Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biology

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

(2021) Toshiro Hara et al.   CANCER CELL

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

(2021) David N Louis et al.   NEURO-ONCOLOGY

Identification of Distinct Immune Subtypes in Colorectal Cancer Based on the Stromal Compartment

(2020) Rongfang Shen et al.   Frontiers in Oncology

Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells

(2020) Florian Klemm et al.   CELL

Classification of diffuse lower‐grade glioma based on immunological profiling

(2020) Fan Wu et al.   Molecular Oncology

Predictive Analyses of Prognostic-Related Immune Genes and Immune Infiltrates for Glioblastoma

(2020) Ping Liang et al.   Diagnostics

Prognostic value of novel immune-related genomic biomarkers identified in head and neck squamous cell carcinoma

(2020) Yao Yao et al.   Journal for ImmunoTherapy of Cancer

New hints towards a precision medicine strategy for IDH wild-type glioblastoma

(2020) K. White et al.   ANNALS OF ONCOLOGY

Higher cytolytic score correlates with an immunosuppressive tumor microenvironment and reduced survival in glioblastoma

(2020) Alexander F. Haddad et al.   Scientific Reports

Identification of Four Immune Subtypes in Bladder Cancer Based on Immune Gene Sets

(2020) Chaozhi Tang et al.   Frontiers in Oncology

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

(2019) Timothy F. Cloughesy et al.   NATURE MEDICINE

Pseudoprogression on PSMA PET imaging of a mCRPC patient under anti-PD1 treatment

(2019) Larissa Bastos Costa et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Management of cardiac tamponade during nivolumab of lung cancer with intrapericardial bleomycin: case report

(2019) Maiko Asai et al.   Immunotherapy

Unique Case of Pseudoprogression Manifesting as Lung Cavitation After Pembrolizumab Treatment

(2019) Kentaro Masuhiro et al.   Journal of Thoracic Oncology

Determining cell type abundance and expression from bulk tissues with digital cytometry

(2019) Aaron M. Newman et al.   NATURE BIOTECHNOLOGY

The composition of T cell infiltrates varies in primary invasive breast cancer of different molecular subtypes as well as according to tumor size and nodal status

(2019) Anna Glajcar et al.   VIRCHOWS ARCHIV

Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma

(2019) Candice C. Poon et al.   Oncotarget

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

(2019) Cyril Neftel et al.   CELL

Identification of 3 subpopulations of tumor-infiltrating immune cells for malignant transformation of low-grade glioma

(2019) Jiacheng Lu et al.   Cancer Cell International

Predominance of M2 macrophages in gliomas leads to the suppression of local and systemic immunity

(2019) Aurobind Vidyarthi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A STAT3-based gene signature stratifies glioma patients for targeted therapy

(2019) Melanie Si Yan Tan et al.   Nature Communications

Identification of four immune subtypes characterized by distinct composition and functions of tumor microenvironment in intrahepatic cholangiocarcinoma

(2019) Sylvie Job et al.   HEPATOLOGY

T-cell Dysfunction in Glioblastoma: Applying a New Framework

(2018) Karolina I. Woroniecka et al.   CLINICAL CANCER RESEARCH

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

Prognostic significance of epidermal growth factor receptor expression in glioma patients

(2018) Junhong Li et al.   OncoTargets and Therapy

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015

(2018) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Single sample scoring of molecular phenotypes

(2018) Momeneh Foroutan et al.   BMC BIOINFORMATICS

Development and validation of an immune gene-set based Prognostic signature in ovarian cancer

(2018) Sipeng Shen et al.   EBioMedicine

Immune Gene Signature Delineates a Subclass of Papillary Thyroid Cancer with Unfavorable Clinical Outcomes

(2018) Kyuryung Kim et al.   Cancers

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

(2017) Michael Weller et al.   LANCET ONCOLOGY

Tumour-associated microglia/macrophages predict poor prognosis in high-grade gliomas and correlate with an aggressive tumour subtype

(2017) M. D. Sørensen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

(2017) Andrew S. Venteicher et al.   SCIENCE

Comprehensive RNA-seq transcriptomic profiling in the malignant progression of gliomas

(2017) Zheng Zhao et al.   Scientific Data

Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer

(2017) Thomas Karn et al.   JAMA Oncology

Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy

(2017) Sacha Gnjatic et al.   Journal for ImmunoTherapy of Cancer

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Immunotherapy and tumor microenvironment

(2016) Haidong Tang et al.   CANCER LETTERS

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies

(2016) Robert L. Bowman et al.   Cell Reports

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition

(2015) M. P. Mak et al.   CLINICAL CANCER RESEARCH

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Microenvironmental regulation of therapeutic response in cancer

(2015) Florian Klemm et al.   TRENDS IN CELL BIOLOGY

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Most Human Non-GCIMP Glioblastoma Subtypes Evolve from a Common Proneural-like Precursor Glioma

(2014) Tatsuya Ozawa et al.   CANCER CELL

Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin

(2014) Katherine A. Hoadley et al.   CELL

Immunotherapy for Primary Brain Tumors: No Longer a Matter of Privilege

(2014) P. E. Fecci et al.   CLINICAL CANCER RESEARCH

RNA-seq of 272 gliomas revealed a novel, recurrentPTPRZ1-METfusion transcript in secondary glioblastomas

(2014) Zhao-Shi Bao et al.   GENOME RESEARCH

Localizing seizure-susceptible brain regions associated with low-grade gliomas using voxel-based lesion-symptom mapping

(2014) Yinyan Wang et al.   NEURO-ONCOLOGY

Immune Heterogeneity of Glioblastoma Subtypes: Extrapolation from the Cancer Genome Atlas

(2013) T. Doucette et al.   Cancer Immunology Research

Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

(2013) Christel Devaud et al.   OncoImmunology

Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma

(2012) D. H. Gutmann et al.   GENOME RESEARCH

A signature of immune function genes associated with recurrence-free survival in breast cancer patients

(2011) Maria Libera Ascierto et al.   BREAST CANCER RESEARCH AND TREATMENT

Interaction of tumor cells with the microenvironment

(2011) Hendrik Ungefroren et al.   Cell Communication and Signaling

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Neurofibromatosis-1 Heterozygosity Increases Microglia in a Spatially and Temporally Restricted Pattern Relevant to Mouse Optic Glioma Formation and Growth

(2010) Grant W. Simmons et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE