The single‐cell evolution trajectory presented different hypoxia heterogeneity to reveal the carcinogenesis of genes in clear cell renal cell carcinoma: Based on multiple omics and real experimental verification

Single-cell transcriptome analysis revealing the intratumoral heterogeneity of ccRCC and validation of MT2A in pathogenesis

(2023) Jie Wang et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Improving Cancer Immunotherapy: Exploring and Targeting Metabolism in Hypoxia Microenvironment

(2022) Jinfen Wei et al.   Frontiers in Immunology

A radiogenomics biomarker based on immunological heterogeneity for non-invasive prognosis of renal clear cell carcinoma

(2022) Jiahao Gao et al.   Frontiers in Immunology

Hypoxia-Driven Effects in Cancer: Characterization, Mechanisms, and Therapeutic Implications

(2021) Rachel Shi et al.   Cells

Review of Prognostic Expression Markers for Clear Cell Renal Cell Carcinoma

(2021) Florent Petitprez et al.   Frontiers in Oncology

Modeling clear cell renal cell carcinoma and therapeutic implications

(2020) Melissa M. Wolf et al.   ONCOGENE

ANGPTL4

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Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

(2019) Ludovica Grassi et al.   Cell Death & Disease

HOTAIRM1 lncRNA is downregulated in clear cell renal cell carcinoma and inhibits the hypoxia pathway

(2019) Michael J. Hamilton et al.   CANCER LETTERS

Hypoxia: Overview on Hypoxia-Mediated Mechanisms with a Focus on the Role of HIF Genes

(2019) Alexandru Andrei Tirpe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Serum level of ANGPTL4 as a potential biomarker in renal cell carcinoma

(2017) Dong Dong et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells

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Renal cell carcinoma

(2017) James J. Hsieh et al.   Nature Reviews Disease Primers

The hypoxic tumor microenvironment: A driving force for breast cancer progression

(2016) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ANGPTL4 Correlates with NSCLC Progression and Regulates Epithelial-Mesenchymal Transition via ERK Pathway

(2016) Xiaoming Zhu et al.   LUNG

Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012

(2013) J. Ferlay et al.   EUROPEAN JOURNAL OF CANCER

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

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Determination of Angptl4 mRNA as a Diagnostic Marker of Primary and Metastatic Clear Cell Renal-Cell Carcinoma

(2010) Jérôme Verine et al.   PLoS One

Resistance to targeted therapy in renal-cell carcinoma

(2009) Brian I Rini et al.   LANCET ONCOLOGY