The copper-catalyzed asymmetric construction of a dispiropyrrolidine skeleton via 1,3-dipolar cycloaddition of azomethine ylides to α-alkylidene succinimides

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

(2014) Rishikesh Narayan et al.   ACCOUNTS OF CHEMICAL RESEARCH

PyBidine-Cu(OTf)2-Catalyzed Asymmetric [3+2] Cycloaddition with Imino Esters: Harmony of Cu-Lewis Acid and Imidazolidine-NH Hydrogen Bonding in Concerto Catalysis

(2014) Takayoshi Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PyBidine/Copper Catalyst: Asymmetricexo′-Selective [3+2] Cycloaddition using Imino Ester and Electrophilic Indole

(2014) Atsuko Awata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A rapid and divergent access to chiral azacyclic nucleoside analogues via highly enantioselective 1,3-dipolar cycloaddition of β-nucleobase substituted acrylates

(2014) Qi-Liang Yang et al.   CHEMICAL COMMUNICATIONS

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

(2014) Javier Adrio et al.   CHEMICAL COMMUNICATIONS

Natural Products as Source of Potential Dengue Antivirals

(2014) Róbson Teixeira et al.   MOLECULES

Enantioselective Synthesis of α-Heteroarylpyrrolidines by Copper-Catalyzed 1,3-Dipolar Cycloaddition of α-Silylimines

(2014) Ana Pascual-Escudero et al.   ORGANIC LETTERS

Discovery of Inhibitors of the Wnt and Hedgehog Signaling Pathways through the Catalytic Enantioselective Synthesis of an Iridoid-Inspired Compound Collection

(2013) Hiroshi Takayama et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling

(2013) Rishikesh Narayan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient construction of highly functionalized spiro[γ-butyrolactone-pyrrolidin-3,3′-oxindole] tricyclic skeletons via an organocatalytic 1,3-dipolar cycloaddition

(2013) Long Wang et al.   CHEMICAL COMMUNICATIONS

Enantioselective synthesis of 4-aminopyrrolidine-2,4-dicarboxylate derivatives via Ag-catalyzed cycloaddition of azomethine ylides with alkylidene azlactones

(2013) María González-Esguevillas et al.   CHEMICAL COMMUNICATIONS

exo-Selective construction of spiro-[butyrolactone-pyrrolidine] via 1,3-dipolar cycloaddition of azomethine ylides with α-methylene-γ-butyrolactone catalyzed by Cu(i)/DTBM-BIPHEP

(2013) Qing-Hua Li et al.   CHEMICAL COMMUNICATIONS

Asymmetric construction of fluorinated imidazolidines via Cu(i)-catalyzed exo′-selective 1,3-dipolar cycloaddition of azomethine ylides with fluorinated imines

(2013) Qing-Hua Li et al.   CHEMICAL COMMUNICATIONS

1,3-Dipolar Cycloaddition-based Synthesis of Diverse Heterocyclic Scaffolds

(2013) Wei Zhang   CHEMISTRY LETTERS

Catalytic Asymmetric Construction of Quaternary α-Amino Acid Containing Pyrrolidines through 1,3-Dipolar Cycloaddition of Azomethine Ylides to α-Aminoacrylates

(2013) Zheng Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic carbene–gold(I)-catalyzed carboheterofunctionalization of alkenes with arylboronic acids

(2013) Shifa Zhu et al.   TETRAHEDRON

Synthesis and differential functionalisation of pyrrolidine and piperidine based spirodiamine scaffolds

(2013) Kamil Weinberg et al.   TETRAHEDRON

Catalytic Asymmetric Synthesis of α-Quaternary Proline Derivatives by 1,3-Dipolar Cycloaddition of α-Silylimines

(2012) Jorge Hernández-Toribio et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric exo′-Selective [3+2] Cycloaddition for Constructing Stereochemically Diversified Spiro[pyrrolidin-3,3′-oxindole]s

(2012) Atsuko Awata et al.   CHEMISTRY-A EUROPEAN JOURNAL

Reagent-Based DOS: Developing a Diastereoselective Methodology to Access Spirocyclic- and Fused Heterocyclic Ring Systems

(2012) V. Surendra Babu Damerla et al.   Chemistry-An Asian Journal

Programmable enantioselective one-pot synthesis of molecules with eight stereocenters

(2012) Marco Potowski et al.   Nature Chemical Biology

Spiro-fused Pyrrolidine, Piperidine, and Oxindole Scaffolds from Lactams

(2012) Christoph Hirschhäuser et al.   ORGANIC LETTERS

Catalytic asymmetric synthesis of highly substituted pyrrolizidines

(2012) Andrew D. Lim et al.   Chemical Science

Catalytic Asymmetric Construction of Spirocycles Containing Pyrrolidine Motifs and Spiro Quaternary Stereogenic Centers via 1,3-Dipolar Cycloaddition of Azomethine Ylides with 2-Alkylidene-Cycloketones

(2011) Tang-Lin Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Silver Amide Catalyst for the [3+2] Cycloaddition of α-Amino Esters to Olefins

(2011) Yasuhiro Yamashita et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An exo- and Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides with Alkylidene Malonates Catalyzed by a N,O-Ligand/Cu(OAc)2-Derived Chiral Complex

(2011) Ming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective construction of a 5-aza-spiro[2,4]heptane motif via catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides and ethyl cyclopropylidene acetate

(2011) Tang-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Highly efficient construction of spirocyclic chromanone–pyrrolidines via Cu(i)/TF–BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition

(2011) Tang-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

(2011) Javier Adrio et al.   CHEMICAL COMMUNICATIONS

Stereodivergency in Catalytic Asymmetric Conjugate Addition Reactions of Glycine (Ket)imines

(2011) Hun Young Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Ferrocenyl-DHIPOH/Cu(OAc)2Complex for Diastereo- and Enantioselective Catalysis of the 1,4-Addition of Glycine Derivatives to Alkylidene Malonates

(2011) Yu-Hua Shi et al.   ORGANIC LETTERS

Novel N,O-Cu(OAc)2 complex catalysed diastereo- and enantioselective 1,4-addition of glycine derivatives to alkylidene malonates

(2011) Ming Wang et al.   Catalysis Science & Technology

Bifunctional AgOAc-catalyzed asymmetric reactions

(2010) Qing-An Chen et al.   CHEMICAL COMMUNICATIONS

Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines

(2010) K. Karthikeyan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

Catalytic asymmetric 1,3-dipolar cycloaddition of N-unprotected 2-oxoindolin-3-ylidene derivatives and azomethine ylides for the construction of spirooxindole-pyrrolidines

(2010) Tang-Lin Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors

(2009) Kevin B. Sippy et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Synthesis of Heterocycles

(2008) Míriam Álvarez-Corral et al.   CHEMICAL REVIEWS

Enantioselective Copper-Catalyzed 1,3-Dipolar Cycloadditions

(2008) Levi M. Stanley et al.   CHEMICAL REVIEWS

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

(2008) S. Shangary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA