A new triazolyl‐indolo‐quinoxaline induces apoptosis in gastric cancer cells by abrogating the STAT3/5 pathway through upregulation of PTPεC

Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

(2023) Milad Ashrafizadeh et al.   MEDICINAL RESEARCH REVIEWS

Discovery, Optimization, and Evaluation of Novel N-(Benzimidazol-5-yl)-1,3,4-thiadiazol-2-amine Analogues as Potent STAT3 Inhibitors for Cancer Treatment

(2023) Ru Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fangchinoline diminishes STAT3 activation by stimulating oxidative stress and targeting SHP-1 protein in multiple myeloma model

(2021) Young Yun Jung et al.   Journal of Advanced Research

Paradoxical functions of long noncoding RNAs in modulating STAT3 signaling pathway in hepatocellular carcinoma

(2021) Chakrabhavi Dhananjaya Mohan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies

(2021) Nawaf A. Alsaif et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Crocetin Imparts Antiproliferative Activity via Inhibiting STAT3 Signaling in Hepatocellular Carcinoma

(2021) Chakrabhavi Dhananjaya Mohan et al.   IUBMB LIFE

Tris(dibenzylideneacetone)dipalladium(0) (Tris DBA) Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Regulating the STAT3 Signaling Pathway

(2021) Loukik Arora et al.   Cancers

Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature

(2020) Chakrabhavi Dhananjaya Mohan et al.   SEMINARS IN CANCER BIOLOGY

STAT3 Pathway in Gastric Cancer: Signaling, Therapeutic Targeting and Future Prospects

(2020) Milad Ashrafizadeh et al.   Biology-Basel

The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy

(2020) Manoj Garg et al.   MEDICINAL RESEARCH REVIEWS

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Antitumoral activity of quinoxaline derivatives: A systematic review

(2018) M. Montana et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinoxaline-Based Scaffolds Targeting Tyrosine Kinases and Their Potential Anticancer Activity

(2016) Aliya M. S. El Newahie et al.   ARCHIV DER PHARMAZIE

Synthesis and antiproliferative efficiency of novel bis(imidazol-1-yl)vinyl-1,2,4-oxadiazoles

(2016) Kebballi N. Nandeesh et al.   NEW JOURNAL OF CHEMISTRY

Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses

(2016) Jerome Bourgeais et al.   Oncotarget

Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

(2015) Can Küçük et al.   Nature Communications

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia

(2015) Angelika Berger et al.   Oncotarget

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse

(2014) O. R. Bandapalli et al.   HAEMATOLOGICA

Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer

(2013) Sarah R. Walker et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors

(2012) Kui Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting STAT3 in gastric cancer

(2012) Andrew S Giraud et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mammary Epithelial Reconstitution with Gene-Modified Stem Cells Assigns Roles to Stat5 in Luminal Alveolar Cell Fate Decisions, Differentiation, Involution and Mammary Tumor Formation

(2010) Vida Vafaizadeh et al.   STEM CELLS