Ionizing radiation-induced mitophagy promotes ferroptosis by increasing intracellular free fatty acids

The multifaceted role of ferroptosis in liver disease

(2022) Junyi Chen et al.   CELL DEATH AND DIFFERENTIATION

Diet, lipids, and antitumor immunity

(2022) Hannah Prendeville et al.   Cellular & Molecular Immunology

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis

(2022) Hai-Liang Zhang et al.   NATURE CELL BIOLOGY

Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

(2022) Yu Miao et al.   EBioMedicine

Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice

(2022) Devadoss J. Samuvel et al.   Autophagy

The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming

(2022) Sophia M. Hochrein et al.   Cell Metabolism

Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer

(2022) Zaihuan Lin et al.   Redox Biology

Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction

(2022) Yoshiyuki Henning et al.   Cell Death & Disease

Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells

(2022) Gilles Rademaker et al.   Redox Biology

NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells

(2022) Hao Zhou et al.   Redox Biology

Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis

(2022) Xiaochun Yin et al.   Cell Death & Disease

BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.

(2021) Maya Z. Springer et al.   Autophagy

A Novel Therapeutic Target, BACH1, Regulates Cancer Metabolism

(2021) Joselyn Padilla et al.   Cells

Glutamine synthetase as a central element in hepatic glutamine and ammonia metabolism: novel aspects

(2021) Benedikt Frieg et al.   BIOLOGICAL CHEMISTRY

Role of iron in cancer

(2021) Konstantin Salnikow   SEMINARS IN CANCER BIOLOGY

Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

(2021) Hongrong Ding et al.   Journal of Cachexia Sarcopenia and Muscle

Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis

(2021) Ling Yang et al.   ACTA PHARMACOLOGICA SINICA

Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer

(2021) Yizeng Fan et al.   Autophagy

Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling

(2021) Linlin Gu et al.   CELL DEATH AND DIFFERENTIATION

Autophagy‐Dependent Ferroptosis as a Therapeutic Target in Cancer

(2021) Li Liu et al.   ChemMedChem

Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD-positive AML

(2021) Megan E Zavorka Thomas et al.   MOLECULAR CANCER THERAPEUTICS

The multifaceted regulation of mitophagy by endogenous metabolites

(2021) Ting Zhang et al.   Autophagy

An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis

(2021) Batuhan Yenilmez et al.   MOLECULAR THERAPY

Mice with disrupted mitochondria used to model Parkinson’s disease

(2021) Zak Doric et al.   NATURE

Targeting cancer metabolism in the era of precision oncology

(2021) Zachary E. Stine et al.   NATURE REVIEWS DRUG DISCOVERY

GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway

(2021) Lujian Zhu et al.   Oxidative Medicine and Cellular Longevity

Metal‐Polyphenol‐Network Coated Prussian Blue Nanoparticles for Synergistic Ferroptosis and Apoptosis via Triggered GPX4 Inhibition and Concurrent In Situ Bleomycin Toxification

(2021) Lulu Zhou et al.   Small

N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells

(2021) Min Shen et al.   Redox Biology

Radiofrequency Radiation and Cancer

(2021) David Robert Grimes   JAMA Oncology

Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers

(2020) Ling F. Ye et al.   ACS Chemical Biology

The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

(2020) Guang Lei et al.   CELL RESEARCH

Hepatic Transferrin Plays a Role in Systemic Iron Homeostasis and Liver Ferroptosis

(2020) Yingying Yu et al.   BLOOD

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

(2020) Pranavi Koppula et al.   Protein & Cell

Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer

(2020) Ji-Yoon Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dgat2 reduces hepatocellular carcinoma malignancy via downregulation of cell cycle-related gene expression

(2019) Yanfei Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Recent Progress in Ferroptosis Inducers for Cancer Therapy

(2019) Chen Liang et al.   ADVANCED MATERIALS

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

(2019) Lian-Jiu Su et al.   Oxidative Medicine and Cellular Longevity

Mechanisms of Action of trans Fatty Acids

(2019) Antwi-Boasiako Oteng et al.   Advances in Nutrition

Lipid droplets and mitochondria are anchored during brown adipocyte differentiation

(2019) Liujuan Cui et al.   Protein & Cell

Ferroptosis is a lysosomal cell death process

(2018) Huan Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High expression of glutamate-ammonia ligase is associated with unfavorable prognosis in patients with ovarian cancer

(2018) Shaohua Fan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nitro-fatty acid formation and metabolism

(2018) Gregory J. Buchan et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway

(2018) Jian Yin et al.   TOXICOLOGY IN VITRO

Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy

(2018) Zheqiong Tan et al.   Theranostics

DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways

(2018) Qinhua Jin et al.   Redox Biology

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis

(2018) Guy Eelen et al.   NATURE

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics

(2015) Angelika S. Rambold et al.   DEVELOPMENTAL CELL

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

(2015) Albert Herms et al.   Nature Communications

Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression

(2015) Xinyuan Xu et al.   Oncotarget

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

(2013) David Devos et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Molecular Pathways: Targeted  -Particle Radiation Therapy

(2012) K. E. Baidoo et al.   CLINICAL CANCER RESEARCH

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

(2009) Ping Gao et al.   NATURE

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

(2008) D. R. Wise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA