MYC-induced tumorigenesis

(2013) Souvik Dey et al.   Autophagy

B cell activating factor (BAFF) induces the transcription of recombination-activating genes in transitional stage 1 B cells

(2013) Youdi He et al.   Central European Journal of Immunology

Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression

(2013) Rongfang Qiu et al.   FEBS Journal

Replication and fine mapping of asthma-associated loci in individuals of African ancestry

(2013) David B. Kantor et al.   HUMAN GENETICS

Plasma cells require autophagy for sustainable immunoglobulin production

(2013) Niccolò Pengo et al.   NATURE IMMUNOLOGY

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

(2013) Wafa B’chir et al.   NUCLEIC ACIDS RESEARCH

Genetic variants on 17q21 are associated with ankylosing spondylitis susceptibility and severity in a Chinese Han population

(2013) R Qiu et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48

(2013) Sung Gil Ha et al.   Nature Communications

Macroautophagy is deregulated in murine and human lupus T lymphocytes

(2012) Frédéric Gros et al.   Autophagy

Targeted deletion of Atg5 reveals differential roles of autophagy in keratin K5-expressing epithelia

(2012) Supawadee Sukseree et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ORMDL3 modulates store-operated calcium entry and lymphocyte activation

(2012) Amado Carreras-Sureda et al.   HUMAN MOLECULAR GENETICS

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6

(2012) M. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macroautophagy in T Lymphocyte Development and Function

(2012) Ming-Xiao He et al.   Frontiers in Immunology

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes

(2011) Nada M. Saleh et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Temporal Regulation of Intracellular Organelle Homeostasis in T Lymphocytes by Autophagy

(2011) W. Jia et al.   JOURNAL OF IMMUNOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis

(2010) Craig M. Walsh et al.   IMMUNOLOGICAL REVIEWS

Orm family proteins mediate sphingolipid homeostasis

(2010) David K. Breslow et al.   NATURE

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2α in caspase-3/7-deficient cells

(2010) K W Kim et al.   ONCOGENE

Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis

(2010) Debby Laukens et al.   PLoS One

The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress

(2009) Gerard Cantero-Recasens et al.   HUMAN MOLECULAR GENETICS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Vitamin D3 Induces Autophagy of Human Myeloid Leukemia Cells

(2008) Jianrong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY