Development of an optimized backbone of FRET biosensors for kinases and GTPases

Reversible Dimerization ofAequorea victoriaFluorescent Proteins Increases the Dynamic Range of FRET-Based Indicators

(2010) Ippei Kotera et al.   ACS Chemical Biology

Visualization of PKA activity in plasma membrane microdomains

(2010) Charlene Depry et al.   Molecular BioSystems

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Spontaneous network activity visualized by ultrasensitive Ca2+ indicators, yellow Cameleon-Nano

(2010) Kazuki Horikawa et al.   NATURE METHODS

Bright cyan fluorescent protein variants identified by fluorescence lifetime screening

(2010) Joachim Goedhart et al.   NATURE METHODS

Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor

(2010) M. Fosbrink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

(2009) C. C. Dibble et al.   MOLECULAR AND CELLULAR BIOLOGY

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

(2009) Kosuke Yusa et al.   NATURE METHODS

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

(2009) Kazuhiro Aoki et al.   Nature Protocols

Visualization of growth signal transduction cascades in living cells with genetically encoded probes based on Forster resonance energy transfer

(2008) K. Aoki et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors

(2008) M. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genetically encoded fluorescent sensor of ERK activity

(2008) C. D. Harvey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA