Tissue-resident macrophages — early passengers or drivers in the tumor niche?

Single-cell spatial landscapes of the lung tumour immune microenvironment

(2023) Mark Sorin et al.   NATURE

Single-cell spatial immune landscapes of primary and metastatic brain tumours

(2023) Elham Karimi et al.   NATURE

Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

(2023) Marit J van Elsas et al.   Journal for ImmunoTherapy of Cancer

Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles

(2022) Sarah A. Dick et al.   Science Immunology

Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer

(2022) Rodrigo Nalio Ramos et al.   CELL

Clinical relevance of tumour-associated macrophages

(2022) Mikael J. Pittet et al.   Nature Reviews Clinical Oncology

Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer

(2022) Marie Laviron et al.   Cell Reports

Macrophage diversity in cancer revisited in the era of single-cell omics

(2022) Ruo-Yu Ma et al.   TRENDS IN IMMUNOLOGY

Biology of lung macrophages in health and disease

(2022) Helena Aegerter et al.   IMMUNITY

Does tissue imprinting restrict macrophage plasticity?

(2021) Martin Guilliams et al.   NATURE IMMUNOLOGY

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

(2021) Kevin Bi et al.   CANCER CELL

A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

(2021) Sijin Cheng et al.   CELL

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

(2021) Ester Gangoso et al.   CELL

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

(2021) Ana Rita Pombo Antunes et al.   NATURE NEUROSCIENCE

Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity

(2021) Andrew Chow et al.   CANCER CELL

Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

(2021) Kevin Mulder et al.   IMMUNITY

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

(2021) María Casanova-Acebes et al.   NATURE

A single-cell and spatially resolved atlas of human breast cancers

(2021) Sunny Z. Wu et al.   NATURE GENETICS

Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models

(2021) Amaia Martinez-Usatorre et al.   Science Translational Medicine

Pro-inflammatory and proliferative microglia drive progression of glioblastoma

(2021) Hailong Liu et al.   Cell Reports

Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy

(2021) Marie Siwicki et al.   Science Immunology

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

(2020) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

(2020) Lei Zhang et al.   CELL

Determinants of Resident Tissue Macrophage Identity and Function

(2020) Camille Blériot et al.   IMMUNITY

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

(2020) Ankur Sharma et al.   CELL

Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma

(2019) Gregor Hutter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer

(2019) Sunil Singhal et al.   Science Translational Medicine

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

(2019) Luca Cassetta et al.   CANCER CELL

Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

(2019) Rapolas Zilionis et al.   IMMUNITY

Ontogeny of Tumor-Associated Macrophages

(2019) Marie Laviron et al.   Frontiers in Immunology

Macrophages orchestrate breast cancer early dissemination and metastasis

(2018) Nina Linde et al.   Nature Communications

Macrophages of distinct origins contribute to tumor development in the lung

(2018) Pierre-Louis Loyher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

(2017) Yu Zhu et al.   IMMUNITY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells

(2014) Annett Müller et al.   INTERNATIONAL JOURNAL OF CANCER

Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature

(2012) Qiong-wen Zhang et al.   PLoS One