Structural‐functional properties of direct‐pathway striatal neurons at early and chronic stages of dopamine denervation

DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons

(2023) Thomas Andreska et al.   Cell Reports

Non-Apoptotic Caspase-3 Activation Mediates Early Synaptic Dysfunction of Indirect Pathway Neurons in the Parkinsonian Striatum

(2022) Tim Fieblinger et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism

(2021) Laura Andreoli et al.   NEUROBIOLOGY OF DISEASE

From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease

(2020) Tiago F. Outeiro et al.   MOVEMENT DISORDERS

Delayed Spine Pruning of Direct Pathway Spiny Projection Neurons in a Mouse Model of Parkinson’s Disease

(2019) Steven M. Graves et al.   Frontiers in Cellular Neuroscience

What, If, and When to Move: Basal Ganglia Circuits and Self-Paced Action Initiation

(2019) Andreas Klaus et al.   Annual Review of Neuroscience

Differential Synaptic Remodeling by Dopamine in Direct and Indirect Striatal Projection Neurons in Pitx3−/−Mice, a Genetic Model of Parkinson's Disease

(2018) Luz M. Suarez et al.   JOURNAL OF NEUROSCIENCE

Striatonigral neurons divide into two distinct morphological-physiological phenotypes after chronic L-DOPA treatment in parkinsonian rats

(2018) T. Fieblinger et al.   Scientific Reports

The role of fibroblast growth factor 2 in drug addiction

(2018) Oren Even-Chen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Diametric neural ensemble dynamics in parkinsonian and dyskinetic states

(2018) Jones G. Parker et al.   NATURE

Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period

(2018) Ori J. Lieberman et al.   NEURON

Neuroprotection and neurorestoration as experimental therapeutics for Parkinson's disease

(2017) Veronica Francardo et al.   EXPERIMENTAL NEUROLOGY

Loss and remodeling of striatal dendritic spines in Parkinson’s disease: from homeostasis to maladaptive plasticity?

(2017) Rosa M. Villalba et al.   JOURNAL OF NEURAL TRANSMISSION

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

(2017) Irene Sebastianutto et al.   NEUROBIOLOGY OF DISEASE

Striatal Neurons Expressing D1 and D2 Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice

(2017) D. Gagnon et al.   Scientific Reports

L-DOPA Oppositely Regulates Synaptic Strength and Spine Morphology in D1 and D2 Striatal Projection Neurons in Dyskinesia

(2016) Luz M Suarez et al.   CEREBRAL CORTEX

Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists

(2016) Irene Sebastianutto et al.   NEUROBIOLOGY OF DISEASE

Differential dopaminergic regulation of inwardly rectifying potassium channel mediated subthreshold dynamics in striatal medium spiny neurons

(2016) Bo Zhao et al.   NEUROPHARMACOLOGY

Haloperidol Selectively Remodels Striatal Indirect Pathway Circuits

(2016) Luke E Sebel et al.   NEUROPSYCHOPHARMACOLOGY

Retrograde Axonal Degeneration in Parkinson Disease

(2016) Patricia Tagliaferro et al.   Journal of Parkinsons Disease

Zooming in on the small: The plasticity of striatal dendritic spines inl-DOPA-Induced dyskinesia

(2015) Tim Fieblinger et al.   MOVEMENT DISORDERS

Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism

(2014) Veronica Francardo et al.   BRAIN

Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia model

(2014) Haruo Nishijima et al.   MOVEMENT DISORDERS

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

(2014) Tim Fieblinger et al.   Nature Communications

L-DOPA Treatment Selectively Restores Spine Density in Dopamine Receptor D2–Expressing Projection Neurons in Dyskinetic Mice

(2013) Luz M. Suárez et al.   BIOLOGICAL PSYCHIATRY

Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease

(2013) Jeffrey H. Kordower et al.   BRAIN

Aberrant Restoration of Spines and their Synapses in L-DOPA-Induced Dyskinesia: Involvement of Corticostriatal but Not Thalamostriatal Synapses

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Imaging of Dopamine in PD and Implications for Motor and Neuropsychiatric Manifestations of PD

(2013) Raúl de la Fuente-Fernández   Frontiers in Neurology

Striatal D2 Receptors Regulate Dendritic Morphology of Medium Spiny Neurons via Kir2 Channels

(2012) M. Cazorla et al.   JOURNAL OF NEUROSCIENCE

Dopamine facilitates dendritic spine formation by cultured striatal medium spiny neurons through both D1 and D2 dopamine receptors

(2012) Caroline Fasano et al.   NEUROPHARMACOLOGY

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease

(2011) Veronica Francardo et al.   NEUROBIOLOGY OF DISEASE

Adenosine A2a receptor antagonists attenuate striatal adaptations following dopamine depletion

(2011) Jayms D. Peterson et al.   NEUROBIOLOGY OF DISEASE

Altered function of glutamatergic cortico-striatal synapses causes output pathway abnormalities in a chronic model of parkinsonism

(2010) Ruth Warre et al.   NEUROBIOLOGY OF DISEASE

Dopaminergic signaling in dendritic spines

(2008) Wei-Dong Yao et al.   BIOCHEMICAL PHARMACOLOGY

Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys

(2008) Rosa M. Villalba et al.   EXPERIMENTAL NEUROLOGY

A Dopaminergic Axon Lattice in the Striatum and Its Relationship with Cortical and Thalamic Terminals

(2008) J. Moss et al.   JOURNAL OF NEUROSCIENCE

Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons

(2008) T. S. Gertler et al.   JOURNAL OF NEUROSCIENCE

FGF acts as a co-transmitter through adenosine A2A receptor to regulate synaptic plasticity

(2008) Marc Flajolet et al.   NATURE NEUROSCIENCE

Molecular mechanisms of L-DOPA-induced dyskinesia

(2008) Peter Jenner   NATURE REVIEWS NEUROSCIENCE

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

(2008) W. Shen et al.   SCIENCE