Strategies for acquisition of resonance assignment spectra of highly dynamic membrane proteins: a GPCR case study

Cholesterol Biases the Conformational Landscape of the Chemokine Receptor CCR3: A MAS SSNMR-Filtered Molecular Dynamics Study

(2023) Evan J. van Aalst et al.   Journal of Chemical Information and Modeling

Dual mechanisms of cholesterol-GPCR interactions that depend on membrane phospholipid composition

(2023) Arka Prabha Ray et al.   STRUCTURE

Spectroscopic signatures of bilayer ordering in native biological membranes

(2022) Evan J. van Aalst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

High-Resolution Magic Angle Spinning NMR of KcsA in Liposomes: The Highly Mobile C-Terminus

(2022) Gary S. Howarth et al.   Biomolecules

NMR-Based Methods for Protein Analysis

(2021) Yunfei Hu et al.   ANALYTICAL CHEMISTRY

Cross-seeding Between the Functional Amyloidogenic CRES and CRES3 Family Members and their Regulation of Aβ Assembly

(2021) Hoa Quynh Do et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Water orientation and dynamics in the closed and open influenza B virus M2 proton channels

(2021) Martin D. Gelenter et al.   Communications Biology

Rapid 2H NMR Transverse Relaxation of Perdeuterated Lipid Acyl Chains of Membrane with Bound Viral Fusion Peptide Supports Large-Amplitude Motions of These Chains That Can Catalyze Membrane Fusion

(2021) Ujjayini Ghosh et al.   BIOCHEMISTRY

Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-β Fibrils

(2021) Ayesha Wickramasinghe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling

(2021) Evan van Aalst et al.   Frontiers in Molecular Biosciences

In Silico Identification of Cholesterol Binding Motifs in the Chemokine Receptor CCR3

(2021) Evan van Aalst et al.   Membranes

Light Dynamics of the Retinal‐Disease‐Relevant G90D Bovine Rhodopsin Mutant

(2020) Nina Kubatova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer Membranes

(2020) Ulrike Krug et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Lipid Activation Mechanism of a Transmembrane Potassium Channel

(2020) Collin G. Borcik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation

(2020) Alexander Vogel et al.   MOLECULES

Shifts in the selectivity filter dynamics cause modal gating in K+ channels

(2019) Shehrazade Jekhmane et al.   Nature Communications

An Inward-Rectifier Potassium Channel Coordinates the Properties of Biologically Derived Membranes

(2019) Collin G. Borcik et al.   BIOPHYSICAL JOURNAL

The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors

(2018) Lisa Joedicke et al.   Nature Chemical Biology

Assessment of the sensitivity of DQF/ZQF 2 H NMR of D 2 O for studying modified nafion membranes at 20 °C and 80 °C

(2018) Alyxandra N. Thiessen et al.   SOLID STATE NUCLEAR MAGNETIC RESONANCE

Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data

(2016) Jinfa Ying et al.   JOURNAL OF BIOMOLECULAR NMR

Free backbone carbonyls mediate rhodopsin activation

(2016) Naoki Kimata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Studying dynamics by magic-angle spinning solid-state NMR spectroscopy: Principles and applications to biomolecules

(2016) Paul Schanda et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

(2016) Naoki Kimata et al.   Nature Communications

Free backbone carbonyls mediate rhodopsin activation

(2016) Naoki Kimata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Correlating lipid bilayer fluidity with sensitivity and resolution of polytopic membrane protein spectra by solid-state NMR spectroscopy

(2015) James R. Banigan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

Solid-State NMR Approaches to Internal Dynamics of Proteins: From Picoseconds to Microseconds and Seconds

(2013) Alexey Krushelnitsky et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Efficient resonance assignment of proteins in MAS NMR by simultaneous intra- and inter-residue 3D correlation spectroscopy

(2013) Eugenio Daviso et al.   JOURNAL OF BIOMOLECULAR NMR

Nmrglue: an open source Python package for the analysis of multidimensional NMR data

(2013) Jonathan J. Helmus et al.   JOURNAL OF BIOMOLECULAR NMR

Signal intensities in 1H–13C CP and INEPT MAS NMR of liquid crystals

(2013) A. Nowacka et al.   JOURNAL OF MAGNETIC RESONANCE

Quantifying conformational dynamics using solid-state R1ρ experiments

(2012) Caitlin M. Quinn et al.   JOURNAL OF MAGNETIC RESONANCE

Structure of the chemokine receptor CXCR1 in phospholipid bilayers

(2012) Sang Ho Park et al.   NATURE

Molecular simulations and solid-state NMR investigate dynamical structure in rhodopsin activation

(2011) Blake Mertz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation

(2011) Andrey V Struts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsin

(2011) A. V. Struts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assignment Strategies for Large Proteins by Magic-Angle Spinning NMR: The 21-kDa Disulfide-Bond-Forming Enzyme DsbA

(2010) Lindsay J. Sperling et al.   JOURNAL OF MOLECULAR BIOLOGY

Polarization Transfer Solid-State NMR for Studying Surfactant Phase Behavior

(2010) Agnieszka Nowacka et al.   LANGMUIR

A general protocol for temperature calibration of MAS NMR probes at arbitrary spinning speeds

(2010) Xudong Guan et al.   SOLID STATE NUCLEAR MAGNETIC RESONANCE

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation

(2009) Shivani Ahuja et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY