Benzylic C–H trifluoromethylation of phenol derivatives

Benzylic C(sp3)H Perfluoroalkylation of Six-Membered Heteroaromatic Compounds

(2015) Yoichiro Kuninobu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-Mediated Oxidative Trifluoromethylation of Phenols: Direct Synthesis of Aryl Trifluoromethyl Ethers

(2015) Jian-Bo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Trifluoromethylation and Trifluoromethylthiolation Reactions Using (Trifluoromethyl)trimethylsilane as a Nucleophilic CF3 Source

(2014) Lingling Chu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

(2014) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cascade CH Trifluoroethylation of Aryl Iodides and Heck Reaction: Efficient Synthesis ofortho-Trifluoroethylstyrenes

(2014) Hao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Addition of CF3 across unsaturated moieties: a powerful functionalization tool

(2014) Estíbaliz Merino et al.   CHEMICAL SOCIETY REVIEWS

Dual Catalysis with Copper and Rhenium for Trifluoromethylation of Propargylic Alcohols: Efficient Synthesis of α-Trifluoromethylated Enones

(2014) Hiromichi Egami et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent progress in transition-metal-catalyzed trifluoromethylation of olefins using electrophilic CF3 reagents

(2014) Takashi Koike et al.   JOURNAL OF FLUORINE CHEMISTRY

Metal-Free Trifluoromethylation of Aromatic and Heteroaromatic Aldehydes and Ketones

(2014) Yupu Qiao et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-catalyzed nucleophilic trifluoromethylation of benzylic chlorides

(2014) Yoshihiro Miyake et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Visible-Light-Promoted Radical C–H Trifluoromethylation of Free Anilines

(2014) Jin Xie et al.   ORGANIC LETTERS

Copper-Promoted Reductive Coupling of Aryl Iodides with 1,1,1-Trifluoro-2-iodoethane

(2014) Song Xu et al.   ORGANIC LETTERS

Catalytic C–H α-Trifluoromethylation of α,β-Unsaturated Carbonyl Compounds

(2014) Zhongxue Fang et al.   ORGANIC LETTERS

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-mediated C–H trifluoromethylation of quinones

(2013) Nadia O. Ilchenko et al.   CHEMICAL COMMUNICATIONS

CuCl-catalyzed ortho trifluoromethylation of arenes and heteroarenes with a pivalamido directing group

(2013) Shangjun Cai et al.   CHEMICAL COMMUNICATIONS

Facile synthesis of trifluoroethyl compounds by the Suzuki cross-coupling reactions of CF3CH2OTs with arylboronic acids

(2013) Faqiang Leng et al.   CHEMICAL COMMUNICATIONS

Copper-Mediated Deoxygenative Trifluoromethylation of Benzylic Xanthates: Generation of a CCF3Bond from an O-Based Electrophile

(2013) Lingui Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Synthesis of Hypervalent Iodine Reagents for Electrophilic Trifluoromethylation

(2013) Václav Matoušek et al.   JOURNAL OF ORGANIC CHEMISTRY

Notification about the Explosive Properties of Togni’s Reagent II and One of Its Precursors

(2013) Nikolaus Fiederling et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Copper-Catalyzed Trifluoromethylation of Allylsilanes

(2012) Ryo Shimizu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters

(2012) Apeng Liang et al.   CHEMICAL COMMUNICATIONS

Selective trifluoromethylation and alkynylation of tetrahydroisoquinolines using visible light irradiation by Rose Bengal

(2012) Weijun Fu et al.   JOURNAL OF FLUORINE CHEMISTRY

From Triclosan toward the Clinic: Discovery of Nonbiocidal, Potent FabI Inhibitors for the Treatment of Resistant Bacteria

(2012) Vincent Gerusz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pd(II)-Catalyzed Ortho Trifluoromethylation of Arenes and Insights into the Coordination Mode of Acidic Amide Directing Groups

(2012) Xing-Guo Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Trifluoromethylation of Aromatic C–H Bond Directed by an Acetamino Group

(2012) Li-Sheng Zhang et al.   ORGANIC LETTERS

Rhenium-Catalyzed Trifluoromethylation of Arenes and Heteroarenes by Hypervalent Iodine Reagents

(2012) Esteban Mejía et al.   ACS Catalysis

Palladium-Catalyzed 2,2,2-Trifluoroethylation of Organoboronic Acids and Esters

(2011) Yanchuan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A simple, rapid procedure for nucleophilic radiosynthesis of aliphatic [18F]trifluoromethyl groups

(2011) Patrick J. Riss et al.   CHEMICAL COMMUNICATIONS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Oxidative Trifluoromethylation of Indoles at Room Temperature

(2011) Xin Mu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Me3SiCF3/AgF/Cu—A new reagents combination for selective trifluoromethylation of various organic halides by trifluoromethylcopper, CuCF3

(2011) Mikhail M. Kremlev et al.   JOURNAL OF FLUORINE CHEMISTRY

Copper-Catalyzed Direct C–H Oxidative Trifluoromethylation of Heteroarenes

(2011) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Cu-Mediated Chemoselective Trifluoromethylation of Benzyl Bromides Using Shelf-Stable Electrophilic Trifluoromethylating Reagents

(2011) Hiroyuki Kawai et al.   ORGANIC LETTERS

Silver-Mediated Trifluoromethylation of Arenes Using TMSCF3

(2011) Yingda Ye et al.   ORGANIC LETTERS

Innate C-H trifluoromethylation of heterocycles

(2011) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper-catalyzed oxidative trifluoromethylation of benzylic sp3 C–H bond adjacent to nitrogen in amines

(2011) Hiromasa Mitsudera et al.   TETRAHEDRON LETTERS

Benzoyl peroxide (BPO)-promoted oxidative trifluoromethylation of tertiary amines with trimethyl(trifluoromethyl)silane

(2010) Lingling Chu et al.   CHEMICAL COMMUNICATIONS

Fluorine in health care: Organofluorine containing blockbuster drugs

(2010) David O’Hagan   JOURNAL OF FLUORINE CHEMISTRY

Pd(II)-Catalyzedortho-Trifluoromethylation of Arenes Using TFA as a Promoter

(2010) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidation of a Cyclometalated Pd(II) Dimer with “CF3+”: Formation and Reactivity of a Catalytically Competent Monomeric Pd(IV) Aquo Complex

(2010) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C2-trifluoromethylation of indole derivatives catalyzed by copper acetate

(2010) Ryo Shimizu et al.   TETRAHEDRON LETTERS

Trifluoromethylation of various aromatic compounds by CF3I in the presence of Fe(II) compound, H2O2 and dimethylsulfoxide

(2009) Tatsuhito Kino et al.   JOURNAL OF FLUORINE CHEMISTRY

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Reactivity of a 10-I-3 Hypervalent Iodine Trifluoromethylation Reagent With Phenols

(2008) Kyrill Stanek et al.   JOURNAL OF ORGANIC CHEMISTRY

Active Trifluoromethylating Agents from Well-Defined Copper(I)−CF3Complexes

(2008) Galyna G. Dubinina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS