GRP78 acts as a cAMP/PKA signaling modulator through the MC4R pathway in porcine embryonic development

Mitochondrial dysfunction, oxidative stress, ER stress and mitochondria-ER crosstalk alterations in a chemical rat model of Huntington's disease: Potential benefits of bezafibrate

(2023) Morgana Brondani et al.   TOXICOLOGY LETTERS

High Temperature Disrupts Organelle Distribution and Functions Affecting Meiotic Maturation in Porcine Oocytes

(2022) Song-Hee Lee et al.   Frontiers in Cell and Developmental Biology

Neddylation Inhibition Causes Impaired Mouse Embryo Quality and Blastocyst Hatching Failure Through Elevated Oxidative Stress and Reduced IL-1β

(2022) Guangping Yang et al.   Frontiers in Immunology

E2F4 regulates cell cycle to mediate embryonic development in pigs

(2022) Wen-Jie Jiang et al.   THERIOGENOLOGY

Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations

(2022) Dat P. Ha et al.   NEOPLASIA

Blastomere aggregation using phytohemagglutinin-L improves the establishment efficiency of porcine parthenogenesis-derived embryonic stem-like cell lines

(2022) Joohyeong Lee et al.   Frontiers in Cell and Developmental Biology

Epigallocatechin-3-gallate protects porcine oocytes against post-ovulatory aging through inhibition of oxidative stress

(2022) Dongjie Zhou et al.   Aging-US

Rotenone causes mitochondrial dysfunction and prevents maturation in porcine oocytes

(2022) Geun Heo et al.   PLoS One

G-Protein Coupled Receptors (GPCRs): Signaling Pathways, Characterization, and Functions in Insect Physiology and Toxicology

(2021) Nannan Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

(2021) Bas Brouwers et al.   Cell Reports

The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis

(2021) Huey-Jiun Ko et al.   Biomolecules

Impact of oxygen tension according to embryo stage of development: a prospective randomized study

(2021) C. Herbemont et al.   Scientific Reports

Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78)

(2020) Qian Lei et al.   Scientific Reports

DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation

(2020) Haolin Zhang et al.   Journal of Animal Science and Biotechnology

SIRT1 is a key regulatory target for the treatment of the endoplasmic reticulum stress-related organ damage

(2020) Fuquan Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

G Protein-Coupled Estrogen Receptor Mediates Cell Proliferation through the cAMP/PKA/CREB Pathway in Murine Bone Marrow Mesenchymal Stem Cells

(2020) Shu-Chun Chuang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of oxidative stress on oocyte competence for in vitro embryo production programs

(2020) Sandra Soto-Heras et al.   RESEARCH IN VETERINARY SCIENCE

Endoplasmic Reticulum (ER) Stress and Unfolded Protein Response (UPR) in Mammalian Oocyte Maturation and Preimplantation Embryo Development

(2019) Tao Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of the Role of the Mc4r System in Development, Growth, and Puberty of Medaka

(2019) Ruiqi Liu et al.   Frontiers in Endocrinology

Dysfunctional MDR-1 disrupts mitochondrial homeostasis in the oocyte and ovary

(2019) Haley Clark et al.   Scientific Reports

Activation of PKA/SIRT1 signaling pathway by photobiomodulation therapy reduces Aβ levels in Alzheimer's disease models

(2019) Zhan Zhang et al.   AGING CELL

Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures

(2019) Ronghui Li et al.   CELL

Multimodal transcriptional control of pattern formation in embryonic development

(2019) Nicholas C. Lammers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Basis of G Protein–Coupled Receptor Activation

(2018) William I. Weis et al.   Annual Review of Biochemistry

Pathophysiology of melanocortin receptors and their accessory proteins

(2018) T.V. Novoselova et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

MC4R Agonists: Structural Overview on Antiobesity Therapeutics

(2018) Juliana Pereira Lopes Gonçalves et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK

(2016) Daisuke Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

(2016) Michaël Cerezo et al.   CANCER CELL

Regulation, Signaling, and Physiological Functions of G-Proteins

(2016) Viktoriya Syrovatkina et al.   JOURNAL OF MOLECULAR BIOLOGY

On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development

(2015) Leonid Peshkin et al.   DEVELOPMENTAL CELL

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Melanocortin receptors in rat liver cells: change of gene expression and intracellular localization during acute-phase response

(2011) Ihtzaz Ahmed Malik et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+

(2011) Zachary Gerhart-Hines et al.   MOLECULAR CELL

Meiotic control of the APC/C: similarities & differences from mitosis

(2011) Katrina F Cooper et al.   Cell Division

The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology

(2010) Ya-Xiong Tao   ENDOCRINE REVIEWS

Genome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpoints

(2010) Ann A. Kiessling et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Evidence that human blastomere cleavage is under unique cell cycle control

(2009) Ann A. Kiessling et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions

(2008) Luciano Brocchieri et al.   BMC EVOLUTIONARY BIOLOGY

Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development

(2008) D. Dong et al.   CANCER RESEARCH