Deciphering the mechanism behind Fibroblast Growth Factor (FGF) induced biphasic signal-response profiles

Cooperative Heparin-Mediated Oligomerization of Fibroblast Growth Factor-1 (FGF1) Precedes Recruitment of FGFR2 to Ternary Complexes

(2013) Alan Brown et al.   BIOPHYSICAL JOURNAL

High-dimensional Bayesian parameter estimation: Case study for a model of JAK2/STAT5 signaling

(2013) S. Hug et al.   MATHEMATICAL BIOSCIENCES

Fibroblast Growth Factor Receptor Inhibitors as a Cancer Treatment: From a Biologic Rationale to Medical Perspectives

(2013) Maria Vittoria Dieci et al.   Cancer Discovery

Measurement and Modeling of Signaling at the Single-Cell Level

(2012) Sarah E. Kolitz et al.   BIOCHEMISTRY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Highly Sulfated Nonreducing End-derived Heparan Sulfate Domains Bind Fibroblast Growth Factor-2 with High Affinity and Are Enriched in Biologically Active Fractions

(2011) Hicham Naimy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis

(2010) S. Iadevaia et al.   CANCER RESEARCH

The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

(2010) Hongyan Zhu et al.   Cell Communication and Signaling

Heparan Sulfate Acts as a Bone Morphogenetic Protein Coreceptor by Facilitating Ligand-induced Receptor Hetero-oligomerization

(2010) Wan-Jong Kuo et al.   MOLECULAR BIOLOGY OF THE CELL

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

(2010) Klementina Fon Tacer et al.   MOLECULAR ENDOCRINOLOGY

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

(2009) A. Raue et al.   BIOINFORMATICS

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling

(2008) Seiji Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY