Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development

The intrinsic and extrinsic effects of TET proteins during gastrulation

(2022) Saifeng Cheng et al.   CELL

¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs

(2022) Shadi Tarazi et al.   CELL

Embryo model completes gastrulation to neurulation and organogenesis

(2022) Gianluca Amadei et al.   NATURE

A single-embryo, single-cell time-resolved model for mouse gastrulation

(2021) Markus Mittnenzweig et al.   CELL

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

(2021) Alejandro Aguilera-Castrejon et al.   NATURE

Epithelial cell plasticity drives endoderm formation during gastrulation

(2021) Katharina Scheibner et al.   NATURE CELL BIOLOGY

Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre

(2021) Peng-Fei Xu et al.   Nature Communications

Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate

(2020) Evan S. Bardot et al.   MECHANISMS OF DEVELOPMENT

Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

(2020) Jesse V. Veenvliet et al.   SCIENCE

Capturing Cardiogenesis in Gastruloids

(2020) Giuliana Rossi et al.   Cell Stem Cell

MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

(2019) Hadas Keren-Shaul et al.   Nature Protocols

Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo

(2019) Bechara Saykali et al.   eLife

Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid

(2019) Berna Sozen et al.   DEVELOPMENTAL CELL

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

(2018) Leonardo Beccari et al.   NATURE

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

(2017) Sarah Ellys Harrison et al.   SCIENCE

Analysis of extraembryonic mesodermal structure formation in the absence of morphological primitive streak

(2016) Jiu-Zhen Jin et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner

(2015) Martyn Donnison et al.   DEVELOPMENTAL BIOLOGY

Cdx2Efficiently Induces Trophoblast Stem-Like Cells in Naïve, but Not Primed, Pluripotent Stem Cells

(2015) Stephanie Blij et al.   STEM CELLS AND DEVELOPMENT

Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation

(2014) Ivan Bedzhov et al.   CELL

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

(2014) S. C. van den Brink et al.   DEVELOPMENT

SOX17 links gut endoderm morphogenesis and germ layer segregation

(2014) Manuel Viotti et al.   NATURE CELL BIOLOGY

Circulation-Independent Differentiation Pathway from Extraembryonic Mesoderm toward Hematopoietic Stem Cells via Hemogenic Angioblasts

(2014) Yosuke Tanaka et al.   Cell Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

(2009) Sebastian J. Arnold et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wnt Signaling Mediates Self-Organization and Axis Formation in Embryoid Bodies

(2008) Derk ten Berge et al.   Cell Stem Cell

The Endoderm of the Mouse Embryo Arises by Dynamic Widespread Intercalation of Embryonic and Extraembryonic Lineages

(2008) Gloria S. Kwon et al.   DEVELOPMENTAL CELL

An optimized procedure for whole-mount in situ hybridization on mouse embryos and embryoid bodies

(2008) Denis Piette et al.   Nature Protocols