Conditional fluorescent mouse translocation reporters for ERK1/2 and AKT signaling

Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency

(2023) Geethika Arekatla et al.   DEVELOPMENTAL CELL

Live imaging approach of dynamic multicellular responses in ERK signaling during vertebrate tissue development

(2022) Tsuyoshi Hirashima   BIOCHEMICAL JOURNAL

Single cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G protein-coupled receptors

(2022) Sergei Chavez-Abiega et al.   JOURNAL OF CELL SCIENCE

Signalling dynamics, cell decisions, and homeostatic control in health and disease

(2022) Pablo Oriol Valls et al.   CURRENT OPINION IN CELL BIOLOGY

Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis

(2022) Pascal Ender et al.   DEVELOPMENTAL CELL

Control of osteoblast regeneration by a train of Erk activity waves

(2021) Alessandro De Simone et al.   NATURE

Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

(2021) Mamoru Ishii et al.   eLife

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis

(2021) Kazuhide S Okuda et al.   eLife

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

(2021) Paolo Armando Gagliardi et al.   DEVELOPMENTAL CELL

Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

(2021) Ana Martinez-Val et al.   Nature Communications

A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control

(2020) Alexander G. Goglia et al.   Cell Systems

Live Visualization of ERK Activity in the Mouse Blastocyst Reveals Lineage-Specific Signaling Dynamics

(2020) Claire S. Simon et al.   DEVELOPMENTAL CELL

Cell-Cycle-Dependent ERK Signaling Dynamics Direct Fate Specification in the Mammalian Preimplantation Embryo

(2020) Michael J. Pokrass et al.   DEVELOPMENTAL CELL

MAPK and PI3K signaling: At the crossroads of neural crest development

(2018) Colin J. Dinsmore et al.   DEVELOPMENTAL BIOLOGY

Live-cell measurements of kinase activity in single cells using translocation reporters

(2017) Takamasa Kudo et al.   Nature Protocols

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression

(2016) Gembu Maryu et al.   CELL STRUCTURE AND FUNCTION

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

(2015) Toru Hiratsuka et al.   eLife

High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells

(2014) Sergi Regot et al.   CELL

Deciphering the mechanism behind Fibroblast Growth Factor (FGF) induced biphasic signal-response profiles

(2014) Jitendra Kanodia et al.   Cell Communication and Signaling

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs

(2013) Chiara Francavilla et al.   MOLECULAR CELL

Development of an optimized backbone of FRET biosensors for kinases and GTPases

(2011) Naoki Komatsu et al.   MOLECULAR BIOLOGY OF THE CELL

Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

(2009) Wolfgang Link et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Disruption of a mitochondrial RNA-binding protein gene results in decreased cytochromebexpression and a marked reduction in ubiquinol–cytochromecreductase activity in mouse heart mitochondria

(2008) Fenghao Xu et al.   BIOCHEMICAL JOURNAL

A genetically encoded fluorescent sensor of ERK activity

(2008) C. D. Harvey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA