Blood-borne interleukin-1β acts on the subfornical organ to upregulate the sympathoexcitatory milieu of the hypothalamic paraventricular nucleus

Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure

(2016) Shun-Guang Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Interleukin-1 Blockade in Acute Decompensated Heart Failure

(2016) Benjamin W. Van Tassell et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of brain aldosterone and mineralocorticoid receptors in aldosterone-salt hypertension in rats

(2016) H.-W. Wang et al.   NEUROSCIENCE

Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus control cardiovascular reactivity and anxiety-like behavior in male mice

(2016) Lei Wang et al.   PHYSIOLOGICAL GENOMICS

Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner

(2015) Huixia Li et al.   CELL CYCLE

Proinflammatory Cytokines Upregulate Sympathoexcitatory Mechanisms in the Subfornical Organ of the Rat

(2015) S.-G. Wei et al.   HYPERTENSION

Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

(2015) Rahul B Dange et al.   Journal of Neuroinflammation

Pentoxifylline in Heart Failure: A Meta-Analysis of Clinical Trials

(2014) Sébastien Champion et al.   Cardiovascular Therapeutics

Knockdown of mineralocorticoid or angiotensin II type 1 receptor gene expression in the paraventricular nucleus prevents angiotensin II hypertension in rats

(2014) Aidong Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pentoxifylline alleviates hypertension in metabolic syndrome: effect on low-grade inflammation and angiotensin system

(2014) A. Azhar et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Subfornical Organ Mediates Sympathetic and Hemodynamic Responses to Blood-Borne Proinflammatory Cytokines

(2013) Shun-Guang Wei et al.   HYPERTENSION

Inhibition of TNF in the Brain Reverses Alterations in RAS Components and Attenuates Angiotensin II-Induced Hypertension

(2013) Srinivas Sriramula et al.   PLoS One

Inflammatory Cytokines in Heart Failure: Mediators and Markers

(2012) Lars Gullestad et al.   CARDIOLOGY

Median preoptic nucleus and subfornical organ drive renal sympathetic nerve activity via a glutamatergic mechanism within the paraventricular nucleus

(2011) Tamra Llewellyn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Central TNF inhibition results in attenuated neurohumoral excitation in heart failure: a role for superoxide and nitric oxide

(2011) Anuradha Guggilam et al.   BASIC RESEARCH IN CARDIOLOGY

Angiotensin-II-induced reactive oxygen species along the SFO-PVN-RVLM pathway: implications in neurogenic hypertension

(2011) V.A. Braga et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension

(2011) Srinivas Sriramula et al.   CARDIOVASCULAR RESEARCH

The role of the subfornical organ in angiotensin II-salt hypertension in the rat

(2011) John W. Osborn et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin II–Induced Hypertension Is Modulated by Nuclear Factor-κB in the Paraventricular Nucleus

(2011) Jeffrey P. Cardinale et al.   HYPERTENSION

Peroxisome Proliferator-Activated Receptor-γ Regulates Inflammation and Renin-Angiotensin System Activity in the Hypothalamic Paraventricular Nucleus and Ameliorates Peripheral Manifestations of Heart Failure

(2011) Yang Yu et al.   HYPERTENSION

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peroxisome-Proliferator-Activated Receptor Gamma Coactivator 1   Contributes to Dysmyelination in Experimental Models of Huntington's Disease

(2011) Z. Xiang et al.   JOURNAL OF NEUROSCIENCE

Proinflammatory cytokines in heart failure: double-edged swords

(2010) Mona Hedayat et al.   HEART FAILURE REVIEWS

Tumor Necrosis Factor-α Antagonist Etanercept Decreases Blood Pressure and Protects the Kidney in a Mouse Model of Systemic Lupus Erythematosus

(2010) Marcia Venegas-Pont et al.   HYPERTENSION

Brain Microglial Cytokines in Neurogenic Hypertension

(2010) Peng Shi et al.   HYPERTENSION

Region-specific projections from the subfornical organ to the paraventricular hypothalamic nucleus in the rat

(2010) H. Kawano et al.   NEUROSCIENCE

TNF-α in Hypothalamic Paraventricular Nucleus Contributes to Sympathoexcitation in Heart Failure by Modulating AT1 Receptor and Neurotransmitters

(2010) Yu-Ming Kang et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Brain tumour necrosis factor-  modulates neurotransmitters in hypothalamic paraventricular nucleus in heart failure

(2009) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

Oxidative Stress and Hypertension

(2009) David G. Harrison et al.   MEDICAL CLINICS OF NORTH AMERICA

Inhibition of brain proinflammatory cytokine synthesis reduces hypothalamic excitation in rats with ischemia-induced heart failure

(2008) Yu-Ming Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Scavenging superoxide selectively in mouse forebrain is associated with improved cardiac function and survival following myocardial infarction

(2008) Timothy E. Lindley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cross-talk between cytokines and renin-angiotensin in hypothalamic paraventricular nucleus in heart failure: role of nuclear factor- B

(2008) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

Cytokine blockade attenuates sympathoexcitation in heart failure: Cross-talk between nNOS, AT-1R and cytokines in the hypothalamic paraventricular nucleus

(2008) Anuradha Guggilam et al.   EUROPEAN JOURNAL OF HEART FAILURE

The paraventricular nucleus of the hypothalamus – a potential target for integrative treatment of autonomic dysfunction

(2008) Alastair V Ferguson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Angiotensin II–Triggered p44/42 Mitogen-Activated Protein Kinase Mediates Sympathetic Excitation in Heart Failure Rats

(2008) Shun-Guang Wei et al.   HYPERTENSION

Involvement of Tumor Necrosis Factor-α in Angiotensin II–Mediated Effects on Salt Appetite, Hypertension, and Cardiac Hypertrophy

(2008) Srinivas Sriramula et al.   HYPERTENSION