Stretching the limits of extracellular signal-related kinase (ERK) signaling — Cell mechanosensing to ERK activation

Live imaging approach of dynamic multicellular responses in ERK signaling during vertebrate tissue development

(2022) Tsuyoshi Hirashima   BIOCHEMICAL JOURNAL

Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues

(2022) Anaïs Bailles et al.   Annual Review of Cell and Developmental Biology

FRET Visualization of Cyclic Stretch-Activated ERK via Calcium Channels Mechanosensation While Not Integrin β1 in Airway Smooth Muscle Cells

(2022) Xin Fang et al.   Frontiers in Cell and Developmental Biology

A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration

(2022) Naoya Hino et al.   DEVELOPMENTAL CELL

Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis

(2022) Pascal Ender et al.   DEVELOPMENTAL CELL

Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions

(2022) Pakorn Kanchanawong et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of osteoblast regeneration by a train of Erk activity waves

(2021) Alessandro De Simone et al.   NATURE

Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

(2021) Mamoru Ishii et al.   eLife

P120 catenin potentiates constitutive E-cadherin dimerization at the plasma membrane and regulates trans binding

(2021) Vinh Vu et al.   CURRENT BIOLOGY

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

(2021) Paolo Armando Gagliardi et al.   DEVELOPMENTAL CELL

Endocytosis in the context-dependent regulation of individual and collective cell properties

(2021) Sara Sigismund et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Substratum stiffness regulates Erk signaling dynamics through receptor-level control

(2021) Payam E. Farahani et al.   Cell Reports

Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration

(2021) Shuhao Lin et al.   Life Science Alliance

Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis

(2020) Noriyuki Kinoshita et al.   Cell Reports

ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization

(2020) Naoya Hino et al.   DEVELOPMENTAL CELL

Mechanisms of stretch-mediated skin expansion at single-cell resolution

(2020) Mariaceleste Aragona et al.   NATURE

ERK signalling: a master regulator of cell behaviour, life and fate

(2020) Hugo Lavoie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Theory of mechanochemical patterning and optimal migration in cell monolayers

(2020) Daniel Boocock et al.   Nature Physics

Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate

(2020) Henry De Belly et al.   Cell Stem Cell

Mechanochemical Feedback Loops in Development and Disease

(2019) Edouard Hannezo et al.   CELL

Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma

(2019) Andrea Palamidessi et al.   NATURE MATERIALS

Force-induced conformational changes in PIEZO1

(2019) Yi-Chih Lin et al.   NATURE

EGFR family and Src family kinase interactions: mechanics matters?

(2018) Zhongwen Chen et al.   CURRENT OPINION IN CELL BIOLOGY

A Switch-like Activation Relay of EGFR-ERK Signaling Regulates a Wave of Cellular Contractility for Epithelial Invagination

(2018) Yosuke Ogura et al.   DEVELOPMENTAL CELL

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Endocytic reawakening of motility in jammed epithelia

(2017) Chiara Malinverno et al.   NATURE MATERIALS

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning

(2017) Matthias Rübsam et al.   Nature Communications

Measuring forces and stressesin situin living tissues

(2016) Kaoru Sugimura et al.   DEVELOPMENT

Mechanism of FGF receptor dimerization and activation

(2016) Sarvenaz Sarabipour et al.   Nature Communications

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

(2015) Toru Hiratsuka et al.   eLife

Actomyosin bundles serve as a tension sensor and a platform for ERK activation

(2014) H. Hirata et al.   EMBO REPORTS

Receptor Tyrosine Kinases: Legacy of the First Two Decades

(2014) J. Schlessinger   Cold Spring Harbor Perspectives in Biology

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Mechanical waves during tissue expansion

(2012) Xavier Serra-Picamal et al.   Nature Physics

Mechanical feedback between membrane tension and dynamics

(2012) Nils C. Gauthier et al.   TRENDS IN CELL BIOLOGY

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY