Reprogramming Cell Identity: Past Lessons, Challenges, and Future Directions

B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors

(2023) Daniel F. Kaemena et al.   Nature Communications

T, NK, then macrophages: Recent advances and challenges in adaptive immunotherapy from human pluripotent stem cells

(2023) Su Hang et al.   DIFFERENTIATION

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation

(2023) Jiaowei Wang et al.   Cell Stem Cell

Cell maturation: Hallmarks, triggers, and manipulation

(2022) Juan R. Alvarez-Dominguez et al.   CELL

Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development

(2022) Kasey Y.C. Lau et al.   Cell Stem Cell

Embryo model completes gastrulation to neurulation and organogenesis

(2022) Gianluca Amadei et al.   NATURE

Genome-Scale CRISPRa Screen Identifies Novel Factors for Cellular Reprogramming

(2019) Jian Yang et al.   Stem Cell Reports

Distinct Molecular Trajectories Converge to Induce Naive Pluripotency

(2019) Hannah T. Stuart et al.   Cell Stem Cell

Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs

(2019) Sergiy Velychko et al.   Cell Stem Cell

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

(2018) Justin Brumbaugh et al.   CELL

CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency

(2018) Peng Liu et al.   Cell Stem Cell

Mesenchymal–epithelial transition in development and reprogramming

(2018) Duanqing Pei et al.   NATURE CELL BIOLOGY

Conversion of adult endothelium to immunocompetent haematopoietic stem cells

(2017) Raphael Lis et al.   NATURE

Haematopoietic stem and progenitor cells from human pluripotent stem cells

(2017) Ryohichi Sugimura et al.   NATURE

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

(2016) Alejandro Ocampo et al.   CELL

Tissue damage and senescence provide critical signals for cellular reprogramming in vivo

(2016) Lluc Mosteiro et al.   SCIENCE

Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells

(2015) Hana Benchetrit et al.   Cell Stem Cell

The oncogene c-Jun impedes somatic cell reprogramming

(2015) Jing Liu et al.   NATURE CELL BIOLOGY

CellNet: Network Biology Applied to Stem Cell Engineering

(2014) Patrick Cahan et al.   CELL

X Chromosome Reactivation Dynamics Reveal Stages of Reprogramming to Pluripotency

(2014) Vincent Pasque et al.   CELL

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner

(2014) Rodrigo L. dos Santos et al.   Cell Stem Cell

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

(2013) María Abad et al.   NATURE

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

(2013) Yael Costa et al.   NATURE

Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds

(2013) P. Hou et al.   SCIENCE

Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

(2012) Abdenour Soufi et al.   CELL

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency

(2012) V. Pasque et al.   JOURNAL OF CELL SCIENCE

Chromatin-modifying enzymes as modulators of reprogramming

(2012) Tamer T. Onder et al.   NATURE

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

(2012) Jiekai Chen et al.   NATURE GENETICS

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

(2012) M. Fidalgo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency

(2012) Anouk L. van Oosten et al.   Nature Communications

The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner

(2011) Tao Wang et al.   Cell Stem Cell

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

(2010) Miguel Angel Esteban et al.   Cell Stem Cell

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

(2010) Ronghui Li et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

iPS Cells Can Support Full-Term Development of Tetraploid Blastocyst-Complemented Embryos

(2009) Lan Kang et al.   Cell Stem Cell

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

(2008) Jose Silva et al.   PLOS BIOLOGY