Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1
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Title
Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 1, Pages 146-160
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2016-11-24
DOI
10.1074/jbc.m116.762005
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- (2016) Wesam Bahitham et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
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- Sortilin deficiency improves the metabolic phenotype and reduces hepatic steatosis of mice subjected to diet-induced obesity
- (2015) Liane Rabinowich et al. JOURNAL OF HEPATOLOGY
- ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading–induced autophagy
- (2015) Shuhui Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
- (2014) Suryaprakash Raichur et al. Cell Metabolism
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- (2014) Camilla Gustafsen et al. Cell Metabolism
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- (2014) Jinghua Bie et al. JOURNAL OF LIPID RESEARCH
- Lysosomal cholesterol accumulation: driver on the road to inflammation during atherosclerosis and non-alcoholic steatohepatitis
- (2014) T. Hendrikx et al. Obesity Reviews
- Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis
- (2013) Jiesi Xu et al. HEPATOLOGY
- Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice
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- Cooperation between hepatic cholesteryl ester hydrolase and scavenger receptor BI for hydrolysis of HDL-CE
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- (2012) Jose A. Chavez et al. Cell Metabolism
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- (2012) Ariel D. Quiroga et al. HEPATOLOGY
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- A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice
- (2010) Anne S. Henkel et al. JOURNAL OF LIPID RESEARCH
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
- (2010) Kiran Musunuru et al. NATURE
- Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes
- (2009) Kerry W.S. Ko et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The Vps10p-domain receptor family
- (2009) Guido Hermey CELLULAR AND MOLECULAR LIFE SCIENCES
- Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH
- (2009) Francisco Caballero et al. JOURNAL OF HEPATOLOGY
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
- (2009) Sekar Kathiresan et al. NATURE GENETICS
- Sortilin mediates the lysosomal targeting of cathepsins D and H
- (2008) Maryssa Canuel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
- (2008) Kristiaan Wouters et al. HEPATOLOGY
- Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport
- (2008) Bin Zhao et al. JOURNAL OF LIPID RESEARCH
- Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
- (2008) Sekar Kathiresan et al. NATURE GENETICS
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- (2007) Maryssa Canuel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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