Image-guided subject-specific modeling of glymphatic transport and amyloid deposition

Human brain solute transport quantified by glymphatic MRI-informed biophysics during sleep and sleep deprivation

(2023) Vegard Vinje et al.   Fluids and Barriers of the CNS

Whole‐brain mapping of mouse CSF flow via HEAP‐METRIC phase‐contrast MRI

(2022) Juchen Li et al.   MAGNETIC RESONANCE IN MEDICINE

Patient-Specific Modeling Could Predict Occurrence of Pediatric Stroke

(2022) John D. Horn et al.   Frontiers in Physiology

Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model

(2022) Ravi Teja Kedarasetti et al.   Fluids and Barriers of the CNS

A novel method for improving the accuracy of MR-derived patient-specific vascular models using X-ray angiography

(2022) John D. Horn et al.   ENGINEERING WITH COMPUTERS

The glymphatic system: Current understanding and modeling

(2022) Tomas Bohr et al.   iScience

Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain

(2021) Daniel E. Troyetsky et al.   Scientific Reports

Image-based patient-specific flow simulations are consistent with stroke in pediatric cerebrovascular disease

(2021) Shaolie S. Hossain et al.   Biomechanics and Modeling in Mechanobiology

Patient specific, imaging-informed modeling of rhenium-186 nanoliposome delivery via convection-enhanced delivery in glioblastoma multiforme

(2021) Ryan T Woodall et al.   Biomedical Physics & Engineering Express

Quantitative analysis of macroscopic solute transport in the murine brain

(2021) Lori A. Ray et al.   Fluids and Barriers of the CNS

Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

(2020) Sunil Koundal et al.   Scientific Reports

The Brain’s Glymphatic System: Current Controversies

(2020) Humberto Mestre et al.   TRENDS IN NEUROSCIENCES

Light sheet fluorescence microscopy of optically cleared brains for studying the glymphatic system

(2020) Nicholas B Bèchet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Apparent diffusion coefficient estimates based on 24 hours tracer movement support glymphatic transport in human cerebral cortex

(2020) Lars Magnus Valnes et al.   Scientific Reports

What is the "Relevant" Amyloid β 42 Concentration?

(2019) Jevgenij Raskatov   CHEMBIOCHEM

Suitably graded THB-spline refinement and coarsening: Towards an adaptive isogeometric analysis of additive manufacturing processes

(2019) Massimo Carraturo et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Voluntary running enhances glymphatic influx in awake behaving, young mice

(2018) Stephanie von Holstein-Rathlou et al.   NEUROSCIENCE LETTERS

Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

(2018) Humberto Mestre et al.   Nature Communications

Skeleton-stabilized immersogeometric analysis for incompressible viscous flow problems

(2018) Tuong Hoang et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow

(2017) Karl Erik Holter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

(2017) Qiaoli Ma et al.   Nature Communications

Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice

(2017) Xiao-fei He et al.   Frontiers in Molecular Neuroscience

Complexity of hierarchical refinement for a class of admissible mesh configurations

(2016) Annalisa Buffa et al.   COMPUTER AIDED GEOMETRIC DESIGN

THB-splines: An effective mathematical technology for adaptive refinement in geometric design and isogeometric analysis

(2016) Carlotta Giannelli et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism

(2016) Byung-Ju Jin et al.   JOURNAL OF GENERAL PHYSIOLOGY

Glymphatic solute transport does not require bulk flow

(2016) Mahdi Asgari et al.   Scientific Reports

Image-based goal-oriented adaptive isogeometric analysis with application to the micro-mechanical modeling of trabecular bone

(2015) C.V. Verhoosel et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

An immersogeometric variational framework for fluid–structure interaction: Application to bioprosthetic heart valves

(2015) David Kamensky et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Magnetic resonance imaging-based computational modelling of blood flow and nanomedicine deposition in patients with peripheral arterial disease

(2015) S. S. Hossain et al.   Journal of the Royal Society Interface

The Finite Cell Method: A Review in the Context of Higher-Order Structural Analysis of CAD and Image-Based Geometric Models

(2014) Dominik Schillinger et al.   ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING

Cerebrospinal fluid physiology: visualization of cerebrospinal fluid dynamics using the magnetic resonance imaging Time-Spatial Inversion Pulse method

(2014) Shinya Yamada   CROATIAN MEDICAL JOURNAL

Impaired Glymphatic Perfusion After Strokes Revealed by Contrast-Enhanced MRI

(2014) Thomas Gaberel et al.   STROKE

Vascular deposition patterns for nanoparticles in an inflamed patient-specific arterial tree

(2013) Shaolie S. Hossain et al.   Biomechanics and Modeling in Mechanobiology

In silicovascular modeling for personalized nanoparticle delivery

(2012) Shaolie S Hossain et al.   Nanomedicine

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Mathematical modeling of coupled drug and drug-encapsulated nanoparticle transport in patient-specific coronary artery walls

(2011) Shaolie S. Hossain et al.   COMPUTATIONAL MECHANICS

Microscopic diffusion tensor atlas of the mouse brain

(2011) Yi Jiang et al.   NEUROIMAGE

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The finite cell method for three-dimensional problems of solid mechanics

(2008) A. Düster et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING