Important role of mechanical microenvironment on macrophage dysfunction during keloid pathogenesis

The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models

(2020) Grace C. Limandjaja et al.   Frontiers in Cell and Developmental Biology

Hypertrophic scars and keloids: Overview of the evidence and practical guide for differentiating between these abnormal scars

(2020) Grace C. Limandjaja et al.   EXPERIMENTAL DERMATOLOGY

Mechanobiology of Macrophages: How Physical Factors Coregulate Macrophage Plasticity and Phagocytosis

(2019) Nikhil Jain et al.   Annual Review of Biomedical Engineering

Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies

(2019) Silvian Tan et al.   Frontiers in Immunology

Macrophages in keloid are potent at promoting the differentiation and function of regulatory T cells

(2018) Qi Jin et al.   EXPERIMENTAL CELL RESEARCH

Recent Advances in Scar Biology

(2018) Rei Ogawa   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanical forces in skin disorders

(2018) Chao-Kai Hsu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts

(2018) Chao-Kai Hsu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Engineering mechanical microenvironment of macrophage and its biomedical applications

(2018) Jing Li et al.   Nanomedicine

Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force

(2018) Kalpana Mandal et al.   ACS Nano

The clinical dynamic changes of macrophage phenotype and function in different stages of human wound healing and hypertrophic scar formation

(2018) Lin Chen et al.   International Wound Journal

Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks

(2017) Markus Friedemann et al.   Advanced Healthcare Materials

Swelling of Collagen-Hyaluronic Acid Co-Gels: An In Vitro Residual Stress Model

(2016) Victor K. Lai et al.   ANNALS OF BIOMEDICAL ENGINEERING

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Keloid progression: a stiffness gap hypothesis

(2016) Chenyu Huang et al.   International Wound Journal

Strain-dependent modulation of macrophage polarization within scaffolds

(2014) Virginia Ballotta et al.   BIOMATERIALS

Physical and mechanical regulation of macrophage phenotype and function

(2014) Frances Y. McWhorter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The effect of cyclic mechanical strain on activation of dendritic cells cultured on adhesive substrates

(2013) Jamal S. Lewis et al.   BIOMATERIALS

Mechanobiological dysregulation of the epidermis and dermis in skin disorders and in degeneration

(2013) Rei Ogawa et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Substrate Rigidity Regulates Human T Cell Activation and Proliferation

(2012) R. S. O'Connor et al.   JOURNAL OF IMMUNOLOGY

The relationship between skin stretching/contraction and pathologic scarring: The important role of mechanical forces in keloid generation

(2012) Rei Ogawa et al.   WOUND REPAIR AND REGENERATION

Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration

(2011) J. Huynh et al.   Science Translational Medicine

Mechanobiology of scarring

(2011) Rei Ogawa   WOUND REPAIR AND REGENERATION

Mechanical strain and TLR4 synergistically induce cell-specific inflammatory gene expression in intestinal smooth muscle cells and peritoneal macrophages

(2010) Sven Wehner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Differential Roles of Macrophages in Diverse Phases of Skin Repair

(2010) T. Lucas et al.   JOURNAL OF IMMUNOLOGY

Molecular dissection of abnormal wound healing processes resulting in keloid disease

(2009) Barbara Shih et al.   WOUND REPAIR AND REGENERATION

Keloid and hypertrophic scarring may result from a mechanoreceptor or mechanosensitive nociceptor disorder

(2008) Rei Ogawa   MEDICAL HYPOTHESES