Catalytic Asymmetric exo′-Selective [3+2] Cycloaddition for Constructing Stereochemically Diversified Spiro[pyrrolidin-3,3′-oxindole]s

Scaffold-Inspired Enantioselective Synthesis of Biologically Important Spiro[pyrrolidin-3,2′-oxindoles] with Structural Diversity through Catalytic Isatin-Derived 1,3-Dipolar Cycloadditions

(2012) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene-Catalyzed Cyclization of Unsaturated Acyl Chlorides and Ketones

(2011) Li-Tao Shen et al.   ADVANCED SYNTHESIS & CATALYSIS

An Easy Entry to Optically Active Spiroindolinones: Chiral Brønsted Acid-Catalysed Pictet-Spengler Reactions of Isatins

(2011) Sara Duce et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Michael/Mannich Polycyclization Cascade of Indolyl Enones Catalyzed by Quinine-Derived Primary Amines

(2011) Quan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Michael/Cyclization Reaction Sequence: Scaffold-Inspired Synthesis of Spirooxindoles with Multiple Stereocenters

(2011) Yiming Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric [3+2] Annulation of Allylsilanes with Isatins: Synthesis of Spirooxindoles

(2011) Nadine V. Hanhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A highly organocatalytic stereoselective double Michael reaction: efficient construction of optically enriched spirocyclic oxindoles

(2011) Liang-Liang Wang et al.   CHEMICAL COMMUNICATIONS

Stereoselective synthesis of tetracyclic indolines via gold-catalyzed cascade cyclization reactions

(2011) Gianpiero Cera et al.   CHEMICAL COMMUNICATIONS

Core Structure-Based Design of Organocatalytic [3+2]-Cycloaddition Reactions: Highly Efficient and Stereocontrolled Syntheses of 3,3′-Pyrrolidonyl Spirooxindoles

(2011) Bin Tan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Michael-Alkylation Cascade: The Enantioselective Nitrocyclopropanation of Oxindoles

(2011) Fabio Pesciaioli et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Efficient Hydrogen-Bonding Catalysis of the Diels–Alder Reaction of 3-Vinylindoles and Methyleneindolinones Provides Carbazolespirooxindole Skeletons

(2011) Bin Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles

(2011) Bin Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trienamines in Asymmetric Organocatalysis: Diels−Alder and Tandem Reactions

(2011) Zhi-Jun Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Noncovalent Organocatalysis: A Powerful Tool for the Nucleophilic Epoxidation of α-Ylideneoxindoles

(2011) Chiara Palumbo et al.   ORGANIC LETTERS

Catalytic Asymmetric Construction of Spirocyclopentaneoxindoles by a Combined Ru-Catalyzed Cross-Metathesis/Double Michael Addition Sequence

(2011) Ying-Mei Li et al.   ORGANIC LETTERS

Highly Enantioselective One-Pot Synthesis of Spirocyclopentaneoxindoles Containing the Oxime Group by Organocatalyzed Michael Addition/ISOC/Fragmentation Sequence

(2011) Xiang Li et al.   ORGANIC LETTERS

Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A

(2011) Mou-Nuo Cheng et al.   ORGANIC LETTERS

Enantioselective synthesis of the spirotryprostatin A scaffold

(2011) Andrey P. Antonchick et al.   TETRAHEDRON

Enantioselective Synthesis of Spirocyclic Oxindole-β-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins

(2010) Xiao-Na Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric exo′-Selective [3+2] Cycloaddition of Iminoesters with Nitroalkenes

(2010) Takayoshi Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction

(2010) Xavier Companyó et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Tandem Reaction to Construct Six-Membered Spirocyclic Oxindoles with Multiple Chiral Centres through a Formal [2+2+2] Annulation

(2010) Kun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cornerstone Works for Catalytic 1,3-Dipolar Cycloaddition Reactions

(2010) Shuji Kanemasa   HETEROCYCLES

Direct Catalytic Asymmetric Vinylogous Mannich-Type and Michael Reactions of an α,β-Unsaturated γ-Butyrolactam under Dinuclear Nickel Catalysis

(2010) Nicholas E. Shepherd et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue

(2010) Xianxing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereo- and Enantioselective Conjugate Addition of α-Ketoesters to Nitroalkenes Catalyzed by a Chiral Ni(OAc)2Complex under Mild Conditions

(2010) Ayako Nakamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

Catalytic asymmetric 1,3-dipolar cycloaddition of N-unprotected 2-oxoindolin-3-ylidene derivatives and azomethine ylides for the construction of spirooxindole-pyrrolidines

(2010) Tang-Lin Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Quadruple Aminocatalytic Domino Reactions to Fused Carbocycles Incorporating a Spirooxindole Motif

(2010) Kun Jiang et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3′-oxindoline] Derivatives in High Optical Purity

(2010) Qiang Wei et al.   ORGANIC LETTERS

Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine

(2010) Wen-Bing Chen et al.   ORGANIC LETTERS

Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters

(2009) Giorgio Bencivenni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An efficient approach to chiral fullerene derivatives by catalytic enantioselective 1,3-dipolar cycloadditions

(2009) Salvatore Filippone et al.   Nature Chemistry

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

(2008) S. Shangary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA