Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-κB Pathway in BV2 Microglial Cells

A Novel 1,8-Naphthyridine-2-Carboxamide Derivative Attenuates Inflammatory Responses and Cell Migration in LPS-Treated BV2 Cells via the Suppression of ROS Generation and TLR4/Myd88/NF-κB Signaling Pathway

(2021) Phuong Linh Nguyen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

JNK Pathway in CNS Pathologies

(2021) Teresa de los Reyes Corrales et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation

(2020) Lei Yang et al.   NEUROBIOLOGY OF DISEASE

Anti-Inflammatory and Anti-Migratory Activities of Isoquinoline-1-Carboxamide Derivatives in LPS-Treated BV2 Microglial Cells via Inhibition of MAPKs/NF-κB Pathway

(2020) Ha Thi Thu Do et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Drug repositioning: a brief overview

(2020) Jean‐Pierre Jourdan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions

(2020) Tamer N. Jarada et al.   Journal of Cheminformatics

Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats

(2020) Zikra Zulfiqar et al.   Journal of Inflammation Research

Neuroinflammation as a Common Feature of Neurodegenerative Disorders

(2019) Leonardo Guzman-Martinez et al.   Frontiers in Pharmacology

Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells

(2019) Jiawei Zhang et al.   MOLECULAR IMMUNOLOGY

Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation

(2019) Juntao Zhang et al.   PSYCHONEUROENDOCRINOLOGY

Investigating Protein-Ligand Interactions by Solution Nuclear Magnetic Resonance Spectroscopy

(2018) Walter Becker et al.   CHEMPHYSCHEM

TNF-α induction of IL-6 in alveolar type II epithelial cells: Contributions of JNK/c-Jun/AP-1 element, C/EBPδ/C/EBP binding site and IKK/NF-κB p65/κB site

(2018) Chunguang Yan et al.   MOLECULAR IMMUNOLOGY

Ubiquitin-Conjugating Enzyme 9 Phosphorylation as a Novel Mechanism for Potentiation of the Inflammatory Response

(2016) Maria Lauda Tomasi et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain

(2016) Katarzyna Popiolek-Barczyk et al.   CURRENT MEDICINAL CHEMISTRY

Neuroinflammation pathways: a general review

(2016) Tara Shabab et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Neuroinflammation: the devil is in the details

(2016) Damon J. DiSabato et al.   JOURNAL OF NEUROCHEMISTRY

Crystal Structures of Apo- and AMP-bound Human c-Jun N-Terminal Kinase3

(2016) Yumi Eo et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Antioxidant and Anti-inflammatory Activities of N-((3,4-Dihydro-2H-benzo[h]chromene-2-yl)methyl)-4-methoxyaniline in LPS-Induced BV2 Microglial Cells

(2015) Md. Moniruzzaman et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Microglia-Mediated Inflammation and Neurodegenerative Disease

(2015) Ling Xu et al.   MOLECULAR NEUROBIOLOGY

Implications of glial nitric oxide in neurodegenerative diseases

(2015) Jose Enrique Yuste et al.   Frontiers in Cellular Neuroscience

Nitric oxide/cyclic GMP signaling regulates motility of a microglial cell line and primary microglia in vitro

(2014) Hannah Scheiblich et al.   BRAIN RESEARCH

Isoorientin attenuates lipopolysaccharide-induced pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-κB signaling pathway in BV-2 microglia

(2013) Li Yuan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Innate Immunity in the CNS: Redefining the Relationship between the CNS and Its Environment

(2013) Antoine Lampron et al.   NEURON

Microglial migration mediated by ATP-induced ATP release from lysosomes

(2012) Ying Dou et al.   CELL RESEARCH

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease

(2012) Branden Stansley et al.   Journal of Neuroinflammation

Boosting the Sensitivity of Ligand–Protein Screening by NMR of Long-Lived States

(2012) Nicola Salvi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

(2011) SE Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Saturation-Transfer Difference (STD) NMR: A Simple and Fast Method for Ligand Screening and Characterization of Protein Binding

(2011) Aldino Viegas et al.   JOURNAL OF CHEMICAL EDUCATION

Gastrodin Inhibits Expression of Inducible NO Synthase, Cyclooxygenase-2 and Proinflammatory Cytokines in Cultured LPS-Stimulated Microglia via MAPK Pathways

(2011) Ji-Nan Dai et al.   PLoS One

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications

(2010) Saba Aïd et al.   BIOCHIMIE

NO mediates microglial response to acute spinal cord injury under ATP control in vivo

(2010) Payam Dibaj et al.   GLIA

JNK: A Stress-Activated Protein Kinase Therapeutic Strategies and Involvement in Alzheimer’s and Various Neurodegenerative Abnormalities

(2010) Sidharth Mehan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxic–ischemic brain injury

(2009) Cora H. Nijboer et al.   BRAIN BEHAVIOR AND IMMUNITY

Specific activities of individual c-Jun N-terminal kinases in the brain

(2009) W. Haeusgen et al.   NEUROSCIENCE

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

ATP and NO dually control migration of microglia to nerve lesions

(2008) Yuanli Duan et al.   Developmental Neurobiology

Microglial cell migration stimulated by ATP and C5a involve distinct molecular mechanisms: Quantification of migration by a novel near-infrared method

(2008) Aaron M. Miller et al.   GLIA

Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase

(2008) Ana Pocivavsek et al.   GLIA

Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

(2008) S. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA