Weighted gene co‐expression network analysis and machine learning identified the lipid metabolism‐related gene LGMN as a novel biomarker for keloid

Role of LGMN in tumor development and its progression and connection with the tumor microenvironment

(2023) Safir Ullah Khan et al.   Frontiers in Molecular Biosciences

Macrophages of the M1 and M2 types play a role in keloids pathogenesis

(2022) Wael M. Seoudy et al.   International Wound Journal

The role of altered fatty acid in pathological scars and their dermal fibroblasts

(2022) Jin-Xiu Yang et al.   Chinese Journal of Traumatology

Identification and validation of HOXD3 and UNC5C as molecular signatures in keloid based on weighted gene co-expression network analysis

(2022) Hanwen Wang et al.   GENOMICS

Landscape of circulating metabolic fingerprinting for keloid

(2022) Yu Hu et al.   Frontiers in Immunology

The Mechanism of Asparagine Endopeptidase in the Progression of Malignant Tumors: A Review

(2021) Wenrui Zhang et al.   Cells

Emerging insights into the immunological aspects of keloids

(2021) Yangyiyi Yu et al.   JOURNAL OF DERMATOLOGY

Important role of mechanical microenvironment on macrophage dysfunction during keloid pathogenesis

(2021) Boya Zhou et al.   EXPERIMENTAL DERMATOLOGY

Development and validation of a novel lipid metabolism-related gene prognostic signature and candidate drugs for patients with bladder cancer

(2021) Ke Zhu et al.   Lipids in Health and Disease

Single-Cell Sequencing Analysis and Weighted Co-Expression Network Analysis Based on Public Databases Identified That TNC Is a Novel Biomarker for Keloid

(2021) Jiaheng Xie et al.   Frontiers in Immunology

Hypoxia and HIF-1α Regulate Collagen Production in Keloids

(2020) Yuanyuan Kang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models

(2020) Grace C. Limandjaja et al.   Frontiers in Cell and Developmental Biology

Mast Cells in Skin Scarring: A Review of Animal and Human Research

(2020) Sara Ud-Din et al.   Frontiers in Immunology

RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing

(2020) Jianni Wu et al.   Frontiers in Immunology

Monocytes co-cultured with reconstructed keloid and normal skin models skew towards M2 macrophage phenotype

(2019) Grace C. Limandjaja et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Mammalian legumain – A lysosomal cysteine protease with extracellular functions?

(2019) Ngoc Nguyen Lunde et al.   BIOCHIMIE

Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies

(2019) Silvian Tan et al.   Frontiers in Immunology

Imiquimod to prevent keloid recurrence postexcision: A systematic review and meta‐analysis

(2019) Tanja Klotz et al.   WOUND REPAIR AND REGENERATION

Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages

(2019) Ngoc Nguyen Lunde et al.   ATHEROSCLEROSIS

Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids

(2018) Ho Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Time series integrative analysis of RNA-Seq and miRNA expression data reveals key biologic wound healing pathways in keloid-prone individuals

(2018) Alexandros Onoufriadis et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans

(2017) Judilyn Fuentes-Duculan et al.   EXPERIMENTAL DERMATOLOGY

DSigDB: drug signatures database for gene set analysis: Fig. 1.

(2015) Minjae Yoo et al.   BIOINFORMATICS

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Roles of lipid metabolism in keloid development

(2013) Chenyu Huang et al.   Lipids in Health and Disease

Unlocking the potential of publicly available microarray data using inSilicoDb and inSilicoMerging R/Bioconductor packages

(2012) Jonatan Taminau et al.   BMC BIOINFORMATICS

Macrophages in skin injury and repair

(2011) Babak Mahdavian Delavary et al.   IMMUNOBIOLOGY

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Molecular dissection of abnormal wound healing processes resulting in keloid disease

(2009) Barbara Shih et al.   WOUND REPAIR AND REGENERATION

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS