Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration

Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling

(2021) Bas Ponsioen et al.   NATURE CELL BIOLOGY

ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization

(2020) Naoya Hino et al.   DEVELOPMENTAL CELL

Theory of mechanochemical patterning and optimal migration in cell monolayers

(2020) Daniel Boocock et al.   Nature Physics

MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression

(2020) Timothy J Aikin et al.   eLife

TrackMate: An open and extensible platform for single-particle tracking

(2017) Jean-Yves Tinevez et al.   METHODS

The front and rear of collective cell migration

(2016) Roberto Mayor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells

(2015) Priyank Shukla et al.   BMC GENOMICS

A molecular mechanotransduction pathway regulates collective migration of epithelial cells

(2015) Tamal Das et al.   NATURE CELL BIOLOGY

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

(2015) Toru Hiratsuka et al.   eLife

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites

(2014) Yuki Naito et al.   BIOINFORMATICS

Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells

(2014) M. Reffay et al.   NATURE CELL BIOLOGY

Epidermal growth factor, from gene organization to bedside

(2014) Fenghua Zeng et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

From wavy hair to naked proteins: The role of transforming growth factor alpha in health and disease

(2014) Bhuminder Singh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Epiregulin: Roles in normal physiology and cancer

(2014) David J. Riese et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) and proteolytic processing by a disintegrin and metalloproteinases (ADAM): A regulator of several pathways

(2014) S.R. Taylor et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation

(2013) Daisuke Nanba et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The MDCK variety pack: choosing the right strain

(2011) Joseph D Dukes et al.   BMC CELL BIOLOGY

Processive phosphorylation of ERK MAP kinase in mammalian cells

(2011) K. Aoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A simple and highly efficient transgenesis method in mice with the Tol2 transposon system and cytoplasmic microinjection

(2010) Kenta Sumiyama et al.   GENOMICS

The heparin-binding domain of HB-EGF mediates localization to sites of cell-cell contact and prevents HB-EGF proteolytic release

(2010) R. N. Prince et al.   JOURNAL OF CELL SCIENCE

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

(2009) Kosuke Yusa et al.   NATURE METHODS

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

(2009) Kazuhiro Aoki et al.   Nature Protocols

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Beyond Wavy Hairs

(2008) Marlon R. Schneider et al.   AMERICAN JOURNAL OF PATHOLOGY

Functional selectivity of EGF family peptide growth factors: Implications for cancer

(2008) Kristy J. Wilson et al.   PHARMACOLOGY & THERAPEUTICS