Single-cell transcriptome analysis revealing the intratumoral heterogeneity of ccRCC and validation of MT2A in pathogenesis

Modeling clear cell renal cell carcinoma and therapeutic implications

(2020) Melissa M. Wolf et al.   ONCOGENE

Potential New Therapeutic Approaches for Renal Cell Carcinoma

(2020) David C. Yang et al.   SEMINARS IN NEPHROLOGY

Single-Cell Transcriptomic Analysis of Tumor-Derived Fibroblasts and Normal Tissue-Resident Fibroblasts Reveals Fibroblast Heterogeneity in Breast Cancer

(2020) Aimy Sebastian et al.   Cancers

Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

(2020) Hiroaki Kasashima et al.   DEVELOPMENTAL CELL

Cancer-associated fibroblasts in gastrointestinal cancer

(2019) Hiroki Kobayashi et al.   Nature Reviews Gastroenterology & Hepatology

Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance

(2019) Micol Eleonora Fiori et al.   Molecular Cancer

Cancer-associated fibroblasts—heroes or villains?

(2019) Krystyna A. Gieniec et al.   BRITISH JOURNAL OF CANCER

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

(2019) Ela Elyada et al.   Cancer Discovery

WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

(2019) Yunhao Chen et al.   Molecular Cancer

Reversal of tumor acidosis by systemic buffering reactivates NK cells to express IFN-γ and induces NK cell-dependent lymphoma control without other immunotherapies

(2017) Johann Pötzl et al.   INTERNATIONAL JOURNAL OF CANCER

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

(2017) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Delineating cancer evolution with single-cell sequencing

(2015) Nicholas E. Navin   Science Translational Medicine

Metallothionein 2A core promoter region genetic polymorphism and its impact on the risk, tumor behavior, and recurrences of sinonasal inverted papilloma (Schneiderian papilloma)

(2015) Katarzyna Starska et al.   TUMOR BIOLOGY

Positive and negative regulators of the metallothionein gene (Review)

(2015) SHINICHIRO TAKAHASHI   Molecular Medicine Reports

Inhibition of JNK by novel curcumin analog C66 prevents diabetic cardiomyopathy with a preservation of cardiac metallothionein expression

(2014) Yonggang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Genetic polymorphism of metallothionein 2A and risk of laryngeal cancer in a Polish population

(2014) Katarzyna Starska et al.   MEDICAL ONCOLOGY

The oncoprotein HBXIP upregulates Lin28Bviaactivating TF II D to promote proliferation of breast cancer cells

(2013) Qian Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Downregulation of IFNG in CD4+ T Cells in Lung Cancer through Hypermethylation: A Possible Mechanism of Tumor-Induced Immunosuppression

(2013) Fang Wang et al.   PLoS One

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metallothionein 2A genetic polymorphisms and risk of ductal breast cancer

(2012) Anna Krześlak et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

(2012) Nicholas A. Saunders et al.   EMBO Molecular Medicine

Cellular teamwork in antibacterial innate immunity

(2012) Janelle S Ayres et al.   NATURE IMMUNOLOGY

Metallothionein 2A genetic polymorphisms and risk of prostate cancer in a Polish population

(2012) Ewa Forma et al.   Cancer Genetics

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE