The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

Airway Epithelial Cells Regulate the Functional Phenotype of Locally Differentiating Dendritic Cells: Implications for the Pathogenesis of Infectious and Allergic Airway Disease

(2014) A. Rate et al.   JOURNAL OF IMMUNOLOGY

Monocyte Differentiation toward Regulatory Dendritic Cells Is Not Affected by Respiratory Syncytial Virus–Induced Inflammatory Mediators

(2010) Koenraad F. van der Sluijs et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection

(2010) Kelvin K. W. To et al.   CLINICAL INFECTIOUS DISEASES

Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology

(2010) J. S. Tregoning et al.   CLINICAL MICROBIOLOGY REVIEWS

Combined airways: impact of upper airway on lower airway

(2010) Mary Beth Fasano   Current Opinion in Otolaryngology & Head and Neck Surgery

Azithromycin induces anti-viral responses in bronchial epithelial cells

(2010) V. Gielen et al.   EUROPEAN RESPIRATORY JOURNAL

Pseudomonas aeruginosabiofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies

(2010) Daniel J Hassett et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Imaging of lung inflammation during severe influenza A: H1N1

(2010) Giacomo Bellani et al.   INTENSIVE CARE MEDICINE

Molecular characterization and distinguishing features of a novel human rhinovirus (HRV) C, HRVC-QCE, detected in children with fever, cough and wheeze during 2003

(2010) K.E. Arden et al.   JOURNAL OF CLINICAL VIROLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Local Production of Inflammatory Mediators During Childhood Parainfluenza Virus Infection

(2010) Rana E. El Feghaly et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

(2010) T. Satoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the Noninflammasome NLRs Function in the Innate Immune System

(2010) J. P. Y. Ting et al.   SCIENCE

RIGorous Detection: Exposing Virus Through RNA Sensing

(2010) J. Rehwinkel et al.   SCIENCE

Influenza Virus Infection Decreases Tracheal Mucociliary Velocity and Clearance ofStreptococcus pneumoniae

(2009) Lynnelle A. Pittet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Type III IFNs: New layers of complexity in innate antiviral immunity

(2009) Nina Ank et al.   BIOFACTORS

Intercellular Junctional Proteins as Receptors and Barriers to Virus Infection and Spread

(2009) Jeffrey M. Bergelson   Cell Host & Microbe

Mucins, Mucus, and Sputum

(2009) Judith A. Voynow et al.   CHEST

Budesonide and formoterol inhibit inflammatory mediator production by bronchial epithelial cells infected with rhinovirus

(2009) C. L. Skevaki et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Impact of bacterial colonization on the severity and airway inflammation of children with virus induced wheezing

(2009) Deng Yu et al.   CLINICAL MICROBIOLOGY AND INFECTION

Influenza A virus-induced caspase-3 cleaves the histone deacetylase 6 in infected epithelial cells

(2009) Matloob Husain et al.   FEBS LETTERS

The host response and molecular pathogenesis associated with respiratory syncytial virus infection

(2009) Christine M Oshansky et al.   Future Microbiology

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-κB pathways in rhinovirus-infected epithelial cells

(2009) Rommy Koetzler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects

(2009) Nilceia Lopez-Souza et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Retinoic Acid-induced Gene-1 (RIG-I) Associates with the Actin Cytoskeleton via Caspase Activation and Recruitment Domain-dependent Interactions

(2009) Amitava Mukherjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prevalence and Clinical Characterization of a Newly Identified Human Rhinovirus C Species in Children with Acute Respiratory Tract Infections

(2009) Y. Jin et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations

(2009) Gaston De Serres et al.   JOURNAL OF CLINICAL VIROLOGY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interactions of  -,  -, and  -Defensins with Influenza A Virus and Surfactant Protein D

(2009) M. Doss et al.   JOURNAL OF IMMUNOLOGY

CXCR2 Is Required for Neutrophilic Airway Inflammation and Hyperresponsiveness in a Mouse Model of Human Rhinovirus Infection

(2009) D. R. Nagarkar et al.   JOURNAL OF IMMUNOLOGY

Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses

(2009) Q. Wang et al.   JOURNAL OF IMMUNOLOGY

Cytokine Profiles Induced by the Novel Swine‐Origin Influenza A/H1N1 Virus: Implications for Treatment Strategies

(2009) Patrick C. Y. Woo et al.   JOURNAL OF INFECTIOUS DISEASES

Viral Evasion of the Interferon System

(2009) Michael Gale et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-λs: the modulators of antivirus, antitumor, and immune responses

(2009) Mingcai Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

(2009) Z. Ling et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus-Induced Activation and Migration of Respiratory Dendritic Cells and Subsequent Antigen Presentation in the Lung-Draining Lymph Node

(2009) M. V. Lukens et al.   JOURNAL OF VIROLOGY

Pandemic H1N1 2009 Influenza A Virus Induces Weak Cytokine Responses in Human Macrophages and Dendritic Cells and Is Highly Sensitive to the Antiviral Actions of Interferons

(2009) P. Osterlund et al.   JOURNAL OF VIROLOGY

Rhinovirus upregulates matrix metalloproteinase-2, matrix metalloproteinase-9, and vascular endothelial growth factor expression in nasal polyp fibroblasts

(2009) Jong Hwan Wang et al.   LARYNGOSCOPE

Rhinovirus enhances various bacterial adhesions to nasal epithelial cells simultaneously

(2009) Jong Hwan Wang et al.   LARYNGOSCOPE

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma

(2009) Y A Bochkov et al.   Mucosal Immunology

Novel Influenza A(H1N1)

(2009) Rini Jain et al.   PEDIATRIC EMERGENCY CARE

The Effects of Disodium Cromoglycate on Enhanced Adherence of Haemophilus influenzae to A549 Cells Infected With Respiratory Syncytial Virus

(2009) Chie Fukasawa et al.   PEDIATRIC RESEARCH

Pathogen recognition by innate immunity and its signaling

(2009) Shizuo AKIRA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Innate immune responses to influenza A H5N1: friend or foe?

(2009) Joseph Sriyal Malik Peiris et al.   TRENDS IN IMMUNOLOGY

Study of Montelukast for the Treatment of Respiratory Symptoms of Post–Respiratory Syncytial Virus Bronchiolitis in Children

(2008) Hans Bisgaard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gene Expression Profiles duringIn VivoHuman Rhinovirus Infection

(2008) David Proud et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rhinovirus Disrupts the Barrier Function of Polarized Airway Epithelial Cells

(2008) Umadevi Sajjan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human Metapneumovirus Inhibits IFN-α Signaling through Inhibition of STAT1 Phosphorylation

(2008) Darrell L. Dinwiddie et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Rhinovirus-Induced Major Airway Mucin Production Involves a Novel TLR3-EGFR–Dependent Pathway

(2008) Lingxiang Zhu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Immunity to Respiratory Viruses

(2008) Jacob E. Kohlmeier et al.   Annual Review of Immunology

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Viral Infection in Adults Hospitalized With Community-Acquired Pneumonia

(2008) Jennie Johnstone et al.   CHEST

Modulation of the epithelial inflammatory response to rhinovirus in an atopic environment

(2008) M. Xatzipsalti et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Severe Pneumonia Due to Adenovirus Serotype 14: A New Respiratory Threat?

(2008) J. K. Louie et al.   CLINICAL INFECTIOUS DISEASES

Human Bocavirus: Passenger or Pathogen in Acute Respiratory Tract Infections?

(2008) O. Schildgen et al.   CLINICAL MICROBIOLOGY REVIEWS

Toll-like receptors in the respiratory system: Their roles in inflammation

(2008) Chiaki Iwamura et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Rhinovirus and the initiation of asthma

(2008) James E Gern   Current Opinion in Allergy and Clinical Immunology

Human bocavirus: clinical significance and implications

(2008) Jeffrey Kahn   CURRENT OPINION IN PEDIATRICS

Role of Cilia, Mucus, and Airway Surface Liquid in Mucociliary Dysfunction: Lessons from Mouse Models

(2008) Marcus A. Mall   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Etiology of asthma exacerbations

(2008) Annemarie Sykes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling

(2008) Richard Leigh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of Human β-Defensin-2 during Tumor Necrosis Factor-α/NF-κB-mediated Innate Antiviral Response against Human Respiratory Syncytial Virus

(2008) Srikanth Kota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Select Paramyxoviral V Proteins Inhibit IRF3 Activation by Acting as Alternative Substrates for Inhibitor of κB Kinase ϵ (IKKe)/TBK1

(2008) Lenette L. Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging respiratory agents: New viruses for old diseases?

(2008) T.P. Sloots et al.   JOURNAL OF CLINICAL VIROLOGY

Human rhinoviruses: The cold wars resume

(2008) Ian M. Mackay   JOURNAL OF CLINICAL VIROLOGY

The role of respiratory viruses in cystic fibrosis

(2008) Dennis Wat et al.   Journal of Cystic Fibrosis

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Respiratory Pathogens in Children with and without Respiratory Symptoms

(2008) Marieke M. van der Zalm et al.   JOURNAL OF PEDIATRICS

Respiratory Syncytial Virus Activates Innate Immunity through Toll-Like Receptor 2

(2008) M. R. Murawski et al.   JOURNAL OF VIROLOGY

Severe Acute Respiratory Syndrome (SARS) Coronavirus-Induced Lung Epithelial Cytokines Exacerbate SARS Pathogenesis by Modulating Intrinsic Functions of Monocyte-Derived Macrophages and Dendritic Cells

(2008) T. Yoshikawa et al.   JOURNAL OF VIROLOGY

Human infection with highly pathogenic H5N1 influenza virus

(2008) Andrea Gambotto et al.   LANCET

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

(2008) Daniel A. Muruve et al.   NATURE

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

(2008) Nathan W Bartlett et al.   NATURE MEDICINE

Innate immune response to viral infection of the lungs

(2008) Hayley See et al.   Paediatric Respiratory Reviews

The Balance between Plasmacytoid DC versus Conventional DC Determines Pulmonary Immunity to Virus Infections

(2008) Joost J. Smit et al.   PLoS One

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

(2008) S. D. Message et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Healthy but not RSV-infected lung epithelial cells profoundly inhibit T cell activation

(2008) H Wang et al.   THORAX

Pathology of human influenza revisited

(2008) Thijs Kuiken et al.   VACCINE

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens

Structure and Function of the Polymeric Mucins in Airways Mucus

(2007) David J. Thornton et al.   Annual Review of Physiology

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY

The platelet activating factor receptor is not required for exacerbation of bacterial pneumonia following influenza

(2007) Jonathan A. Mccullers et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES