Ginsenoside Rg5 alleviates Ang II–induced cardiac inflammation and remodeling by inhibiting the JNK/AP-1 pathway

A systematic exploration of ginsenoside Rg5 reveals anti-inflammatory functions in airway mucosa cells

(2022) Hyojin Heo et al.   Journal of Ginseng Research

Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice

(2021) Yanyan Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmacological activities of ginsenoside Rg5 (Review)

(2021) Ming-Yang Liu et al.   Experimental and Therapeutic Medicine

Crosstalk between the renin-angiotensin system and the endoplasmic reticulum stress in the cardiovascular system: Lessons learned so far

(2021) Vinicius Sepúlveda-Fragoso et al.   LIFE SCIENCES

The Role of the Inflammasome in Heart Failure

(2021) Jimin Wu et al.   Frontiers in Physiology

Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3

(2020) Shiju Ye et al.   CIRCULATION RESEARCH

JNK and cardiometabolic dysfunction

(2019) Siobhan M. Craige et al.   BIOSCIENCE REPORTS

Up-regulated cathepsin C induces macrophage M1 polarization through FAK-triggered p38 MAPK/NF-κB pathway

(2019) Shahid Alam et al.   EXPERIMENTAL CELL RESEARCH

Dapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction

(2019) Nannan Zhang et al.   Cardiovascular Diabetology

Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure

(2019) Lauren B. Arendse et al.   PHARMACOLOGICAL REVIEWS

Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress

(2019) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload

(2018) Timothy D. Calamaras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Antidepressant-like effects of ginsenoside Rg5 in mice: Involving of hippocampus BDNF signaling pathway

(2017) Dawei Xu et al.   NEUROSCIENCE LETTERS

Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1

(2017) Yi-Lin Yang et al.   Cell Death & Disease

Protective Effects of Processed Ginseng and Its Active Ginsenosides on Cisplatin-Induced Nephrotoxicity: In Vitro and in Vivo Studies

(2015) Jun Yeon Park et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lipopolysaccharide (LPS)-mediated Angiopoietin-2-dependent Autocrine Angiogenesis Is Regulated by NADPH Oxidase 2 (Nox2) in Human Pulmonary Microvascular Endothelial Cells

(2015) Heather Menden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiotensin II and Vascular Injury

(2014) Augusto C. Montezano et al.   CURRENT HYPERTENSION REPORTS

Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation

(2013) Lei Wang et al.   CARDIOVASCULAR RESEARCH

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation

(2011) Wen Dong et al.   NUCLEIC ACIDS RESEARCH