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Title
“Hurdles race for CAR T‐cell therapy in digestive tract cancer”
Authors
Keywords
-
Journal
IMMUNOLOGICAL REVIEWS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-09-11
DOI
10.1111/imr.13273
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Note: Only part of the references are listed.- Colorectal cancer statistics, 2023
- (2023) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- KEYNOTE-B79 phase 1b trial to evaluate the allogeneic CAR T-cells CYAD-101 and pembrolizumab in refractory metastatic colorectal cancer patients.
- (2022) Richard D. Kim et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical Grade Manufacture of CYAD-101, a NKG2D-based, First in Class, Non–Gene-edited Allogeneic CAR T-Cell Therapy
- (2022) Alexandre Michaux et al. JOURNAL OF IMMUNOTHERAPY
- Decade-long leukaemia remissions with persistence of CD4+ CAR T cells
- (2022) J. Joseph Melenhorst et al. NATURE
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- (2022) Yuichiro Doki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results
- (2022) Changsong Qi et al. NATURE MEDICINE
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- (2022) Amanda V. Finck et al. NATURE MEDICINE
- A carcinoembryonic antigen-specific cell therapy selectively targets tumor cells with HLA loss of heterozygosity in vitro and in vivo
- (2022) Mark L. Sandberg et al. Science Translational Medicine
- Multicenter phase Ib trial in the U.S. of salvage CT041 CLDN18.2-specific chimeric antigen receptor T-cell therapy for patients with advanced gastric and pancreatic adenocarcinoma.
- (2022) Gregory P. Botta et al. JOURNAL OF CLINICAL ONCOLOGY
- A phase 1 study of ADI-001: Anti-CD20 CAR-engineered allogeneic gamma delta (γδ) T cells in adults with B-cell malignancies.
- (2022) Sattva Swarup Neelapu et al. JOURNAL OF CLINICAL ONCOLOGY
- Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
- (2022) Lacey J. Padrón et al. NATURE MEDICINE
- Gamma Delta T-Cell Based Cancer Immunotherapy: Past-Present-Future
- (2022) José Saura-Esteller et al. Frontiers in Immunology
- CAR-NK Cells: A Chimeric Hope or a Promising Therapy?
- (2022) Mohamad Sabbah et al. Cancers
- Global burden and temporal trends in incidence and mortality of oesophageal cancer
- (2022) Bolun Zhou et al. Journal of Advanced Research
- The future of engineered immune cell therapies
- (2022) Darrell J. Irvine et al. SCIENCE
- Updated data from alloSHRINK phase I first-in-human study evaluating CYAD-101, an innovative non-gene edited allogeneic CAR-T in mCRC.
- (2021) Hans Prenen et al. JOURNAL OF CLINICAL ONCOLOGY
- CAR T cells in solid tumors: challenges and opportunities
- (2021) Faroogh Marofi et al. Stem Cell Research & Therapy
- Development of CAR-T Cell Persistence in Adoptive Immunotherapy of Solid Tumors
- (2021) Jiaqiao Fan et al. Frontiers in Oncology
- HER2 Expression, Test Deviations, and Their Impact on Survival in Metastatic Gastric Cancer: Results From the Prospective Multicenter VARIANZ Study
- (2021) Ivonne Haffner et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2021) Ronan J. Kelly et al. NEW ENGLAND JOURNAL OF MEDICINE
- Leukocyte Heterogeneity in Pancreatic Ductal Adenocarcinoma: Phenotypic and Spatial Features Associated with Clinical Outcome
- (2021) Shannon M. Liudahl et al. Cancer Discovery
- Assessment of Pembrolizumab Therapy for the Treatment of Microsatellite Instability–High Gastric or Gastroesophageal Junction Cancer Among Patients in the KEYNOTE-059, KEYNOTE-061, and KEYNOTE-062 Clinical Trials
- (2021) Joseph Chao et al. JAMA Oncology
- P-258 Clinical study of PD-1 disrupted anti-MUC1 CAR-T cells in patients with advanced oesophageal cancer
- (2021) S. Chen et al. ANNALS OF ONCOLOGY
- New CARs on and off the road: challenges and new developments in CAR-T cell therapy
- (2021) Marc Wehrli et al. CURRENT OPINION IN PHARMACOLOGY
- Pancreatic Cancer
- (2021) Wungki Park et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Phase I experience with first in class TnMUC1 targeted chimeric antigen receptor T-cells in patients with advanced TnMUC1 positive solid tumors.
- (2021) Rodolfo Gutierrez et al. JOURNAL OF CLINICAL ONCOLOGY
- Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study
- (2021) Jong-Mu Sun et al. LANCET
- First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial
- (2021) Yelena Y Janjigian et al. LANCET
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- (2021) Hui Lu et al. Frontiers in Oncology
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- (2021) Thomas J. Ettrich et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
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- (2021) Wungki Park et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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- (2018) Michael J. Overman et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2017) Wei Xia Ang et al. Oncotarget
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- (2017) Kaichao Feng et al. Protein & Cell
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- (2015) A. Morello et al. Cancer Discovery
- ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
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- Unmet needs and challenges in gastric cancer: The way forward
- (2014) Florian Lordick et al. CANCER TREATMENT REVIEWS
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- (2014) Michele Orditura WORLD JOURNAL OF GASTROENTEROLOGY
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- (2014) M. Hudecek et al. Cancer Immunology Research
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- (2011) D.-G. Song et al. BLOOD
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- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
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- Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
- (2010) Yung-Jue Bang et al. LANCET
- Oligomeric forms of single chain immunoglobulin (scIgG)
- (2010) Thomas Schirrmann et al. mAbs
- T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
- (2010) Maria R Parkhurst et al. MOLECULAR THERAPY
- Bevacizumab in Combination With Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study
- (2008) Leonard B. Saltz et al. JOURNAL OF CLINICAL ONCOLOGY
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