Ciclopirox mitigates inflammatory response in LPS-induced septic shock via inactivation of SORT1-mediated wnt/β-Catenin signaling pathway

Revealing potential diagnostic gene biomarkers of septic shock based on machine learning analysis

(2022) Yonghua Fan et al.   BMC INFECTIOUS DISEASES

Reduction in Ventilation-Induced Diaphragmatic Mitochondrial Injury through Hypoxia-Inducible Factor 1α in a Murine Endotoxemia Model

(2022) Li-Fu Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Impact of Inflammatory Stimuli on Xylosyltransferase-I Regulation in Primary Human Dermal Fibroblasts

(2022) Thanh-Diep Ly et al.   Biomedicines

Venous Thromboembolism in Sepsis: From Bench to Bedside

(2022) Eleonora Galli et al.   Biomedicines

Identifying Potential Effective Diagnostic and Prognostic Biomarkers in Sepsis by Bioinformatics Analysis and Validation

(2022) Xu Huang et al.   International Journal of General Medicine

Ciclopirox inhibits NLRP3 inflammasome activation via protecting mitochondria and ameliorates imiquimod-induced psoriatic inflammation in mice

(2022) Shuli Liang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reposition of the Fungicide Ciclopirox for Cancer Treatment

(2021) Zhu Huang et al.   Recent Patents on Anti-Cancer Drug Discovery

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

(2021) Laura Evans et al.   INTENSIVE CARE MEDICINE

Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation

(2020) Xiaorong Hou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

AOC4P suppresses viability and invasion and induces apoptosis in NSCLC cells by inhibiting the Wnt/β-catenin pathway

(2020) Fengbo Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

High‐content screening identifies inhibitors of oxidative stress‐induced parthanatos: cytoprotective and anti‐inflammatory effects of ciclopirox

(2020) Zsolt Regdon et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sortilin promotes glioblastoma invasion and mesenchymal transition through GSK-3β/β-catenin/twist pathway

(2019) Wei Yang et al.   Cell Death & Disease

Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor

(2019) Nuria Fabri-Faja et al.   ANALYTICA CHIMICA ACTA

Production of IFNβ by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNβ-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis

(2019) Magdalena Howe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent

(2019) Hongxuan Feng et al.   Acta Pharmaceutica Sinica B

Erastin Inhibits Septic Shock and Inflammatory Gene Expression via Suppression of the NF-κB Pathway

(2019) Byung Moo Oh et al.   Journal of Clinical Medicine

A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice

(2018) Ruben Zamora et al.   PLoS Computational Biology

Mitigation of sepsis-induced inflammatory responses and organ injury through targeting Wnt/β-catenin signaling

(2017) Archna Sharma et al.   Scientific Reports

Essential Role for Ethanolamine Plasmalogen Hydrolysis in Bacterial Lipopolysaccharide Priming of Macrophages for Enhanced Arachidonic Acid Release

(2017) Luis Gil-de-Gómez et al.   Frontiers in Immunology

Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1

(2016) Jibiao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ciclopirox enhances pancreatic islet health by modulating the unfolded protein response in diabetes

(2016) Chrysovalantou Mihailidou et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Identification of adults with sepsis in the prehospital environment: a systematic review

(2016) Michael A Smyth et al.   BMJ Open

Caspase-1 Independent Viral Clearance and Adaptive Immunity Against Mucosal Respiratory Syncytial Virus Infection

(2015) Ye Ri Shim et al.   Immune Network

Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis

(2014) Martin B. Mortensen et al.   JOURNAL OF CLINICAL INVESTIGATION

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Initial Emergency Department Diagnosis and Management of Adult Patients with Severe Sepsis and Septic Shock

(2012) Sarah M Perman et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Immunomodulation of voltage-dependent K+channels in macrophages: molecular and biophysical consequences

(2010) Núria Villalonga et al.   JOURNAL OF GENERAL PHYSIOLOGY

The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice

(2010) Hiroko Tsutsui et al.   Gastroenterology Research and Practice

The humanurocortin 2gene is regulated by hypoxia: identification of a hypoxia-responsive element in the 3′-flanking region

(2009) Katrin Bühler et al.   BIOCHEMICAL JOURNAL

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Wnt Pathway

(2008) Sarah Jane George   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY