Histone lactylation-derived LINC01127 promotes the self-renewal of glioblastoma stem cells via the cis-regulating the MAP4K4 to activate JNK pathway

CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression

(2022) Meiling Zhang et al.   Science Translational Medicine

Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology

(2022) Bharati Mehani et al.   Acta Neuropathologica Communications

ROS-dependent HIF1α activation under forced lipid catabolism entails glycolysis and mitophagy as mediators of higher proliferation rate in cervical cancer cells

(2021) Serena Castelli et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Long Noncoding RNAs in Human Stemness and Differentiation

(2021) Fatemeh Mirzadeh Azad et al.   TRENDS IN CELL BIOLOGY

An oncolytic virus expressing IL-15/IL-15Rα combined with off-the-shelf EGFR-CAR NK cells targets glioblastoma

(2021) Rui Ma et al.   CANCER RESEARCH

Rapid reprogramming of tumour cells into cancer stem cells on double-network hydrogels

(2021) Jun Suzuka et al.   Nature Biomedical Engineering

Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-κB Pathway in BV2 Microglial Cells

(2021) Phuong Linh Nguyen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

(2021) Sunil Kumar Singh et al.   ONCOGENE

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding

(2021) Wei Wang et al.   Nature Communications

Glioblastoma Cell–Derived lncRNA-Containing Exosomes Induce Microglia to Produce Complement C5, Promoting Chemotherapy Resistance

(2021) Ziwei Li et al.   Cancer Immunology Research

Clonal ZEB1-driven mesenchymal transition promotes targetable oncologic anti-angiogenic therapy resistance

(2020) Ankush Chandra et al.   CANCER RESEARCH

Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces chemoresistance in glioblastoma

(2020) Menggui Huang et al.   Science Translational Medicine

JNK Signaling in Stem Cell Self-Renewal and Differentiation

(2020) Takashi Semba et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas

(2020) Zheng Chen et al.   Cell Death & Disease

TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα

(2020) Jianxiong Ji et al.   CELL DEATH AND DIFFERENTIATION

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clinical practice guidelines for the management of adult diffuse gliomas

(2020) Tao Jiang et al.   CANCER LETTERS

DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma

(2019) Xiangqi Meng et al.   EBioMedicine

JAK/STAT3 and NF-κB Signaling Pathways Regulate Cancer Stem-Cell Properties in Anaplastic Thyroid Cancer Cells

(2019) Ken Shiraiwa et al.   THYROID

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

(2019) Lorna R. Fiedler et al.   Cell Stem Cell

NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fyn

(2019) Saisai Guo et al.   CANCER LETTERS

Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p

(2019) Pengfei Wu et al.   Nature Communications

QKI deficiency maintains glioma stem cell stemness by activating the SHH/GLI1 signaling pathway

(2019) Bo Han et al.   CELLULAR ONCOLOGY

Metabolic regulation of gene expression by histone lactylation

(2019) Di Zhang et al.   NATURE

Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

(2018) Ling Li et al.   CANCER CELL

NF-κB in pancreatic cancer: Its key role in chemoresistance

(2018) Quanxiao Li et al.   CANCER LETTERS

Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma

(2018) Bo Han et al.   CANCER LETTERS

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression

(2018) Xiuxing Wang et al.   Cell Stem Cell

Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

(2018) Huilin Ye et al.   Cell Death & Disease

Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease

(2018) Bo Yu et al.   Theranostics

The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons

(2017) Martin Larhammar et al.   JOURNAL OF NEUROSCIENCE

Linking Long Noncoding RNA Localization and Function

(2016) Ling-Ling Chen   TRENDS IN BIOCHEMICAL SCIENCES

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

(2015) Jens U. Marquardt et al.   JOURNAL OF HEPATOLOGY

Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells

(2015) YUAN-FEI LIU et al.   Molecular Medicine Reports

Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis

(2015) Rachel J. Roth Flach et al.   Nature Communications

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

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Cis-acting noncoding RNAs: friends and foes

(2012) Sònia Guil et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells

(2012) C-H Yoon et al.   ONCOGENE

Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect

(2012) Renée F. Johnson et al.   TRENDS IN BIOCHEMICAL SCIENCES

PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

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ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth

(2011) A.-W. Liu et al.   CLINICAL CANCER RESEARCH

NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

(2011) Claudio Mauro et al.   NATURE CELL BIOLOGY

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS