Role of Inflammatory Processes in the Brain-Body Relationship Underlying Hypertension

The Regulatory Effect of the Paraventricular Nucleus on Hypertension

(2023) Hanyu Xi et al.   NEUROENDOCRINOLOGY

Neuroimmune axis of cardiovascular control: mechanisms and therapeutic implications

(2022) Daniela Carnevale   Nature Reviews Cardiology

Hypertension, Neurovascular Dysfunction, and Cognitive Impairment

(2022) Monica M. Santisteban et al.   HYPERTENSION

Periodontitis aggravates kidney injury by upregulating STAT1 expression in a mouse model of hypertension

(2021) Qin Yang et al.   FEBS Open Bio

The Renin-Angiotensin System in the Central Nervous System and Its Role in Blood Pressure Regulation

(2020) Pablo Nakagawa et al.   CURRENT HYPERTENSION REPORTS

Brain Angiotensin Type-1 and Type-2 Receptors in Physiological and Hypertensive Conditions: Focus on Neuroinflammation

(2020) Khalid Elsaafien et al.   CURRENT HYPERTENSION REPORTS

Endothelium-Macrophage Crosstalk Mediates Blood-Brain Barrier Dysfunction in Hypertension

(2020) Monica M. Santisteban et al.   HYPERTENSION

An Angiotensin-responsive Connection from the Lamina Terminalis to the Paraventricular Nucleus of the Hypothalamus Evokes Vasopressin Secretion to Increase Blood Pressure in Mice

(2020) Charles J. Frazier et al.   JOURNAL OF NEUROSCIENCE

Critical Role of the Interaction Gut Microbiota – Sympathetic Nervous System in the Regulation of Blood Pressure

(2019) Marta Toral et al.   Frontiers in Physiology

Periodontitis is associated with hypertension: a systematic review and meta-analysis

(2019) Eva Muñoz Aguilera et al.   CARDIOVASCULAR RESEARCH

Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy

(2019) Marta Czesnikiewicz-Guzik et al.   EUROPEAN HEART JOURNAL

Blood-borne interleukin-1β acts on the subfornical organ to upregulate the sympathoexcitatory milieu of the hypothalamic paraventricular nucleus

(2018) Shun-Guang Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology

(2018) Steven J. Forrester et al.   PHYSIOLOGICAL REVIEWS

Hypertension-Linked Pathophysiological Alterations in the GutNovelty and Significance

(2016) Monica M. Santisteban et al.   CIRCULATION RESEARCH

Increased Systolic and Diastolic Blood Pressure Is Associated With Altered Gut Microbiota Composition and Butyrate Production in Early PregnancyNovelty and Significance

(2016) Luisa F. Gomez-Arango et al.   HYPERTENSION

Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus control cardiovascular reactivity and anxiety-like behavior in male mice

(2016) Lei Wang et al.   PHYSIOLOGICAL GENOMICS

The Sympathetic Nervous System in Hypertension: Back to the Future?

(2015) Murray Esler   CURRENT HYPERTENSION REPORTS

Endothelial dysfunction in systemic sclerosis

(2014) Nezam Altorok et al.   CURRENT OPINION IN RHEUMATOLOGY

Interleukin-1β induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood–brain barrier model

(2014) Josephine Labus et al.   JOURNAL OF NEUROSCIENCE METHODS

Obesity induces neuroinflammation mediated by altered expression of the renin–angiotensin system in mouse forebrain nuclei

(2014) Annette D. de Kloet et al.   PHYSIOLOGY & BEHAVIOR

Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight Junctions

(2014) Keith D. Rochfort et al.   PLoS One

Subfornical Organ Mediates Sympathetic and Hemodynamic Responses to Blood-Borne Proinflammatory Cytokines

(2013) Shun-Guang Wei et al.   HYPERTENSION

Nucleus of the Solitary Tract (Pro)Renin Receptor-Mediated Antihypertensive Effect Involves Nuclear Factor-κB-Cytokine Signaling in the Spontaneously Hypertensive Rat

(2013) Jasenka Zubcevic et al.   HYPERTENSION

Neuron-Specific (Pro)renin Receptor Knockout Prevents the Development of Salt-Sensitive Hypertension

(2013) Wencheng Li et al.   HYPERTENSION

Circulating Angiotensin II Gains Access to the Hypothalamus and Brain Stem During Hypertension via Breakdown of the Blood–Brain Barrier

(2013) Vinicia Campana Biancardi et al.   HYPERTENSION

Psoriasis and metabolic syndrome: A systematic review and meta-analysis of observational studies

(2013) April W. Armstrong et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

(2013) Jennifer L. Pluznick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Psoriasis and Major Adverse Cardiovascular Events: A Systematic Review and Meta‐Analysis of Observational Studies

(2013) Ehrin J. Armstrong et al.   Journal of the American Heart Association

A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity

(2012) Aline M. Hilzendeger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The risk of cardiovascular disease in systemic sclerosis: a population-based cohort study

(2012) Ada Man et al.   ANNALS OF THE RHEUMATIC DISEASES

Brain-Targeted (Pro)renin Receptor Knockdown Attenuates Angiotensin II–Dependent Hypertension

(2012) Wencheng Li et al.   HYPERTENSION

Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation

(2012) Kay LH Wu et al.   Journal of Neuroinflammation

Upregulation of the Renin-Angiotensin-Aldosterone-Ouabain System in the Brain Is the Core Mechanism in the Genesis of All Types of Hypertension

(2012) Hakuo Takahashi   International Journal of Hypertension

Inflammatory cytokines in paraventricular nucleus modulate sympathetic activity and cardiac sympathetic afferent reflex in rats

(2011) Z. Shi et al.   Acta Physiologica

The sympathetic nervous system through the ages: from Thomas Willis to resistant hypertension

(2011) Murray Esler   EXPERIMENTAL PHYSIOLOGY

Angiotensin II–Induced Hypertension Is Modulated by Nuclear Factor-κB in the Paraventricular Nucleus

(2011) Jeffrey P. Cardinale et al.   HYPERTENSION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiovascular Actions of Leptin in the Subfornical Organ are Abolished by Diet-Induced Obesity

(2011) P. M. Smith et al.   JOURNAL OF NEUROENDOCRINOLOGY

Under pressure: the search for the essential mechanisms of hypertension

(2011) Thomas M Coffman   NATURE MEDICINE

Contributions of vascular inflammation in the brainstem for neurogenic hypertension

(2011) Hidefumi Waki et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Involvement of the Brain (Pro)renin Receptor in Cardiovascular Homeostasis

(2010) Zhiying Shan et al.   CIRCULATION RESEARCH

Neurogenic hypertension

(2010) Julian F. R. Paton et al.   EXPERIMENTAL PHYSIOLOGY

Brain Microglial Cytokines in Neurogenic Hypertension

(2010) Peng Shi et al.   HYPERTENSION

Angiotensin II induced cerebral microvascular inflammation and increased blood–brain barrier permeability via oxidative stress

(2010) M. Zhang et al.   NEUROSCIENCE

Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension

(2009) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

Brain tumour necrosis factor-  modulates neurotransmitters in hypothalamic paraventricular nucleus in heart failure

(2009) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

The Biology of the (Pro)Renin Receptor

(2009) G. Nguyen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Hypertension Paradox — More Uncontrolled Disease despite Improved Therapy

(2009) Aram V. Chobanian   NEW ENGLAND JOURNAL OF MEDICINE

Altered central catecholaminergic transmission and cardiovascular disease

(2008) S. Kasparov et al.   EXPERIMENTAL PHYSIOLOGY

Leptin Signaling in the Nucleus Tractus Solitarii Increases Sympathetic Nerve Activity to the Kidney

(2008) Allyn L. Mark et al.   HYPERTENSION

Signalling across the blood brain barrier by angiotensin II: novel implications for neurogenic hypertension

(2008) Julian F. R. Paton et al.   JOURNAL OF MOLECULAR MEDICINE-JMM